Markku Saloheimo

  • Phone+358405760892
1987 …2018

Research output per year

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Research Output

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Open Access
19 Citations (Scopus)

Activation mechanisms of the HAC1-mediated unfolded protein response in filamentous fungi

Saloheimo, M., Valkonen, M. & Penttilä, M., 1 Jan 2003, In : Molecular Microbiology. 47, 4, p. 1149-1161 13 p.

Research output: Contribution to journalArticleScientificpeer-review

101 Citations (Scopus)

A lignin peroxidase-encoding cDNA from the white-rot fungus Phlebia radiata: Characterization and expression in Trichoderma reesei

Saloheimo, M., Barajas, V., Niku-Paavola, M-L. & Knowles, J., 1989, In : Gene. 85, 2, p. 343-351

Research output: Contribution to journalArticleScientificpeer-review

62 Citations (Scopus)

A new crystal form of Aspergillus oryzae catechol oxidase and evaluation of copper site structures in coupled binuclear copper enzymes

Penttinen, L., Rutanen, C., Saloheimo, M., Kruus, K., Rouvinen, J. & Hakulinen, N., 1 May 2018, In : PLoS ONE. 13, 5, e0196691.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2 Citations (Scopus)

Array comparative genomic hybridization analysis of Trichoderma reesei strains with enhanced cellulase production properties

Vitikainen, M., Arvas, M., Pakula, T., Oja, M., Penttilä, M. & Saloheimo, M., 19 Jul 2010, In : BMC Genomics. 11, 441.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
60 Citations (Scopus)

cDNA cloning of a Trichoderma reesei cellulase and demonstration of endoglucanase activity by expression in yeast

Saloheimo, M., Nakari-Setälä, T., Tenkanen, M. & Penttilä, M., 1997, In : FEBS Journal. 249, 2, p. 584-591

Research output: Contribution to journalArticleScientificpeer-review

Open Access
153 Citations (Scopus)

cDNA encoding protein 0-mannosyltransferase from the filamentous fungus Trichoderma reesei; functional equivalence to Saccharomyces cerevisiae PMT2

Zakrzewska, A., Migdalski, A., Saloheimo, M., Penttilä, M., Palamarczyk, G. & Kruszewska, J., 2003, In : Current Genetics. 43, 1, p. 11-16

Research output: Contribution to journalArticleScientificpeer-review

cDNA encoding protein O-mannosyltransferase from the filamentous fungus Trichoderma reesei: functional equivalence to Saccharomyces cerevisiae PMT2

Zakrzewska, A., Migdalski, A., Saloheimo, M., Penttila, M. E., Palamarczyk, G. & Kruszewska, J. S., 1 Apr 2003, In : Current Genetics. 43, 1, p. 11-16 6 p.

Research output: Contribution to journalArticleScientificpeer-review

18 Citations (Scopus)

Characterisation of two 14-3-3 genes from Trichoderma reesei: Interactions with yeast secretory pathway components

Vasara, T., Keränen, S., Penttilä, M. & Saloheimo, M., 12 Jun 2002, In : Biochimica et Biophysica Acta: Molecular Cell Research. 1590, 1-3, p. 27-40 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
20 Citations (Scopus)

Characterization of a birch (Betula pendula Roth.) embryogenic gene, BP8

Puupponen-Pimiä, R., Saloheimo, M., Vasara, T., Ra, R., Gaugecz, J., Kurten, U., Knowles, J., Keränen, S. & Kauppinen, V., 1993, In : Plant Molecular Biology. 23, 2, p. 423 - 428 6 p.

Research output: Contribution to journalArticleScientificpeer-review

17 Citations (Scopus)

Characterization of Melanocarpus albomyces steryl esterase produced in Trichoderma reesei and modification of fibre products with the enzyme

Kontkanen, H., Saloheimo, M., Pere, J., Miettinen-Oinonen, A. & Reinikainen, T., 2006, In : Applied Microbiology and Biotechnology. 72, 4, p. 696-704 9 p.

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)
26 Citations (Scopus)

Characterization of the laccase and its gene from the white-rot fungus Phlebia radiata

Saloheimo, M., Karhunen, E., Niku-Paavola, M-L. & Knowles, J., 1990, In : Kemia-Kemi. 17, 10B, p. 967

Research output: Contribution to journalArticleProfessional

Cloning and characterization of a novel acidic cutinase from Sirococcus conigenus

Nyyssölä, A., Pihlajaniemi, V., Häkkinen, M., Kontkanen, H., Saloheimo, M. & Nakari-Setälä, T., 1 Jan 2014, In : Applied Microbiology and Biotechnology. 98, 8, p. 3639-3650 12 p.

Research output: Contribution to journalArticleScientificpeer-review

13 Citations (Scopus)

Cloning and expression of a Melanocarpus albomyces steryl esterase gene in Pichia pastoris and Trichoderma reesei

Kontkanen, H., Reinikainen, T. & Saloheimo, M., 2006, In : Biotechnology and Bioengineering. 94, 3, p. 407-415 9 p.

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)

Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae

Arvas, M., Pakula, T., Lanthaler, K., Saloheimo, M., Valkonen, M., Suortti, T., Robson, G. & Penttilä, M., 20 Mar 2006, In : BMC Genomics. 7, 32.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
76 Citations (Scopus)
Open Access
6 Citations (Scopus)

Comparison of protein coding gene contents of the fungal phyla Pezizomycotina and Saccharomycotina

Arvas, M., Kivioja, T., Mitchell, A., Saloheimo, M., Ussery, D., Penttilä, M. & Oliver, S., 17 Sep 2007, In : BMC Genomics. 8, 23 p., 325.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
38 Citations (Scopus)

Correlation of gene expression and protein production rate: a system wide study

Arvas, M., Pakula, T., Smit, B., Rautio, J., Koivistoinen, H., Jouhten, P., Lindfors, E., Wiebe, M., Penttilä, M. & Saloheimo, M., 20 Dec 2011, In : BMC Genomics. 12, 616.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
43 Citations (Scopus)

Crystal structure of a laccase from Melanocarpus albomyces with an intact trinuclear copper site

Hakulinen, N., Kiiskinen, L-L., Kruus, K., Saloheimo, M., Paananen, A., Koivula, A. & Rouvinen, J., 2002, In : Nature Structural Biology. 9, 8, p. 601-605

Research output: Contribution to journalArticleScientificpeer-review

290 Citations (Scopus)

Detecting novel genes with sparse arrays

Arvas, M., Haiminen, N., Smit, B., Rautio, J., Vitikainen, M., Wiebe, M., Martinez, D., Chee, C., Kunkel, J., Sanchez, C., Nelson, M. A., Pakula, T., Saloheimo, M., Penttilä, M. & Kivioja, T., 1 Nov 2010, In : Gene. 467, 1-2, p. 41-51

Research output: Contribution to journalArticleScientificpeer-review

9 Citations (Scopus)

Development of a low-cost cellulase production process using Trichoderma reesei for Brazilian biorefineries

Ellilä, S., Fonseca, L., Uchima, C., Cota, J., Goldman, G. H., Saloheimo, M., Sacon, V. & Siika-Aho, M., 2017, In : Biotechnology for Biofuels. 10, 1, p. 30

Research output: Contribution to journalArticleScientificpeer-review

Open Access
41 Citations (Scopus)

Directing enzymatic cross-linking activity to the air-water interface by a fusion protein approach

Paananen, A., Ercili Cura, D., Saloheimo, M., Lantto, R. & Linder, M., 2013, In : Soft Matter. 9, 5, p. 1612-1619 8 p.

Research output: Contribution to journalArticleScientificpeer-review

9 Citations (Scopus)

Discovery of a new tyrosinase-like enzyme family lacking a C-terminally processed domain: Production and characterization of an Aspergillus oryzae catechol oxidase

Gasparetti, C., Faccio, G., Arvas, M., Buchert, J., Saloheimo, M. & Kruus, K., 2010, In : Applied Microbiology and Biotechnology. 86, 1, p. 213-226 14 p.

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)

Dolichol phosphate mannose synthase from the filamentous fungus Trichoderma reesei belongs to the human and Schizosaccharomyces pombe class of the enzyme

Kruszewska, J. S., Saloheimo, M., Migdalski, A., Orlean, P., Penttilä, M. & Palamarczyk, G., 1 Jan 2000, In : Glycobiology. 10, 10, p. 983-991 9 p.

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)
122 Citations (Scopus)

EGIII, a new endoglucanase from Trichoderma reesei: the characterization of both gene and enzyme

Saloheimo, M., Lehtovaara, P., Penttilä, M., Teeri, T. T., Ståhlberg, J., Johansson, G., Pettersson, G., Claeyssens, M., Tomme, P. & Knowles, J. K. C., 15 Mar 1988, In : Gene. 63, 1, p. 11-21 11 p.

Research output: Contribution to journalArticleScientificpeer-review

261 Citations (Scopus)

Enabling low cost biopharmaceuticals: A systematic approach to delete proteases from a well-known protein production host trichoderma reesei

Landowski, C. P., Huuskonen, A., Wahl, R., Westerholm-Parvinen, A., Kanerva, A., Hänninen, A-L., Salovuori, N., Penttilä, M., Natunen, J., Ostermeier, C., Helk, B., Saarinen, J. & Saloheimo, M., 2015, In : PLoS ONE. 10, 8, e0134723.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
24 Citations (Scopus)

Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei

Landowski, C. P., Mustalahti, E., Wahl, R., Croute, L., Sivasiddarthan, D., Westerholm-Parvinen, A., Sommer, B., Ostermeier, C., Helk, B., Saarinen, J. & Saloheimo, M., 2016, In : Microbial Cell Factories. 15, 1, 104.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
10 Citations (Scopus)

Enzymatic properties and intracellular localization of the novel Trichoderma reesei β-glucosidase BGLII (Cel1A)

Saloheimo, M., Kuja-Panula, J., Ylösmäki, E., Ward, M. & Penttilä, M., 1 Sep 2002, In : Applied and Environmental Microbiology. 68, 9, p. 4546-4553

Research output: Contribution to journalArticleScientificpeer-review

127 Citations (Scopus)

Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure

Andberg, M., Hakulinen, N., Auer, S., Saloheimo, M., Koivula, A., Rouvinen, J. & Kruus, K., 2009, In : FEBS Journal. 276, 21, p. 6285-6300 16 p.

Research output: Contribution to journalArticleScientificpeer-review

59 Citations (Scopus)

Eukaryotic protein production in designed storage organelles

Torrent, M., Llompart, B., Lasserre-Ramassamy, S., Llop-Tous, I., Bastida, M., Marzabal, P., Westerholm-Parvinen, A., Saloheimo, M., Heifetz, P. B. & Ludevid, M. D., 2009, In : BMC Biology. 7, 5.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
91 Citations (Scopus)

Experimental and bioinformatic investigation of the proteolytic degradation of the C-terminal domain of a fungal tyrosinase

Faccio, G., Arvas, M., Thöny-Meyer, L. & Saloheimo, M., 2013, In : Journal of Inorganic Biochemistry. 121, p. 37-45 9 p.

Research output: Contribution to journalArticleScientificpeer-review

10 Citations (Scopus)

Exploring laccase-like multicopper oxidase genes from the ascomycete Trichoderma reesei: A functional, phylogenetic and evolutionary study

Levasseur, A., Saloheimo, M., Navarro, D., Andberg, M., Pontarotti, P., Kruus, K. & Record, E., 2010, In : BMC biochemistry. 11, 32

Research output: Contribution to journalArticleScientificpeer-review

Open Access
31 Citations (Scopus)

Expression in Trichoderma reesei and characterisation of a thermostable family 3 β-glucosidase from the moderately thermophilic fungus Talaromyces emersonii

Murray, P., Aro, N., Collins, C., Grassick, A., Penttilä, M., Saloheimo, M. & Tuohy, M., 1 Dec 2004, In : Protein Expression and Purification. 38, 2, p. 248-257 10 p.

Research output: Contribution to journalArticleScientificpeer-review

108 Citations (Scopus)

Expression of Melanocarpus albomyces laccase in Trichoderma reesei and characterization of the purified enzyme

Kiiskinen, L-L., Kruus, K., Bailey, M., Ylösmäki, E., Siika-aho, M. & Saloheimo, M., 2004, In : Microbiology. 150, p. 3065 - 3074 10 p.

Research output: Contribution to journalArticleScientificpeer-review

145 Citations (Scopus)

Expression of the Trichoderma reesei Tyrosinase 2 in Pichia pastoris: Isotopic labeling and physicochemical characterization

Westerholm-Parvinen, A., Selinheimo, E., Boer, H., Kalkkinen, N., Mattinen, M. & Saloheimo, M., 2007, In : Protein Expression and Purification. 55, 1, p. 147-158

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)

Expression of Two Novel β-Glucosidases from Chaetomium atrobrunneum in Trichoderma reesei and Characterization of the Heterologous Protein Products

Colabardini, A. C., Valkonen, M., Huuskonen, A., Siika-aho, M., Koivula, A., Goldman, G. H. & Saloheimo, M., 1 Dec 2016, In : Molecular Biotechnology. 58, 12, p. 821-831 11 p.

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)

Expression of two Trichoderma reesei endoglucanases in the yeast Saccharomyces cerevisiae

Penttilä, M., Andre, L., Saloheimo, M., Lehtovaara, P. & Knowles, J., 1987, In : Yeast. 3, 3, p. 175-185

Research output: Contribution to journalArticleScientificpeer-review

111 Citations (Scopus)

Genetic modification of carbon catabolite repression in Trichoderma reesei for improved protein production

Nakari-Setälä, T., Paloheimo, M., Kallio, J., Vehmaanperä, J., Penttilä, M. & Saloheimo, M., 1 Jul 2009, In : Applied and Environmental Microbiology. 75, 14, p. 4853-4860 8 p.

Research output: Contribution to journalArticleScientificpeer-review

108 Citations (Scopus)

Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)

Martinez, D., Berka, R. M., Henrissat, B., Saloheimo, M., Arvas, M., Baker, S. E., Chapman, J., Chertkov, O., Coutinho, P. M., Cullen, D., Danchin, E. G. J., Grigoriev, I. V., Harris, P., Jackson, M., Kubicek, C. P., Han, C. S., Ho, I., Larrondo, L. F., de Leon, A. L., Magnuson, J. K. & 26 others, Merino, S., Misra, M., Nelson, B., Putnam, N., Robbertse, B., Salamov, A. A., Schmoll, M., Terry, A., Thayer, N., Westerholm-Parvinen, A., Schoch, C. L., Yao, J., Barabote, R., Barbote, R., Nelson, M. A., Detter, C., Bruce, D., Kuske, C. R., Xie, G., Richardson, P., Rokhsar, D. S., Lucas, S. M., Rubin, E. M., Dunn-Coleman, N., Ward, M. & Brettin, T. S., May 2008, In : Nature Biotechnology. 26, 5, p. 553-560 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
727 Citations (Scopus)

Genome-wide analysis of protein production physiology in the filamentous fungus Trichoderma reesei

Saloheimo, M., Pakula, T., Arvas, M., Rautio, J. & Penttilä, M., 2006, In : Microbial Cell Factories. 5, Suppl. 1

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Heterologous production of a ligninolytic enzyme: Expression of the Phlebia radiata laccase gene in Trichoderma reesei

Saloheimo, M. & Niku-Paavola, M-L., 1991, In : Bio/Technology. 9, 10, p. 987 - 990 4 p.

Research output: Contribution to journalArticleScientificpeer-review

75 Citations (Scopus)

Homologous expression and characterization of Cel61A (EG IV) of Trichoderma reesei

Karlsson, J., Saloheimo, M., Siika-Aho, M., Tenkanen, M., Penttilä, M. & Tjerneld, F., 1 Dec 2001, In : European Journal of Biochemistry. 268, 24, p. 6498-6507 10 p.

Research output: Contribution to journalArticleScientificpeer-review

103 Citations (Scopus)

Improvement of Foreign-Protein Production in Aspergillus niger var. awamori by Constitutive Induction of the Unfolded-Protein Response

Valkonen, M., Ward, M., Wang, H., Penttilä, M. & Saloheimo, M., 1 Dec 2003, In : Applied and Environmental Microbiology. 69, 12, p. 6979-6986 8 p.

Research output: Contribution to journalArticleScientificpeer-review

81 Citations (Scopus)

Influence of growth temperature on the production of antibody Fab fragments in different microbes: A host comparative analysis

Dragosits, M., Frascotti, G., Bernard-Granger, L., Vázquez, F., Giuliani, M., Baumann, K., Rodríguez-Carmona, E., Tokkanen, J., Parrilli, E., Wiebe, M. G., Kunert, R., Maurer, M., Gasser, B., Sauer, M., Branduardi, P., Pakula, T., Saloheimo, M., Penttilä, M., Ferrer, P., Luisa Tutino, M. & 3 others, Villaverde, A., Porro, D. & Mattanovich, D., 1 Jan 2011, In : Biotechnology Progress. 27, 1, p. 38-46

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)

Interactions of the Trichoderma reesei rho3 with the secretory pathway in yeast and T. reesei

Vasara, T., Salusjärvi, L., Raudaskoski, M., Keränen, S., Penttilä, M. & Saloheimo, M., 1 Dec 2001, In : Molecular Microbiology. 42, 5, p. 1349-1361 13 p.

Research output: Contribution to journalArticleScientificpeer-review

14 Citations (Scopus)

Intracellular protein production in Trichoderma reesei (Hypocrea jecorina) with hydrophobin fusion technology

Mustalahti, E., Saloheimo, M. & Joensuu, J., 2013, In : New Biotechnology. 30, 2, p. 262-268 7 p.

Research output: Contribution to journalArticleScientificpeer-review

15 Citations (Scopus)

Isolation and analysis of functional homologues of the secretion-related SAR1 gene of Saccharomyces cerevisiae from Aspergillus niger and Trichoderma reesei

Veldhuisen, G., Saloheimo, M., Fiers, M. A., Punt, P. J., Contreras, R., Penttilä, M. & Van Den Hondel, C. A. M. J. J., 27 Nov 1997, In : Molecular and General Genetics. 256, 4, p. 446-455 10 p.

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)

Isolation and structural analysis of the laccase gene from the lignin degrading fungus Phlebia radiata

Saloheimo, M., Niku-Paavola, M-L. & Knowles, J., 1991, In : Journal of General Microbiology. 137, 7, p. 1537 - 1544 8 p.

Research output: Contribution to journalArticleScientificpeer-review

121 Citations (Scopus)