Projects per year
Personal profile
Research interests
I work as the person in charge of the VTT Industrial Biotechnology Automation Platform, a cutting-edge facility dedicated to advancing high-throughput microbial strain development and bioprocessing for industrial biotechnology applications. Our platform integrates advanced technologies to automate and accelerate various stages of strain engineering, screening, and fermentation. Our instruments include:
- Screening and molecular biology automation systems (Beckman Coulter and Tecan Fluent 780) capable of high-throughput microbial candidate selection and flexible genetic manipulation workflows, providing robust and efficient support for diverse experimental needs.
- Microbioreactors (Biolector Pro and II, m2p-labs) enabling detailed physiological studies under controlled conditions, and
- A high-throughput bioprocess system (ambr250, Sartorius Stedim) for scaling up fermentation processes and optimizing bioprocess parameters.
These resources enable the platform to support a broad spectrum of projects, from constructing novel microbial strains to optimizing production processes for industrial enzymes, proteins, and other biochemicals.
In 2025, I began my doctoral studies at Aalto University, specializing in Industrial Biotechnology. My research will focus on enhancing protein production in the filamentous fungus Trichoderma reesei, a widely used host in industrial protein production. Specifically, I aim to:
- Identify genetic targets affecting protein production,
- Develop novel genetic engineering strategies to boost productivity, and
- Research material proteins to improve yields and scalability.
The ultimate goal of my work is to contribute to the development of more efficient and sustainable production systems, supporting the transition to biotechnology-based production of material proteins. I am passionate about leveraging automation and biotechnology to address industrial challenges and drive innovation in sustainable biomanufacturing.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Life sciences, Master, M.Sc. (Tech) in Biotechnology, Aalto University
Award Date: 29 Aug 2017
Agriculture, forestry and fishery, Bachelor, B.Sc. (Agr. & For.) in Biotechnology, University of Helsinki
Award Date: 15 Jun 2015
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 2 Active
-
FinBioFAB: Finnish BioFoundry for Advanced Biomanufacturing
Barth, D. (Manager), Nygård, Y. (PI), Koponen, T. (Participant), Girych, M. (Participant), Castillo, S. (Participant), Åkerman, M. (Participant), Lehtinen, S. (Participant), Nakari-Setälä, T. (Owner), Jäntti, J. (Participant), Healy-Rehn, M. (Participant), Laukkanen, A. (Participant), Aro, N. (Participant), Hentula, M. (Participant), Tenkanen, T. (Participant), Choo, H. (Participant) & Nguyen, T. (Participant)
1/01/25 → 31/12/29
Project: Business Finland project
-
BIOS: The bio-intelligent DBTL cycle, a key enabler catalysing the industrial transformation towards sustainable biomanufacturing
Blomberg, P. (Manager), Barth, D. (Participant), Penttilä, M. (Owner), Ylinen, A. (Participant), Peltonen, K. (Participant), Krogerus, K. (Participant), Koponen, T. (Participant) & Martinez Espana, L. (Participant)
1/10/22 → 30/09/26
Project: EU project
-
Inducible Synthetic Growth Regulation Using the ClpXP Proteasome Enhances cis,cis-Muconic Acid and Glycolic Acid Yields in Saccharomyces cerevisiae
Kakko, N., Rantasalo, A., Koponen, T., Vidgren, V., Kannisto, M., Maiorova, N., Nygren, H., Mojzita, D., Penttilä, M. & Jouhten, P., 21 Apr 2023, In: ACS Synthetic Biology. 12, 4, p. 1021-1033Research output: Contribution to journal › Article › Scientific › peer-review
Open Access2 Citations (Scopus) -
Biology Meets Mechatronics (BIOMEETSMEX) - Video Reporting for Development of Project Management and Interdisciplinarity Skills
Koponen, T., Lintilä, T., Vanamo, A., Taalas, A., Viskari, H., Nordström, K., Kiviluoma, P. & Ora, A., Jan 2018, p. 114-123. 10 p.Research output: Contribution to conference › Conference article › Scientific › peer-review
Equipment
-
Automation and Robotics for Biotechnology
Koponen, T. (Manager), Bennett, E. (Operator), Nyyssönen, M. (Operator) & Barth, D. (Other)
Bioanalytics and biological data scienceFacility/equipment: Facility
Activities
- 1 Other
-
Advisor of master's thesis: Jenna Arponen (Aalto university)
Koponen, T. (Participant)
2020 → …Activity: Other activity types › Other