Mark van Gils

  • Phone+358405583184
1993 …2020

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A Decision Support System for Diagnostics and Treatment Planning in Traumatic Brain Injury

Umer, A., Mattila, J., Liedes, H., Koikkalainen, J., Lotjonen, J., Katila, A., Frantzen, J., Newcombe, V., Tenovuo, O., Menon, D. & van Gils, M., 1 May 2019, In : IEEE Journal of Biomedical and Health Informatics. 23, 3, p. 1261-1268 8370619.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A disease state fingerprint for evaluation of Alzheimer's disease

Mattila, J., Koikkalainen, J., Virkki, A., Simonsen, A., van Gils, M., Waldemar, G., Soininen, H., Lötjönen, J. & The Alzheimer’s Disease Neuroimaging Initiative, 2011, In : Journal of Alzheimer's Disease. 27, 1, p. 163-176 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
63 Citations (Scopus)

Application of the PredictAD Decision Support Tool to a Danish Cohort of Patients with Alzheimer's Disease and Other Dementias

Simonsen, A., Mattila, J., Hejl, A-M., Garde, E., van Gils, M., Thomsen, C., Lötjönen, J., Soininen, H. & Waldemar, G., 2014, In : Dementia and Geriatric Cognitive Disorders. 37, 3-4, p. 207-213

Research output: Contribution to journalArticle

5 Citations (Scopus)

Application of the predictad software tool to predict progression in patients with mild cognitive impairment

Simonsen, A. H., Mattila, J., Hejl, A. M., Frederiksen, K. S., Herukka, S. K., Hallikainen, M., van Gils, M., Lötjönen, J., Soininen, H. & Waldemar, G., 2012, In : Dementia and Geriatric Cognitive Disorders. 34, 5-6, p. 344-350

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Assessment of surgical stress during general anaesthesia

Huiku, M., Kymäläinen, M., Takala, P., Uutela, K., Viertiö-Oja, H., Rantanen, M., van Gils, M., Korhonen, I. & Yli-Hankala, A., 2007, In : British Journal of Anaesthesia. 98, 4, p. 447-455

Research output: Contribution to journalArticle

153 Citations (Scopus)

Automatically computed rating scales from MRI for patients with cognitive disorders

Koikkalainen, J. R., Rhodius-Meester, H. F. M., Frederiksen, K. S., Bruun, M., Hasselbalch, S. G., Baroni, M., Mecocci, P., Vanninen, R., Remes, A., Soininen, H., van Gils, M., van der Flier, W. M., Scheltens, P., Barkhof, F., Erkinjuntti, T. & Lötjönen, J. M. P., 1 Sep 2019, In : European Radiology. 29, 9, p. 4937-4947

Research output: Contribution to journalArticle

3 Citations (Scopus)

Automatic MRI Quantifying Methods in Behavioral-Variant Frontotemporal Dementia Diagnosis

Cajanus, A., Hall, A., Koikkalainen, J., Solje, E., Tolonen, A., Urhemaa, T., Liu, Y., Haanpää, R. M., Hartikainen, P., Helisalmi, S., Korhonen, V., Rueckert, D., Hasselbalch, S., Waldemar, G., Mecocci, P., Vanninen, R., van Gils, M., Soininen, H., Lötjönen, J. & Remes, A. M., 3 Apr 2018, In : Dementia and Geriatric Cognitive Disorders Extra. 8, 1, p. 51-59

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Biosignal processing methods to guide cardiac patients to perform safe and beneficial exercise for rehabilitation

Runtti, H., Honka, A., Chouvarda, I., Michail, E., Kokonozi, A., Merilahti, J., Pärkkä, J. & van Gils, M., 2013, In : International Journal of Bioelectromagnetism. 15, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

Open Access

Building the IMPROVE data library

Korhonen, I., Ojaniemi, J., Nieminen, K., van Gils, M., Heikelä, A. & Kari, A., 1997, In : IEEE Engineering in Medicine and Biology Magazine. 16, 6, p. 25-32

Research output: Contribution to journalArticle

30 Citations (Scopus)

Collecting EEG signals in the IMPROVE data library

Thomsen, C., Grade, J., Nieminen, K., Langford, R., Ghosh, R., Jensen, K., van Gils, M., Rosenfalck, A., Prior, P. & White, S., 1997, In : IEEE Engineering in Medicine and Biology Magazine. 16, 6, p. 33-40

Research output: Contribution to journalArticle

17 Citations (Scopus)

Comparison of train-of-four ratios measured with Datex-Ohmeda's M-NMT MechanoSensor and M-NMT ElectroSensor

Salminen, J., van Gils, M., Paloheimo, M. & Yli-Hankala, A., 2016, In : Journal of Clinical Monitoring and Computing. 30, 3, p. 295-300

Research output: Contribution to journalArticleScientificpeer-review

4 Citations (Scopus)

Consistensy of Muistikko web-based cognitive test while performed at clinic and at home

Lötjönen, J., Paajanen, T., Bruun, M., Mahdiani, S., Baroni, M., Rhodius-Meester, H., Herukka, S-K., Lemstra, A. W., Pikkarainen, M., Hänninen, T., van Gils, M., Hasselbalch, S., Mecocci, P., Remes, A. M., van der Flier, W. M. & Soininen, H., 1 Jul 2018, In : Alzheimer's and Dementia. 14, 7, p. 418-418 P1-328.

Research output: Contribution to journalArticle

Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury

Posti, J. P., Takala, R. S. K., Lagerstedt, L., Dickens, A. M., Hossain, I., Mohammadian, M., Ala-Seppälä, H., Frantzén, J., van Gils, M., Hutchinson, P. J., Katila, A. J., Maanpaä, H. R., Menon, D. K., Newcombe, V. F., Tallus, J., Hrusovsky, K., Wilson, D. H., Gill, J., Sanchez, J. C., Tenovuo, O. & 2 others, Zetterberg, H. & Blennow, K., 15 Jul 2019, In : Journal of Neurotrauma. 36, 14, p. 2178-2189

Research output: Contribution to journalArticle

5 Citations (Scopus)

Design and application of a generic clinical decision support system for multiscale data

Mattila, J., Koikkalainen, J., Virkki, A., van Gils, M. & Lötjönen, J., 2012, In : IEEE Transactions on Biomedical Engineering. 59, 1, p. 234-240

Research output: Contribution to journalArticle

32 Citations (Scopus)

Detecting frontotemporal dementia syndromes using MRI biomarkers

Bruun, M., Koikkalainen, J., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., van Gils, M., Soininen, H., Remes, A., Hartikainen, P., Waldemar, G., Mecocci, P., Barkhof, F., Pijnenburg, Y., van der Flier, W. M., Hasselbalch, S. G., Lötjönen, J. & Frederiksen, K. S., 4 Feb 2019, In : NeuroImage: Clinical. 22, p. 101711 101711.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Detecting frontotemporal dementia using a novel MRI imaging biomarker: The anterior versus posterior index

Bruun, M., Koikkalainen, J., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., van Gils, M., Soininen, H., Remes, A. M., Waldemar, G., Mecocci, P., van der Flier, W. M., Hasselbalch, S., Jyrki, L. & Frederiksen, K. S., 1 Jul 2018, In : Alzheimer's and Dementia. 14, 7, p. 821-822 P2-350.

Research output: Contribution to journalArticle

Open Access

Different combinations of diagnostic tests discriminate specific subtypes of dementia

Rhodius-Meester, H. F. M., Bruun, M., Baroni, M., Gjerum, L., Remes, A. M., Urhemaa, T., Tolonen, A., Rueckert, D., van Gils, M., Lemstra, E., Barkhof, F., Frederiksen, K. S., Waldemar, G., Scheltens, P., Soininen, H., Mecocci, P., Koikkalainen, J., Lötjönen, J. & van der Flier, W. M., 1 Jul 2018, In : Alzheimer's and Dementia. 10, 7, p. 820-821 P2-349.

Research output: Contribution to journalArticle

Disease-related determinants are associated with mortality in dementia due to Alzheimer's disease

Rhodius-Meester, H. F. M., Liedes, H., Koene, T., Lemstra, A. W., Teunissen, C. E., Barkhof, F., Scheltens, P., van Gils, M., Lötjönen, J. & van der Flier, W. M., 2018, In : Alzheimer's Research and Therapy. 10, 1, 23.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Early Levels of Glial Fibrillary Acidic Protein and Neurofilament Light Protein in Predicting the Outcome of Mild Traumatic Brain Injury

Hossain, I., Mohammadian, M., Takala, R. S. K., Tenovuo, O., Lagerstedt, L., Ala-Seppälä, H. M., Frantzén, J., van Gils, M., Hutchinson, P. J., Katila, A. J., Maanpää, H-R., Menon, D., Newcombe, V., Tallus, J., Hrusovsky, K., Wilson, D., Blennow, K., Sanchez, J-C., Zetterberg, H. & Posti, J. P., 15 May 2019, In : Journal of Neurotrauma. 36, 10, p. 1551-1560

Research output: Contribution to journalArticleScientificpeer-review

2 Citations (Scopus)

EEG spectral entropy, heart rate, photoplethysmography and motor responses to skin incision during sevoflurane anaesthesia

Seitsonen, E., Korhonen, I., van Gils, M., Huiku, M., Lötjönen, J., Korttila, K. & Yli-Hankala, A., 2005, In : Acta Anaesthesiologica Scandinavica. 49, 3, p. 284-292

Research output: Contribution to journalArticle

69 Citations (Scopus)

Entropy is more resistant to artifacts than bispectral index in brain-dead organ donors

Wennervirta, J., Salmi, T., Hynynen, M., Yli-Hankala, A., Koivusalo, A-M., van Gils, M., Pöyhiä, R. & Vakkuri, A., 2007, In : Intensive Care Medicine. 33, 1, p. 133-136

Research output: Contribution to journalArticle

25 Citations (Scopus)

Evaluating combinations of diagnostic tests to discriminate different dementia types

Bruun, M., Rhodius-Meester, H. F. M., Koikkalainen, J., Baroni, M., Gjerum, L., Lemstra, A. W., Barkhof, F., Remes, A. M., Urhemaa, T., Tolonen, A., Rueckert, D., van Gils, M., Frederiksen, K. S., Waldemar, G., Scheltens, P., Mecocci, P., Soininen, H., Lötjönen, J., Hasselbalch, S. G. & van der Flier, W. M., 1 Jan 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 509-518 10 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Framework for biosignal interpretation in intensive care and anesthesia

Saranummi, N., Korhonen, I., Van Gils, M. & Kari, A., 1 Dec 1997, In : Methods of Information in Medicine. 36, 4-5, p. 340-344

Research output: Contribution to journalArticle

3 Citations (Scopus)

Glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 are not specific biomarkers for mild CT-negative traumatic brain injury

Posti, J. P., Hossain, I., Takala, R. S. K., Liedes, H., Newcombe, V., Outtrim, J., Katila, A. J., Frantzén, J., Ala-Seppälä, H., Coles, J. P., Kyllönen, A., Maanpää, H-R., Tallus, J., Hutchinson, P. J., van Gils, M., Menon, D. K. & Tenovuo, O., 1 Apr 2017, In : Journal of Neurotrauma. 34, 7, p. 1427-1438 12 p.

Research output: Contribution to journalArticleScientificpeer-review

29 Citations (Scopus)

Glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 as outcome predictors in traumatic brain injury

Takala, R. S. K., Posti, J. P., Runtti, H., Newcombe, V. F., Outtrim, J., Katila, A. J., Frantzén, J., Ala-Seppälä, H., Kyllönen, A., Maanpää, H-R., Tallus, J., Hossain, M. I., Coles, J. P., Hutchinson, P., van Gils, M., Menon, D. K. & Tenovuo, O., 2016, In : World Neurosurgery. 87, p. 8-20

Research output: Contribution to journalArticleScientificpeer-review

36 Citations (Scopus)

Graphical Tasks to Measure Upper Limb Function in Patients with Parkinson's Disease: Validity and Response to Dopaminergic Medication

Smits, E. J., Tolonen, A. J., Cluitmans, L., van Gils, M., Zietsma, R. C., Borgemeester, R. W. K., van Laar, T. & Maurits, N. M., 1 Jan 2017, In : IEEE Journal of Biomedical and Health Informatics. 21, 1, p. 283-289

Research output: Contribution to journalArticle

10 Citations (Scopus)

Health monitoring in the home of the future

Korhonen, I., Pärkkä, J. & van Gils, M., 2003, In : IEEE Engineering in Medicine and Biology Magazine. 22, 3, p. 66-73

Research output: Contribution to journalArticle

339 Citations (Scopus)

Heart rate variability responses to skin incision in 0.8 MAC sevoflurane anaesthesia

Korhonen, I., Seitsonen, E., van Gils, M., Korttila, K. & Yli-Hankala, A., 2003, In : International Journal of Bioelectromagnetism. 5, 1, p. 240-241

Research output: Contribution to journalArticle

Open Access

Identification of adequate neurally adjusted ventilatory assist (NAVA) during systematic increases in the NAVA level

Ververidis, D., van Gils, M., Passath, C., Takala, J. & Brander, L., 2011, In : IEEE Transactions on Biomedical Engineering. 58, 9, p. 2598-2606

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Identification of peak V in brainstem auditory evoked potentials with neural networks

Habraken, J. B. A., van Gils, M. J. & Cluitmans, P. J. M., 1 Jan 1993, In : Computers in Biology and Medicine. 23, 5, p. 369-380

Research output: Contribution to journalArticle

15 Citations (Scopus)

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study

Bruun, M., Frederiksen, K. S., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., Koikkalainen, J., Urhemaa, T., Tolonen, A., van Gils, M., Tong, T., Guerrero, R., Rueckert, D., Dyremose, N., Bo Andersen, B., Simonsen, A. H., Lemstra, A. W., Hallikainen, M., Kurl, S., Herukka, S-K., Remes, A. M. & 6 others, Waldemar, G., Soininen, H., Mecocci, P., van der Flier, W. M., Lötjönen, J. & Hasselbalch, S. G., Feb 2019, In : Current Alzheimer Research. 16, 2, p. 91-101

Research output: Contribution to journalArticle

3 Citations (Scopus)

Impact of a clinical decision support tool on prediction of progression in early-stage dementia: A prospective validation study

Bruun, M., Frederiksen, K. S., Rhodius-Meester, H. F. M., Baroni, M., Gjerum, L., Koikkalainen, J., Urhemaa, T., Tolonen, A., van Gils, M., Rueckert, D., Dyremose, N., Andersen, B. B., Lemstra, A. W., Hallikainen, M., Kurl, S., Herukka, S. K., Remes, A. M., Waldemar, G., Soininen, H., Mecocci, P. & 3 others, Van Der Flier, W. M., Lötjönen, J. & Hasselbalch, S. G., 20 Mar 2019, In : Alzheimer's Research and Therapy. 11, 1, 25.

Research output: Contribution to journalArticle

Open Access

Improved classification of Alzheimer's disease data via removal of nuisance variability

Koikkalainen, J., Pölönen, H., Mattila, J., van Gils, M., Soininen, H. & Lötjönen, J., 2012, In : PLoS ONE. 7, 2, 12 p., e31112.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
33 Citations (Scopus)

Increased variation of the response index of nociception during noxious stimulation in patients during general anaesthesia

Sarén-Koivuniemi, T. J. M., Yli-Hankala, A. M. & van Gils, M., 2011, In : Computer Methods and Programs in Biomedicine. 104, 2, p. 154-160

Research output: Contribution to journalArticle

4 Citations (Scopus)

Long-term self-monitoring of weight: A case study

Lappalainen, R., Pulkkinen, P., van Gils, M., Pärkkä, J. & Korhonen, I., 2005, In : Cognitive Behaviour Therapy. 34, 2, p. 108-114

Research output: Contribution to journalArticle

13 Citations (Scopus)

Methods for assessing adequacy of anesthesia

van Gils, M., Korhonen, I. & Yli-Hankala, A., 2002, In : Critical Reviews in Biomedical Engineering. 30, 1-3, p. 99-130

Research output: Contribution to journalArticle

11 Citations (Scopus)

Multivariate prediction of Hippocampal atrophy in Alzheimer's disease

Liedes, H., Lötjönen, J., Kortelainen, J. M., Novak, G., van Gils, M. & Gordon, M. F., 23 Apr 2019, In : Journal of Alzheimer's Disease. 68, 4, p. 1453-1468

Research output: Contribution to journalArticle

Narcotrend index indicates age-related changes during propofol induction in children

Muente, S., Klockars, J., van Gils, M., Quandt, C., Gross, M., Hiller, A. & Taivainen, T., 2008, In : Anesthesia and Analgesia. 109, 1, p. 53-59

Research output: Contribution to journalArticle

Open Access

Novel multiparameter approach for measurement of nociception at skin incision during general anaesthesia

Rantanen, M., Yli-Hankala, A., van Gils, M., Yppärilä-Wolters, H., Takala, P., Huiku, M., Kymäläinen, M., Seitsonen, E. & Korhonen, I., 2006, In : British Journal of Anaesthesia. 96, 3, p. 367-376

Research output: Contribution to journalArticle

60 Citations (Scopus)

"OPTImAL": An ontology for patient adherence modeling in physical activity domain

Livitckaia, K., Koutkias, V., Kouidi, E., van Gils, M., Maglaveras, N. & Chouvarda, I., 25 Apr 2019, In : BMC Medical Informatics and Decision Making. 19, 1, 15 p., 92.

Research output: Contribution to journalArticle

Open Access

Predicting AD Conversion: Comparison between Prodromal AD Guidelines and Computer Assisted PredictAD Tool

Liu, Y., Mattila, J., Ruiz, M. Á. M., Paajanen, T., Koikkalainen, J., van Gils, M., Herukka, S-K., Waldemar, G., Lötjönen, J. & Soininen, H., 2013, In : PLoS ONE. 8, 2, 8 p., e55246.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

Prediction models for dementia and neuropathology in the oldest old: The Vantaa 85+ cohort study 11 Medical and Health Sciences 1109 Neurosciences

Hall, A., Pekkala, T., Polvikoski, T., van Gils, M., Kivipelto, M., Lötjönen, J., Mattila, J., Kero, M., Myllykangas, L., Mäkelä, M., Oinas, M., Paetau, A., Soininen, H., Tanskanen, M. & Solomon, A., 22 Jan 2019, In : Alzheimer's Research and Therapy. 11, 1, p. 11 11.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Procedures for Evaluating the Adequacy of Anesthesia

van Gils, M., Korhonen, I. & Yli-Hankala, A., 1 Jan 2017, In : Critical Reviews in Biomedical Engineering. 45, 1-6, p. 187-218 32 p.

Research output: Contribution to journalArticle

Propofol versus alfentanil to prevent movement responses during uterine curettage

Seitsonen, E. R. J., Cohen-Laroque, E-S., van Gils, M., Korttila, K. T., Neuvonen, P. J. & Yli-Hankala, A. M., 2007, In : Acta Anaesthesiologica Scandinavica. 51, 6, p. 751-758

Research output: Contribution to journalArticle

4 Citations (Scopus)

Quantification of epileptiform electroencephalographic activity during sevoflurane mask induction

Särkelä, M. O. K., Ermes, M., van Gils, M., Yli-Hankala, A. M., Jäntti, V. H. & Vakkuri, A. P., 2007, In : Anesthesiology. 107, 6, p. 928-938

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Quantitative EEG Parameters for Prediction of Outcome in Severe Traumatic Brain Injury: Development Study

Tolonen, A., Särkelä, M., Takala, R., Katila, A., Frantzén, J., Posti, J., Müller, M., van Gils, M. & Tenovuo, O., 2018, In : Clinical EEG and Neuroscience. 49, 4, p. 248-257 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Quantitative Evaluation of Disease Progression in a Longitudinal Mild Cognitive Impairment Cohort

Runtti, H., Mattila, J., van Gils, M., Koikkalainen, J., Soininen, H. & Lötjönen, J., 2014, In : Journal of Alzheimer's Disease. 39, 1, p. 49-61

Research output: Contribution to journalArticle

15 Citations (Scopus)

Relationship of Psychological and Physiological Variables in Long-Term Self-Monitored Data During Work Ability Rehabilitation Program

Pärkkä, J., Merilahti, J., Mattila, E. M., Malm, E., Antila, K., Tuomisto, M. T., Saarinen, A. V., van Gils, M. & Korhonen, I., 2009, In : IEEE Transactions on Information Technology in Biomedicine. 13, 2, p. 141-151

Research output: Contribution to journalArticle

21 Citations (Scopus)

Reproducibility of standardized fine motor control tasks and age effects in healthy adults

Smits, E. J., Tolonen, A. J., Cluitmans, L., van Gils, M., Zietsma, R. C., Tijssen, M. A. J. & Maurits, N. M., 1 Jan 2018, In : Measurement. 114, Jan, p. 177-184

Research output: Contribution to journalArticle

1 Citation (Scopus)