Projects per year
Personal profile
Short bio
The pursuit of cutting-edge biotechnological solutions is at the forefront of my professional journey. With a strong foundation in biochemistry and a keen eye for innovation, my role involves building collaborative consortia and strategizing IP development, particularly in the realm of fungal platforms and protein applications.
Earlier work as has honed my expertise in protein sciences, a critical skill that complements my responsibilities at VTT. Spearheading grant applications and commercialization strategies, our team's efforts are geared towards propelling the frontiers of food, biomaterials, enzymes, and pharmaceuticals, while also fostering essential industry partnerships.
Keywords in my research are: Protein Science, Bioprocess Engineering, Raman Spectroscopy, Pharmaceutical Proteins, Enzymes, Protein Engineering, Cell Free Protein Synthesis (CFPS), and Biotechnology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Manufacturing and processing, Doctorate, Towards new enzymes: protein engineering versus bioinformatic studies, University of Oulu
Mar 2008 → 20 Mar 2010
Award Date: 20 Mar 2010
Life sciences, Master, Characterization of the hinge TIM-mutants P168A and A178L, University of Oulu
Jan 2003 → Feb 2008
Award Date: 10 Feb 2008
Life sciences, Bachelor, Sources, applications, and gel properties of basic proteins, Utrecht University of Applied Sciences
Dec 1990 → Jun 1997
Award Date: 31 May 1997
External positions
University Researcher, University of Helsinki
3 Jan 2011 → 30 Sept 2018
Parental Leave
1 Apr 2010 → 31 Dec 2010
PhD student/Researcher, University of Oulu
3 Jan 2003 → 31 Mar 2010
Test Supervisor/Chemical Administrator, National Institute for Public Health and the Environment (RIVM)
1 Dec 1999 → 31 Dec 2002
Skills and expertise
- Biotechnology
- Raman Spectroscopy
- Enzyme characterization
- enzyme applications
- Enzyme discovery
- Protein chemistry
- Protein engineering
- Protein production
- Protein purification
- Pharmaceutical Proteins
- cell free
- cell/ primary cell culture
- Cellular agriculture
- bioprocess engineering
- Management and Organization
- project coordination
- project management
- project proposal preparation
- teaching
- bacteria
- fungi
- western blot
- laboratory maintenance
Fingerprint
Dive into the research topics where Marco Casteleijn is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
BIOCOLL: Producing Collagen peptides in Trichoderma Reesei using precision fermentation technology
Pietiäinen, M. (Manager), Healy-Rehn, M. (PI), Nakari-Setälä, T. (Owner), Aalto, A. (Participant), Bhattacharjee, A. (Participant), Casteleijn, M. (Participant) & Tal, R. (Participant)
1/09/25 → 28/02/27
Project: Business Finland project
-
Fungi2Pharma: Accelerating Protein Production with Natures Resilience
Casteleijn, M. (Manager)
1/06/25 → 30/11/25
Project: Business Finland project
-
CERAFIM: Cellular Agriculture for Sustainable Food and Materials
Barth, D. (Manager), Toivari, M. (Participant), Paananen, A. (Participant), Lille, M. (Participant), Koivuranta, K. (Participant), Valtonen, A. (Participant), Salusjärvi, L. (Participant), Casteleijn, M. (Participant), Aalto, A. (Participant), Behm, K. (Participant), Sarvola, I.-M. (Participant), Suomalainen, M. (Participant), Hentula, M. (Participant), Småros, F. (Participant), Troullier, M. (Participant), Dilokpimol, A. (Participant), Abendroth, U. (Participant), Tsitko, I. (Participant), Luecha, J. (Participant), Juvonen, R. (Participant), Nordlund, E. (Participant) & Sözer, N. (Participant)
1/05/22 → 30/06/24
Project: Business Finland project
-
Precision Fermentation: From Biotechnology to Sustainable Nutrition (21063)
Casteleijn, M. (Manager) & Sözer, N. (Participant)
1/06/21 → 31/12/21
Project: EU project
-
Beyond In Vivo, Pharmaceutical Molecule Production in Cell-Free Systems and the Use of Noncanonical Amino Acids Therein
Casteleijn, M. G., Abendroth, U., Zemella, A., Walter, R., Rashmi, R., Haag, R. & Kubick, S., 22 Feb 2025, In: Chemical Reviews. 125, 3, p. 1303-1331 29 p.Research output: Contribution to journal › Review Article › peer-review
Open Access5 Citations (Scopus) -
Label-free analytical characterization of brazzein produced with the filamentous fungus Trichoderma reesei
Mojzita, D., Aro, N., Kontturi, J., Kögler, M., Nordlund, E., Hosia, W. & Casteleijn, M. G., 2025, In: Frontiers in Bioengineering and Biotechnology. 13, 14 p., 1688495.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Downloads (Pure) -
Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy
Itkonen, J., Ghemtio, L., Pellegrino, D., Jokela, P. J., Xhaard, H. & Casteleijn, M. G., Aug 2022, In: Pharmaceutics. 14, 8, 18 p., 1639.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access9 Citations (Scopus) -
Assessment of recombinant protein production in E. coli with Time-Gated Surface Enhanced Raman Spectroscopy (TG-SERS)
Kögler, M., Itkonen, J., Viitala, T. & Casteleijn, M. G., 12 Feb 2020, In: Scientific Reports. 10, 1, p. 2472 11 p., 2472.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access25 Citations (Scopus) -
Characterization, stability, and in vivo efficacy studies of recombinant human CNTF and its permeation into the neural retina in ex vivo organotypic retinal explant culture models
Itkonen, J., Annala, A., Tavakoli, S., Arango-Gonzalez, B., Ueffing, M., Toropainen, E., Ruponen, M., Casteleijn, M. G. & Urtti, A., 30 Jun 2020, In: Pharmaceutics. 12, 7, p. 1-31 31 p., 611.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile11 Citations (Scopus)159 Downloads (Pure)
-
Molecular Biotechnology (Journal)
Casteleijn, M. (Reviewer)
2018Activity: Publication peer-review and editorial work types › Publication Peer-review
-
European Journal of Pharmaceutical Sciences (Journal)
Casteleijn, M. (Reviewer)
2018Activity: Publication peer-review and editorial work types › Publication Peer-review
-
Evaluator of MSCA research proposals
Casteleijn, M. (Examiner)
2016 → 2018Activity: Evaluation, assessment or examination types › Dissertation examiner or opponent