Research Output 1988 2020

2020

Adaptive laboratory evolution of ale and lager yeast for improved brewing efficiency and beer quality

Gibson, B., Dahabieh, M., Krogerus, K., Jouhten, P., Magalhaes, F., Pereira, R., Siewers, V. & Vidgren, V., 17 Jan 2020, (Accepted/In press) In : Annual review of food science and technology. 11

Research output: Contribution to journalArticleScientificpeer-review

brewers yeast
brewing
beers
brewing industry
Yeasts
single cell protein
grass silage
enzymatic hydrolysis
dietary fiber
ammonia
2019

A deletion in the STA1 promoter determines maltotriose and starch utilization in STA1+ Saccharomyces cerevisiae strains

Krogerus, K., Magalhães, F., Kuivanen, J. & Gibson, B., 1 Sep 2019, In : Applied Microbiology and Biotechnology. 103, 18, p. 7597-7615 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Starch
Saccharomyces cerevisiae
Fermentation
Clustered Regularly Interspaced Short Palindromic Repeats
Glucan 1,4-alpha-Glucosidase

Bacterial protein for food and feed generated via renewable energy and direct air capture of CO2: Can it reduce land and water use?

Sillman, J., Nygren, L., Kahiluoto, H., Ruuskanen, V., Tamminen, A., Bajamundi, C., Nappa, M., Wuokko, M., Lindh, T., Vainikka, P., Pitkänen, J. P. & Ahola, J., 2019, In : Global Food Security. 22, p. 25-32 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Renewable Energy
bacterial proteins
Bacterial Proteins
renewable energy sources
renewable energy
3 Citations (Scopus)

Bioprospecting for brewers: Exploiting natural diversity for naturally diverse beers

Cubillos, F. A., Gibson, B., Grijalva-Vallejos, N., Krogerus, K. & Nikulin, J., 1 Jun 2019, In : Yeast. 36, 6, p. 383-398 16 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Beer
Yeast
Yeasts
Brewing
Saccharomyces

Cloning of novel bacterial xylanases from lignocellulose-enriched compost metagenomic libraries

Ellilä, S., Bromann, P., Nyyssönen, M., Itävaara, M., Koivula, A., Paulin, L. & Kruus, K., 2019, In : AMB Express. 9, 1, 124.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Metagenomics
Organism Cloning
Soil
Hydrolysis
Enzymes

Dynamic assembly of class II hydrophobins from T. reesei at the air-water interface

Hähl, H., Griffo, A., Safaridehkohneh, N., Heppe, J., Backes, S., Lienemann, M., Linder, M. B., Santen, L., Laaksonen, P. & Jacobs, K., 20 Jun 2019, In : Langmuir. 35, 28, p. 9202 - 9212 11 p.

Research output: Contribution to journalArticleScientificpeer-review

assembly
Proteins
Kinetics
Water
Monolayers
1 Citation (Scopus)

Electrode material studies and cell voltage characteristics of the in situ water electrolysis performed in a pH-neutral electrolyte in bioelectrochemical systems

Givirovskiy, G., Ruuskanen, V., Ojala, L. S., Lienemann, M., Kokkonen, P. & Ahola, J., 14 May 2019, In : Heliyon. 5, 5, e01690.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Electrolysis
Electrolytes
Electrodes
Water
Electric potential

Elucidating flavour formation and stress tolerance in brewing yeast hybrids

Krogerus, K., 2019, Aalto University. 133 p.

Research output: ThesisDissertationCollection of Articles

Open Access
brewing
stress tolerance
flavor
yeasts
brewers yeast
47 Downloads (Pure)

Fermentointiprosessin optimointi voihapon tuottamiseksi elintarviketeollisuuden sivuvirroista

Turunen, R., Sep 2019, 45 p.

Research output: ThesisBachelor's thesisTheses

Open Access
File
1 Citation (Scopus)

In situ water electrolyzer stack for an electrobioreactor

Givirovskiy, G., Ruuskanen, V., Ojala, L. S., Kokkonen, P. & Ahola, J., 2019, In : Energies. 12, 10, 1904.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Electrolysis
Hydrogen
Water
Hydrogen production
Energy efficiency

Multimodal Microorganism Development: Integrating Top-Down Biological Engineering with Bottom-Up Rational Design

Dahabieh, M. S., Thevelein, J. M. & Gibson, B., 22 Oct 2019, In : Trends in Biotechnology. 38, 3, p. 241-253 13 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Bioengineering
Microorganisms
Genes
Genome
Synthetic Biology
1 Citation (Scopus)

Novel genetic tools that enable highly pure protein production in Trichoderma reesei

Rantasalo, A., Vitikainen, M., Paasikallio, T., Jäntti, J., Landowski, C. P. & Mojzita, D., 22 Mar 2019, In : Scientific Reports. 9, 1, 12 p., 5032.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Trichoderma
Cellulase
Enzymes
Clustered Regularly Interspaced Short Palindromic Repeats
Glucose

Over 2000-fold increased production of the leaderless bacteriocin garvicin KS by increasing gene dose and optimization of culture conditions

Telke, A. A., Ovchinnikov, K. V., Vuoristo, K., Mathiesen, G., Torstensen, T. & Diep, D. B., 5 Mar 2019, In : Frontiers in Microbiology. 10, p. 389 9 p., 389.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Bacteriocins
Population Groups
Genes
Milk
Lactococcus

Physiology of aquatic microorganisms from the perspective of bioprocess development

Wang, Y., 2019, Aalto University.

Research output: ThesisDissertationCollection of Articles

Open Access
physiology
microorganisms
marine fungi
biotechnology
Euglena gracilis
2 Citations (Scopus)

Production, Characterization, and Application of an Alginate Lyase, AMOR-PL7A, from Hot Vents in the Arctic Mid-Ocean Ridge

Vuoristo, K. S., Fredriksen, L., Oftebro, M., Arntzen, M., Aarstad, O. A., Stokke, R., Steen, I. H., Hansen, L. D., Schüller, R. B., Aachmann, F. L., Horn, S. J. & Eijsink, V. G. H., 13 Mar 2019, In : Journal of Agricultural and Food Chemistry. 67, 10, p. 2936-2945 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Seaweed
Vents
Oceans and Seas
macroalgae
Arctic region
2018
1 Citation (Scopus)

Adhesion Properties of Freestanding Hydrophobin Bilayers

Hähl, H., Vargas, J. N., Jung, M., Griffo, A., Laaksonen, P., Lienemann, M., Jacobs, K., Seemann, R. & Fleury, J. B., 24 Jul 2018, In : Langmuir. 34, 29, p. 8542-8549 8 p.

Research output: Contribution to journalArticleScientificpeer-review

adhesion
Adhesion
proteins
Proteins
Monolayers
12 Citations (Scopus)

Alternative Saccharomyces interspecies hybrid combinations and their potential for low-temperature wort fermentation

Nikulin, J., Krogerus, K. & Gibson, B., 1 Jan 2018, In : Yeast. 35, 1, p. 113-127 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Saccharomyces
Beer
Yeast
Fermentation
Temperature
2 Citations (Scopus)

Assessment of the scalability of a microtiter plate system for screening of oleaginous microorganisms

Kosa, G., Vuoristo, K., Horn, S. J., Zimmermann, B., Afseth, N. K., Kohler, A. & Shapaval, V., 4 Nov 2018, In : Applied Microbiology and Biotechnology. 102, 11, p. 4915-4925 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Biomass
Bioreactors
Mortierella
Lipids
Mucor
6 Citations (Scopus)

A Unique Saccharomyces cerevisiae x Saccharomyces uvarum Hybrid Isolated From Norwegian Farmhouse Beer: Characterization and Reconstruction

Krogerus, K., Preiss, R. & Gibson, B., 24 Sep 2018, In : Frontiers in Microbiology. 9, SEP, 2253.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Saccharomyces
Saccharomyces cerevisiae
Genome
Biofuels
Wine

Bits and biomass: A roadmap to the digitalisation-empowered bioeconomy

Leinonen, A. (ed.), Åkerman, M. (ed.), Kruus, K. (ed.), Asikainen, A. (ed.), Muhonen, T. (ed.), Kohl, J. (ed.), Ala-Ilomäki, J., Arvas, M., Backman, J., Hantula, J., Häme, T., Isto, P., Kangas, A., Lantto, R., Nieminen, K., Nordlund, E., Pastell, M., Peltola, R., Pesonen, L., Pitkänen, J-P. & 7 others, Piri, T., Pusenius, J., Seisto, A., Suomi, P., Utriainen, M., Viiri, H. & Väätäinen, K., 2018, VTT Technical Research Centre of Finland. 51 p. (VTT Visions; No. 12).

Research output: Book/ReportReport

Open Access
Natural resources
Biomass
Raw materials
Production control
Transparency
7 Citations (Scopus)

Comparative Assessment of Enzymatic Hydrolysis for Valorization of Different Protein-Rich Industrial Byproducts

Lapeña, D., Vuoristo, K., Kosa, G., Horn, S. J. & Eijsink, V. G. H., 24 Aug 2018, In : Journal of Agricultural and Food Chemistry. 66, 37, p. 9738-9749 12 p.

Research output: Contribution to journalArticleScientificpeer-review

industrial byproducts
Enzymatic hydrolysis
enzymatic hydrolysis
byproducts
Byproducts
5 Citations (Scopus)
Open Access
Breweries
Diacetyl
Beer
Saccharomyces
Yeast
3 Citations (Scopus)

Differential evolution of Strecker and non-Strecker aldehydes during aging of pale and dark beers

Gibson, B., Aumala, V., Heiniö, R-L., Mikkelson, A. & Honkapää, K., 2018, In : Journal of Cereal Science. 83, p. 130-138 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Beer
beers
Aldehydes
aldehydes
Aging of materials
3 Citations (Scopus)

Enhanced triacylglycerol production with genetically modified Trichosporon oleaginosus

Koivuranta, K., Castillo, S., Jouhten, P., Ruohonen, L., Penttilä, M. & Wiebe, M. G., 21 Jun 2018, In : Frontiers in Microbiology. 9, JUN, 1337.

Research output: Contribution to journalArticleScientificpeer-review

Trichosporon
Pyruvic Acid
Triglycerides
Xylose
Oxidoreductases
9 Citations (Scopus)

Enhanced wort fermentation with de novo lager hybrids adapted to high-ethanol environments

Krogerus, K., Holmström, S. & Gibson, B., 1 Feb 2018, In : Applied and Environmental Microbiology. 84, 4, e02302-17.

Research output: Contribution to journalArticleScientificpeer-review

wort (brewing)
Fermentation
fermentation
ethanol
Ethanol
5 Citations (Scopus)

Euglena gracilis growth and cell composition under different temperature, light and trophic conditions

Wang, Y., Seppänen-Laakso, T., Rischer, H. & Wiebe, M. G., 1 Apr 2018, In : PLoS ONE. 13, 4, e0195329.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Euglena gracilis
Light
Biomass
Temperature
Cells
Open Access
interspecific hybridization
heterosis
ciders
yeasts
fermentation
18 Citations (Scopus)

Mediator-free enzymatic electrosynthesis of formate by the Methanococcus maripaludis heterodisulfide reductase supercomplex

Lienemann, M., Deutzmann, J. S., Milton, R. D., Sahin, M. & Spormann, A. M., 1 Apr 2018, In : Bioresource Technology. 254, p. 278-283 6 p.

Research output: Contribution to journalArticleScientificpeer-review

formic acid
Enzymes
enzyme
Assays
Enzyme electrodes
3 Citations (Scopus)

Microalgal CO2 capture at extreme pH values

Piiparinen, J., Barth, D., Eriksen, N. T., Teir, S., Spilling, K. & Wiebe, M. G., 1 Jun 2018, In : Algal Research. 32, p. 321-328 8 p.

Research output: Contribution to journalArticleScientificpeer-review

carbon dioxide
air
algae
Coccomyxa
uptake mechanisms
7 Citations (Scopus)

Microbial Protein Produced from Brown Seaweed and Spruce Wood as a Feed Ingredient

Sharma, S., Hansen, L. D., Hansen, J. O., Mydland, L. T., Horn, S. J., Øverland, M., Eijsink, V. G. H. & Vuoristo, K. S., 8 Aug 2018, In : Journal of Agricultural and Food Chemistry. 66, 31, p. 8328-8335 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Seaweed
Phaeophyceae
microbial proteins
Fermentation
Picea
1 Citation (Scopus)

Overexpressed maltose transporters in laboratory and lager yeasts: Localization and competition with endogenous transporters

Vidgren, V. & Londesborough, J., 1 Oct 2018, In : Yeast. 35, 10, p. 567-576 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Maltose
Beer
Cell membranes
Yeast
Yeasts

Soxhlet extraction of mucic acid from fungal biomass

Thomas, D. A., Virtanen, T. & Wiebe, M. G., 2018, In : Separation Science and Technology. 53, 6, p. 903-909 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Biomass
Acids
Lactones
Crystallization
Dilution
4 Citations (Scopus)

Towards patterned bioelectronics: facilitated immobilization of exoelectrogenic Escherichia coli with heterologous pili

Lienemann, M., TerAvest, M. A., Pitkänen, J. P., Stuns, I., Penttilä, M., Ajo-Franklin, C. M. & Jäntti, J., 1 Nov 2018, In : Microbial Biotechnology. 11, 6, p. 1184-1194 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Immobilization
Escherichia coli
Biofilms
Mannose
Shewanella
6 Citations (Scopus)

Traditional Norwegian Kveik Are a Genetically Distinct Group of Domesticated Saccharomyces cerevisiae Brewing Yeasts

Preiss, R., Tyrawa, C., Krogerus, K., Garshol, L. M. & Van Der Merwe, G., 12 Sep 2018, In : Frontiers in Microbiology. 9, SEP, 2137.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Saccharomyces cerevisiae
Yeasts
Fermentation
Flocculation
Food and Beverages
1 Citation (Scopus)

Trans-regulation and localization of orthologous maltose transporters in the interspecies lager yeast hybrid

Vidgren, V. & Gibson, B., 1 Sep 2018, In : FEMS Yeast Research. 18, 6, 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Maltose
Saccharomyces cerevisiae
Yeasts
Cell Membrane
Saccharomyces
2017
12 Citations (Scopus)

A design-build-test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic models

Miskovic, L., Alff-Tuomala, S., Soh, K. C., Barth, D., Salusjärvi, L., Pitkänen, J-P., Ruohonen, L., Penttilä, M. & Hatzimanikatis, V., 2017, In : Biotechnology for Biofuels. 10, 1, 166.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Xylose
Glycolysis
Saccharomyces cerevisiae
kinetics
Kinetics

Bittejä ja biomassaa: Tiekartta digitalisaation vauhdittamaan biotalouteen

Leinonen, A. (ed.), Åkerman, M. (ed.), Kruus, K. (ed.), Asikainen, A. (ed.), Muhonen, T. (ed.), Kohl, J. (ed.), Ala-Ilomäki, J., Arvas, M., Backman, J., Hantula, J., Holmala, K., Häme, T., Kangas, A., Isto, P., Lantto, R., Nieminen, K., Pastell, M., Nordlund, E., Peltola, R., Pesonen, L. & 8 others, Pitkänen, J-P., Piri, T., Pusenius, J., Seisto, A., Suomi, P., Utriainen, M., Viiri, H. & Väätäinen, K., 2017, VTT Technical Research Centre of Finland. 103 p. (VTT Visions; No. 11).

Research output: Book/ReportReport

Open Access
36 Citations (Scopus)

Development of a low-cost cellulase production process using Trichoderma reesei for Brazilian biorefineries

Ellilä, S., Fonseca, L., Uchima, C., Cota, J., Goldman, G. H., Saloheimo, M., Sacon, V. & Siika-Aho, M., 2017, In : Biotechnology for Biofuels. 10, 1, p. 30

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Trichoderma
Cellulase
production cost
Saccharum
Costs and Cost Analysis
6 Citations (Scopus)

Enhancing fungal production of galactaric acid

Barth, D. & Wiebe, M. G., 1 May 2017, In : Applied Microbiology and Biotechnology. 101, 10, p. 4033-4040 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Ammonium Compounds
Solubility
Ions
Nitric Acid
Trichoderma
11 Citations (Scopus)

Evolutionary engineering in chemostat cultures for improved maltotriose fermentation kinetics in saccharomyces pastorianus lager brewing yeast

Brickwedde, A., van den Broek, M., Geertman, J-MA., Magalhães, F., Kuijpers, N. G. A., Gibson, B., Pronk, J. T. & Daran, J-MG., 8 Sep 2017, In : Frontiers in Microbiology. 8, SEP, p. 1690 1690.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Saccharomyces
Fermentation
Yeasts
Ethanol
Hypergravity
3 Citations (Scopus)

Exploring the potential of Saccharomyces eubayanus as a parent for new interspecies hybrid strains in winemaking

Magalhães, F., Krogerus, K., Castillo, S., Ortiz-Julien, A., Dequin, S. & Gibson, B., 1 Aug 2017, In : FEMS Yeast Research. 17, 5, fox049.

Research output: Contribution to journalArticleScientificpeer-review

Saccharomyces
Wine
Fermentation
Vitis
Saccharomyces cerevisiae

Immobilized yeast cells and secondary metabolites

Djordjevic, V., Willaert, R., Gibson, B. & Nedovic, V., 2017, Fungal Metabolites. Mérillon, JM. & Ramawat, K. (eds.). Springer, p. 599-638 40 p. (Reference Series in Phytochemistry).

Research output: Chapter in Book/Report/Conference proceedingChapter or book articleProfessional

Metabolites
Yeast
Cells
Flavors
Bioreactors
16 Citations (Scopus)
Open Access
Saccharomyces
Yeast
Fermentation
Saccharomyces cerevisiae
Temperature
18 Citations (Scopus)
Open Access
Brewing
Saccharomyces
Beer
Yeast
Flavors
9 Citations (Scopus)

Molecular structure of hydrophobins studied with site-directed mutagenesis and vibrational sum-frequency generation spectroscopy

Meister, K., Paananen, A., Speet, B., Lienemann, M. & Bakker, H., 12 Oct 2017, In : The Journal of Physical Chemistry B. 121, 40, p. 9398-9402 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
mutagenesis
Mutagenesis
Vibrational spectra
Molecular structure
molecular structure
27 Citations (Scopus)

New yeasts-new brews: Modern approaches to brewing yeast design and development

Gibson, B., Geertman, J-MA., Hittinger, C. T., Krogerus, K., Libkind, D., Louis, E. J., Magalhães, F. & Sampaio, J. P., 2017, In : FEMS Yeast Research. 17, 4, 13 p., fox038.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Yeasts
Saccharomyces
Industry
Genomic Instability
Research
38 Citations (Scopus)

Novel brewing yeast hybrids: Creation and application

Krogerus, K., Magalhães, F., Vidgren, V. & Gibson, B., Jan 2017, In : Applied Microbiology and Biotechnology. 101, 1, p. 65-78 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Yeasts
Saccharomyces cerevisiae
Saccharomyces
Genomic Instability
Wine
5 Citations (Scopus)

Scaling up and scaling down the production of galactaric acid from pectin using Trichoderma reesei

Paasikallio, T., Huuskonen, A. & Wiebe, M., 11 Jul 2017, In : Microbial Cell Factories. 16, 1, 119.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Trichoderma
Acids
Bioconversion
uronate dehydrogenase
pectin