Mark van Gils

  • Phone+358405583184
1992 …2020

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A Decision Support System for Diagnostics and Treatment Planning in Traumatic Brain Injury

Umer, A., Mattila, J., Liedes, H., Koikkalainen, J., Lotjonen, J., Katila, A., Frantzen, J., Newcombe, V., Tenovuo, O., Menon, D. & van Gils, M., 1 May 2019, In : IEEE Journal of Biomedical and Health Informatics. 23, 3, p. 1261-1268 8370619.

Research output: Contribution to journalArticleScientificpeer-review

2 Citations (Scopus)

A disease state fingerprint for evaluation of Alzheimer's disease

Mattila, J., Koikkalainen, J., Virkki, A., Simonsen, A., van Gils, M., Waldemar, G., Soininen, H., Lötjönen, J. & The Alzheimer’s Disease Neuroimaging Initiative, 2011, In : Journal of Alzheimer's Disease. 27, 1, p. 163-176 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
67 Citations (Scopus)

Admission Levels of Total Tau and β-Amyloid Isoforms 1–40 and 1–42 in Predicting the Outcome of Mild Traumatic Brain Injury

Hossain, I., Mohammadian, M., Takala, R. S. K., Tenovuo, O., Azurmendi Gil, L., Frantzén, J., van Gils, M., Hutchinson, P. J., Katila, A. J., Maanpää, H. R., Menon, D. K., Newcombe, V. F., Tallus, J., Hrusovsky, K., Wilson, D. H., Gill, J., Blennow, K., Sanchez, J. C., Zetterberg, H. & Posti, J. P., 13 May 2020, In : Frontiers in Neurology. 11, 325.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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7 Downloads (Pure)

Application of the PredictAD Decision Support Tool to a Danish Cohort of Patients with Alzheimer's Disease and Other Dementias

Simonsen, A., Mattila, J., Hejl, A-M., Garde, E., van Gils, M., Thomsen, C., Lötjönen, J., Soininen, H. & Waldemar, G., 2014, In : Dementia and Geriatric Cognitive Disorders. 37, 3-4, p. 207-213

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)

Application of the predictad software tool to predict progression in patients with mild cognitive impairment

Simonsen, A. H., Mattila, J., Hejl, A. M., Frederiksen, K. S., Herukka, S. K., Hallikainen, M., van Gils, M., Lötjönen, J., Soininen, H. & Waldemar, G., 2012, In : Dementia and Geriatric Cognitive Disorders. 34, 5-6, p. 344-350

Research output: Contribution to journalArticleScientificpeer-review

Open Access
11 Citations (Scopus)

Assessment of surgical stress during general anaesthesia

Huiku, M., Kymäläinen, M., Takala, P., Uutela, K., Viertiö-Oja, H., Rantanen, M., van Gils, M., Korhonen, I. & Yli-Hankala, A., 2007, In : British Journal of Anaesthesia. 98, 4, p. 447-455

Research output: Contribution to journalArticleScientificpeer-review

161 Citations (Scopus)

Automatically computed rating scales from MRI for patients with cognitive disorders

Koikkalainen, J. R., Rhodius-Meester, H. F. M., Frederiksen, K. S., Bruun, M., Hasselbalch, S. G., Baroni, M., Mecocci, P., Vanninen, R., Remes, A., Soininen, H., van Gils, M., van der Flier, W. M., Scheltens, P., Barkhof, F., Erkinjuntti, T. & Lötjönen, J. M. P., 1 Sep 2019, In : European Radiology. 29, 9, p. 4937-4947

Research output: Contribution to journalArticleScientificpeer-review

4 Citations (Scopus)

Automatic MRI Quantifying Methods in Behavioral-Variant Frontotemporal Dementia Diagnosis

Cajanus, A., Hall, A., Koikkalainen, J., Solje, E., Tolonen, A., Urhemaa, T., Liu, Y., Haanpää, R. M., Hartikainen, P., Helisalmi, S., Korhonen, V., Rueckert, D., Hasselbalch, S., Waldemar, G., Mecocci, P., Vanninen, R., van Gils, M., Soininen, H., Lötjönen, J. & Remes, A. M., 3 Apr 2018, In : Dementia and Geriatric Cognitive Disorders Extra. 8, 1, p. 51-59

Research output: Contribution to journalArticleScientificpeer-review

Open Access
5 Citations (Scopus)

Biosignal processing methods to guide cardiac patients to perform safe and beneficial exercise for rehabilitation

Runtti, H., Honka, A., Chouvarda, I., Michail, E., Kokonozi, A., Merilahti, J., Pärkkä, J. & van Gils, M., 2013, In : International Journal of Bioelectromagnetism. 15, 1, p. 20-25 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Building the IMPROVE data library

Korhonen, I., Ojaniemi, J., Nieminen, K., van Gils, M., Heikelä, A. & Kari, A., 1997, In : IEEE Engineering in Medicine and Biology Magazine. 16, 6, p. 25-32

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)

Collecting EEG signals in the IMPROVE data library

Thomsen, C., Grade, J., Nieminen, K., Langford, R., Ghosh, R., Jensen, K., van Gils, M., Rosenfalck, A., Prior, P. & White, S., 1997, In : IEEE Engineering in Medicine and Biology Magazine. 16, 6, p. 33-40

Research output: Contribution to journalArticleScientificpeer-review

17 Citations (Scopus)

Comparison of train-of-four ratios measured with Datex-Ohmeda's M-NMT MechanoSensor and M-NMT ElectroSensor

Salminen, J., van Gils, M., Paloheimo, M. & Yli-Hankala, A., 2016, In : Journal of Clinical Monitoring and Computing. 30, 3, p. 295-300

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)

Consistensy of Muistikko web-based cognitive test while performed at clinic and at home

Lötjönen, J., Paajanen, T., Bruun, M., Mahdiani, S., Baroni, M., Rhodius-Meester, H., Herukka, S-K., Lemstra, A. W., Pikkarainen, M., Hänninen, T., van Gils, M., Hasselbalch, S., Mecocci, P., Remes, A. M., van der Flier, W. M. & Soininen, H., 1 Jul 2018, In : Alzheimer's and Dementia. 14, 7, p. 418-418 P1-328.

Research output: Contribution to journalArticleScientificpeer-review

Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury

Posti, J. P., Takala, R. S. K., Lagerstedt, L., Dickens, A. M., Hossain, I., Mohammadian, M., Ala-Seppälä, H., Frantzén, J., van Gils, M., Hutchinson, P. J., Katila, A. J., Maanpaä, H. R., Menon, D. K., Newcombe, V. F., Tallus, J., Hrusovsky, K., Wilson, D. H., Gill, J., Sanchez, J. C., Tenovuo, O. & 2 others, Zetterberg, H. & Blennow, K., 15 Jul 2019, In : Journal of Neurotrauma. 36, 14, p. 2178-2189

Research output: Contribution to journalArticleScientificpeer-review

13 Citations (Scopus)

Design and application of a generic clinical decision support system for multiscale data

Mattila, J., Koikkalainen, J., Virkki, A., van Gils, M. & Lötjönen, J., 2012, In : IEEE Transactions on Biomedical Engineering. 59, 1, p. 234-240

Research output: Contribution to journalArticleScientificpeer-review

33 Citations (Scopus)

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline

Pekkala, T., Hall, A., Ngandu, T., Gils, M. V., Helisalmi, S., Hänninen, T., Kemppainen, N., Liu, Y., Lötjönen, J., Paajanen, T., Rinne, J. O., Soininen, H., Kivipelto, M. & Solomon, A., Jul 2020, In : Frontiers in Aging Neuroscience. 12, 228.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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4 Downloads (Pure)

Detecting frontotemporal dementia syndromes using MRI biomarkers

Bruun, M., Koikkalainen, J., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., van Gils, M., Soininen, H., Remes, A., Hartikainen, P., Waldemar, G., Mecocci, P., Barkhof, F., Pijnenburg, Y., van der Flier, W. M., Hasselbalch, S. G., Lötjönen, J. & Frederiksen, K. S., 4 Feb 2019, In : NeuroImage: Clinical. 22, p. 101711 101711.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
8 Citations (Scopus)

Detecting frontotemporal dementia using a novel MRI imaging biomarker: The anterior versus posterior index

Bruun, M., Koikkalainen, J., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., van Gils, M., Soininen, H., Remes, A. M., Waldemar, G., Mecocci, P., van der Flier, W. M., Hasselbalch, S., Jyrki, L. & Frederiksen, K. S., 1 Jul 2018, In : Alzheimer's and Dementia. 14, 7, p. 821-822 P2-350.

Research output: Contribution to journalArticleScientific

Developing personalised solutions for the treatment of traumatic brain injury: The TBIcare project

van Gils, M. & Tenovuo, O., 2011, In : CyberTherapy and Rehabilitation Magazine. 2011, 1, p. 34-35

Research output: Contribution to journalArticleProfessional

Open Access

Different combinations of diagnostic tests discriminate specific subtypes of dementia

Rhodius-Meester, H. F. M., Bruun, M., Baroni, M., Gjerum, L., Remes, A. M., Urhemaa, T., Tolonen, A., Rueckert, D., van Gils, M., Lemstra, E., Barkhof, F., Frederiksen, K. S., Waldemar, G., Scheltens, P., Soininen, H., Mecocci, P., Koikkalainen, J., Lötjönen, J. & van der Flier, W. M., 1 Jul 2018, In : Alzheimer's and Dementia. 10, 7, p. 820-821 P2-349.

Research output: Contribution to journalArticleScientific

Disease-related determinants are associated with mortality in dementia due to Alzheimer's disease

Rhodius-Meester, H. F. M., Liedes, H., Koene, T., Lemstra, A. W., Teunissen, C. E., Barkhof, F., Scheltens, P., van Gils, M., Lötjönen, J. & van der Flier, W. M., 2018, In : Alzheimer's Research and Therapy. 10, 1, 23.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
7 Citations (Scopus)

Early Levels of Glial Fibrillary Acidic Protein and Neurofilament Light Protein in Predicting the Outcome of Mild Traumatic Brain Injury

Hossain, I., Mohammadian, M., Takala, R. S. K., Tenovuo, O., Lagerstedt, L., Ala-Seppälä, H. M., Frantzén, J., van Gils, M., Hutchinson, P. J., Katila, A. J., Maanpää, H-R., Menon, D., Newcombe, V., Tallus, J., Hrusovsky, K., Wilson, D., Blennow, K., Sanchez, J-C., Zetterberg, H. & Posti, J. P., 15 May 2019, In : Journal of Neurotrauma. 36, 10, p. 1551-1560

Research output: Contribution to journalArticleScientificpeer-review

7 Citations (Scopus)

EEG spectral entropy, heart rate, photoplethysmography and motor responses to skin incision during sevoflurane anaesthesia

Seitsonen, E., Korhonen, I., van Gils, M., Huiku, M., Lötjönen, J., Korttila, K. & Yli-Hankala, A., 2005, In : Acta Anaesthesiologica Scandinavica. 49, 3, p. 284-292

Research output: Contribution to journalArticleScientificpeer-review

70 Citations (Scopus)

Entropy is more resistant to artifacts than bispectral index in brain-dead organ donors

Wennervirta, J., Salmi, T., Hynynen, M., Yli-Hankala, A., Koivusalo, A-M., van Gils, M., Pöyhiä, R. & Vakkuri, A., 2007, In : Intensive Care Medicine. 33, 1, p. 133-136

Research output: Contribution to journalArticleScientificpeer-review

25 Citations (Scopus)

Evaluating combinations of diagnostic tests to discriminate different dementia types

Bruun, M., Rhodius-Meester, H. F. M., Koikkalainen, J., Baroni, M., Gjerum, L., Lemstra, A. W., Barkhof, F., Remes, A. M., Urhemaa, T., Tolonen, A., Rueckert, D., van Gils, M., Frederiksen, K. S., Waldemar, G., Scheltens, P., Mecocci, P., Soininen, H., Lötjönen, J., Hasselbalch, S. G. & van der Flier, W. M., 1 Jan 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 509-518 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
9 Citations (Scopus)

Exploring the impact of sleep and stress on daily physical activity of cardiac patients: A preliminary study

Livitckaia, K., Kouidi, E., Mavromoustakos, B. P., Maglaveras, N., van Gils, M. & Chouvarda, I., 2019, In : Hippokratia. 23, 1, p. 15-20 6 p.

Research output: Contribution to journalArticleScientific

Open Access

Framework for biosignal interpretation in intensive care and anesthesia

Saranummi, N., Korhonen, I., Van Gils, M. & Kari, A., 1 Dec 1997, In : Methods of Information in Medicine. 36, 4-5, p. 340-344

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)

Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort

Muurling, M., Rhodius-Meester, H. F. M., Pärkkä, J., van Gils, M., Frederiksen, K. S., Bruun, M., Hasselbalch, S. G., Soininen, H., Herukka, S. K., Hallikainen, M., Teunissen, C. E., Visser, P. J., Scheltens, P., van der Flier, W. M., Mattila, J., Lötjönen, J. & de Boer, C., 2020, In : Journal of Alzheimer's disease : JAD. 76, 3, p. 1061-1070 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 are not specific biomarkers for mild CT-negative traumatic brain injury

Posti, J. P., Hossain, I., Takala, R. S. K., Liedes, H., Newcombe, V., Outtrim, J., Katila, A. J., Frantzén, J., Ala-Seppälä, H., Coles, J. P., Kyllönen, A., Maanpää, H-R., Tallus, J., Hutchinson, P. J., van Gils, M., Menon, D. K., Tenovuo, O. & TBI Care Investigators, 1 Apr 2017, In : Journal of Neurotrauma. 34, 7, p. 1427-1438 12 p.

Research output: Contribution to journalArticleScientificpeer-review

32 Citations (Scopus)

Glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 as outcome predictors in traumatic brain injury

Takala, R. S. K., Posti, J. P., Runtti, H., Newcombe, V. F., Outtrim, J., Katila, A. J., Frantzén, J., Ala-Seppälä, H., Kyllönen, A., Maanpää, H-R., Tallus, J., Hossain, M. I., Coles, J. P., Hutchinson, P., van Gils, M., Menon, D. K. & Tenovuo, O., 2016, In : World Neurosurgery. 87, p. 8-20

Research output: Contribution to journalArticleScientificpeer-review

41 Citations (Scopus)

Graphical Tasks to Measure Upper Limb Function in Patients with Parkinson's Disease: Validity and Response to Dopaminergic Medication

Smits, E. J., Tolonen, A. J., Cluitmans, L., van Gils, M., Zietsma, R. C., Borgemeester, R. W. K., van Laar, T. & Maurits, N. M., 1 Jan 2017, In : IEEE Journal of Biomedical and Health Informatics. 21, 1, p. 283-289

Research output: Contribution to journalArticleScientificpeer-review

10 Citations (Scopus)

Health monitoring in the home of the future

Korhonen, I., Pärkkä, J. & van Gils, M., 2003, In : IEEE Engineering in Medicine and Biology Magazine. 22, 3, p. 66-73

Research output: Contribution to journalArticleScientificpeer-review

344 Citations (Scopus)

Heart rate variability responses to skin incision in 0.8 MAC sevoflurane anaesthesia

Korhonen, I., Seitsonen, E., van Gils, M., Korttila, K. & Yli-Hankala, A., 2003, In : International Journal of Bioelectromagnetism. 5, 1, p. 240-241

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Identification of adequate neurally adjusted ventilatory assist (NAVA) during systematic increases in the NAVA level

Ververidis, D., van Gils, M., Passath, C., Takala, J. & Brander, L., 2011, In : IEEE Transactions on Biomedical Engineering. 58, 9, p. 2598-2606

Research output: Contribution to journalArticleScientificpeer-review

Open Access
13 Citations (Scopus)

Identification of peak V in brainstem auditory evoked potentials with neural networks

Habraken, J. B. A., van Gils, M. J. & Cluitmans, P. J. M., 1 Jan 1993, In : Computers in Biology and Medicine. 23, 5, p. 369-380

Research output: Contribution to journalArticleScientificpeer-review

15 Citations (Scopus)

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study

Bruun, M., Frederiksen, K. S., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., Koikkalainen, J., Urhemaa, T., Tolonen, A., van Gils, M., Tong, T., Guerrero, R., Rueckert, D., Dyremose, N., Bo Andersen, B., Simonsen, A. H., Lemstra, A. W., Hallikainen, M., Kurl, S., Herukka, S-K., Remes, A. M. & 6 others, Waldemar, G., Soininen, H., Mecocci, P., van der Flier, W. M., Lötjönen, J. & Hasselbalch, S. G., Feb 2019, In : Current Alzheimer Research. 16, 2, p. 91-101

Research output: Contribution to journalArticleScientificpeer-review

7 Citations (Scopus)

Impact of a clinical decision support tool on prediction of progression in early-stage dementia: A prospective validation study

Bruun, M., Frederiksen, K. S., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., Koikkalainen, J., Urhemaa, T., Tolonen, A., van Gils, M., Rueckert, D., Dyremose, N., Andersen, B. B., Lemstra, A. W., Hallikainen, M., Kurl, S., Herukka, S. K., Remes, A. M., Waldemar, G., Soininen, H., Mecocci, P. & 3 others, Van Der Flier, W. M., Lötjönen, J. & Hasselbalch, S. G., 20 Mar 2019, In : Alzheimer's Research and Therapy. 11, 1, 25.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
3 Citations (Scopus)

Improved classification of Alzheimer's disease data via removal of nuisance variability

Koikkalainen, J., Pölönen, H., Mattila, J., van Gils, M., Soininen, H. & Lötjönen, J., 2012, In : PLoS ONE. 7, 2, 12 p., e31112.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
34 Citations (Scopus)

Increased variation of the response index of nociception during noxious stimulation in patients during general anaesthesia

Sarén-Koivuniemi, T. J. M., Yli-Hankala, A. M. & van Gils, M., 2011, In : Computer Methods and Programs in Biomedicine. 104, 2, p. 154-160

Research output: Contribution to journalArticleScientificpeer-review

4 Citations (Scopus)

Interleukin 10 and Heart Fatty Acid-Binding Protein as Early Outcome Predictors in Patients With Traumatic Brain Injury

Lagerstedt, L., Azurmendi, L., Tenovuo, O., Katila, A. J., Takala, R. S. K., Blennow, K., Newcombe, V. F. J., Maanpää, H. R., Tallus, J., Hossain, I., Gils, M. V., Menon, D. K., Hutchinson, P. J., Zetterberg, H., Posti, J. P. & Sanchez, J. C., 2 Jun 2020, In : Frontiers in Neurology. 11, 9 p., 376.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2 Downloads (Pure)

Long-term self-monitoring of weight: A case study

Lappalainen, R., Pulkkinen, P., van Gils, M., Pärkkä, J. & Korhonen, I., 2005, In : Cognitive Behaviour Therapy. 34, 2, p. 108-114

Research output: Contribution to journalArticleScientificpeer-review

13 Citations (Scopus)

Metabolic profiles help discriminate mild cognitive impairment from dementia stage in Alzheimer's disease

Jääskeläinen, O., Hall, A., Tiainen, M., Van Gils, M., Lötjönen, J., Kangas, A. J., Helisalmi, S., Pikkarainen, M., Hallikainen, M., Koivisto, A., Hartikainen, P., Hiltunen, M., Ala-Korpela, M., Soininen, P., Soininen, H. & Herukka, S. K., 10 Mar 2020, In : Journal of Alzheimer's Disease. 74, 1, p. 277-286 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2 Citations (Scopus)

Methods for assessing adequacy of anesthesia

van Gils, M., Korhonen, I. & Yli-Hankala, A., 2002, In : Critical Reviews in Biomedical Engineering. 30, 1-3, p. 99-130

Research output: Contribution to journalArticleScientificpeer-review

11 Citations (Scopus)

Multivariate prediction of Hippocampal atrophy in Alzheimer's disease

Liedes, H., Lötjönen, J., Kortelainen, J. M., Novak, G., van Gils, M. & Gordon, M. F., 23 Apr 2019, In : Journal of Alzheimer's Disease. 68, 4, p. 1453-1468

Research output: Contribution to journalArticleScientificpeer-review

Narcotrend index indicates age-related changes during propofol induction in children

Muente, S., Klockars, J., van Gils, M., Quandt, C., Gross, M., Hiller, A. & Taivainen, T., 2008, In : Anesthesia and Analgesia. 109, 1, p. 53-59

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Novel multiparameter approach for measurement of nociception at skin incision during general anaesthesia

Rantanen, M., Yli-Hankala, A., van Gils, M., Yppärilä-Wolters, H., Takala, P., Huiku, M., Kymäläinen, M., Seitsonen, E. & Korhonen, I., 2006, In : British Journal of Anaesthesia. 96, 3, p. 367-376

Research output: Contribution to journalArticleScientificpeer-review

61 Citations (Scopus)

"OPTImAL": An ontology for patient adherence modeling in physical activity domain

Livitckaia, K., Koutkias, V., Kouidi, E., van Gils, M., Maglaveras, N. & Chouvarda, I., 25 Apr 2019, In : BMC Medical Informatics and Decision Making. 19, 1, 15 p., 92.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Predicting AD Conversion: Comparison between Prodromal AD Guidelines and Computer Assisted PredictAD Tool

Liu, Y., Mattila, J., Ruiz, M. Á. M., Paajanen, T., Koikkalainen, J., van Gils, M., Herukka, S-K., Waldemar, G., Lötjönen, J. & Soininen, H., 2013, In : PLoS ONE. 8, 2, 8 p., e55246.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
33 Citations (Scopus)

Prediction models for dementia and neuropathology in the oldest old: The Vantaa 85+ cohort study 11 Medical and Health Sciences 1109 Neurosciences

Hall, A., Pekkala, T., Polvikoski, T., van Gils, M., Kivipelto, M., Lötjönen, J., Mattila, J., Kero, M., Myllykangas, L., Mäkelä, M., Oinas, M., Paetau, A., Soininen, H., Tanskanen, M. & Solomon, A., 22 Jan 2019, In : Alzheimer's Research and Therapy. 11, 1, p. 11 11.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
5 Citations (Scopus)

Procedures for Evaluating the Adequacy of Anesthesia

van Gils, M., Korhonen, I. & Yli-Hankala, A., 1 Jan 2017, In : Critical Reviews in Biomedical Engineering. 45, 1-6, p. 187-218 32 p.

Research output: Contribution to journalArticleScientificpeer-review