Tuulikki Seppänen-Laakso

1988 …2019
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Research Output 1988 2019

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2019

A Small In Vitro Fermentation Model for Screening the Gut Microbiota Effects of Different Fiber Preparations

Tsitko, I., Wiik-Miettinen, F., Mattila, O., Rosa-Sibakov, N., Seppänen-Laakso, T., Maukonen, J., Nordlund, E. & Saarela, M., 18 Apr 2019, In : International Journal of Molecular Sciences. 20, 8, 1925.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
fermentation
Fermentation
Screening
screening
Microbiota
2018
2 Citations (Scopus)

Euglena gracilis growth and cell composition under different temperature, light and trophic conditions

Wang, Y., Seppänen-Laakso, T., Rischer, H. & Wiebe, M. G., 1 Apr 2018, In : PLoS ONE. 13, 4, e0195329.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Euglena gracilis
Light
Biomass
Temperature
Cells

Interlaboratory coverage test on plant food bioactive compounds and their metabolites by mass spectrometry-based untargeted metabolomics

Koistinen, V. M., da Silva, A. B., Abrankó, L., Low, D., Villalba, R. G., Barberán, F. T., Landberg, R., Savolainen, O., Alvarez-Acero, I., de Pascual-Teresa, S., Van Poucke, C., Almeida, C., Petrásková, L., Valentová, K., Durand, S., Wiczkowski, W., Szawara-Nowak, D., González-Domínguez, R., Llorach, R., Andrés-Lacueva, C. & 5 others, Aura, A. M., Seppänen-Laakso, T., Hanhineva, K., Manach, C. & Bronze, M. R., 1 Sep 2018, In : Metabolites. 8, 3, 46.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Edible Plants
Metabolomics
Metabolites
Mass spectrometry
Mass Spectrometry
2 Citations (Scopus)

In Vitro Gut Metabolism of [U-13C]-Quinic Acid, The Other Hydrolysis Product of Chlorogenic Acid

Naranjo Pinta, M., Montoliu, I., Aura, A. M., Seppänen-Laakso, T., Barron, D. & Moco, S., 1 Nov 2018, In : Molecular Nutrition and Food Research. 62, 22, 1800396.

Research output: Contribution to journalArticleScientificpeer-review

Caffeic Acids
Quinic Acid
Chlorogenic Acid
quinic acid
chlorogenic acid
3 Citations (Scopus)
Open Access
Plant Cells
Food
Vaccinium vitis-idaea
Fruit
Hydrolysis

Prepartal high-energy feeding with grass silage-based diets does not disturb the hepatic adaptation of dairy cows during the periparturient period

Qin, N., Kokkonen, T., Salin, S., Seppänen-Laakso, T., Taponen, J., Vanhatalo, A. & Elo, K., 1 Oct 2018, In : Journal of Dairy Science. 101, 10, p. 8929-8943 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Silage
grass silage
Poaceae
dairy cows
Diet
2017
1 Citation (Scopus)

Chemical profiling and bioactivity of body wall lipids from strongylocentrotus droebachiensis

Shikov, A. N., Laakso, I., Pozharitskaya, O. N., nen-Laakso, T. S., Krishtopina, A. S., Makarova, M. N., Vuorela, H. & Makarov, V., 24 Nov 2017, In : Marine Drugs. 15, 12, 365.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Strongylocentrotus
Lipids
Fatty Acids
Palmitic Acids
Monounsaturated Fatty Acids
17 Citations (Scopus)

Inheritance of brewing-relevant phenotypes in constructed Saccharomyces cerevisiae x Saccharomyces eubayanus hybrids

Krogerus, K., Seppänen-Laakso, T., Castillo, S. & Gibson, B., 21 Apr 2017, In : Microbial Cell Factories. 16, 1, 66.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Brewing
Saccharomyces
Beer
Yeast
Flavors

Liquid chromatography-mass spectrometry (LC-MS)-based analysis of molecular lipids in algae samples

Nygren, H., Seppänen-Laakso, T. & Rischer, H., 21 Nov 2017, In : Methods in Molecular Biology. p. 1-8

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)

Metabolite profiling of the carnivorous pitcher plants Darlingtonia and Sarracenia

Hotti, H., Gopalacharyulu, P., Seppänen-Laakso, T. & Rischer, H., 1 Feb 2017, In : PLoS ONE. 12, 2, 21 p., e0171078.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Sarraceniaceae
Sarracenia
Metabolites
metabolites
Biosynthesis

Polyketide-derived alkaloids and anthraquinones in Aloe plants and cell cultures

Hotti, H., Häkkinen, S., Rischer, H. & Seppänen-Laakso, T., 2017, In : Journal of Plant Biotechnology Research. 1, 1, p. 1-15 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
polyketides
Aloe
anthraquinones
plant cultural practices
alkaloids
2 Citations (Scopus)

Prepartal overfeeding alters the lipidomic profiles in the liver and the adipose tissue of transition dairy cows

Qin, N., Kokkonen, T., Salin, S., Seppänen-Laakso, T., Taponen, J., Vanhatalo, A. & Elo, K., 1 Feb 2017, In : Metabolomics. 13, 2, 21.

Research output: Contribution to journalArticleScientificpeer-review

Dairies
Liver
Adipose Tissue
Tissue
Phosphatidylethanolamines
Sterols
Nonesterified Fatty Acids
Esters
Fatty Acids
Phytol
9 Citations (Scopus)

Variability in the production of tannins and other polyphenols in cell cultures of 12 Nordic plant species

Suvanto, J., Nohynek, L., Seppänen-Laakso, T., Rischer, H., Salminen, J-P. & Puupponen-Pimiä, R., Aug 2017, In : Planta. 246, 2, p. 227-241 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Tannins
Polyphenols
tannins
polyphenols
cell culture
2016
32 Citations (Scopus)

A healthy Nordic diet alters the plasma lipidomic profile in adults with features of metabolic syndrome in a multicenter randomized dietary intervention

Lankinen, M. A., Schwab, U. S., Kolehmainen, M., Paananen, J., Nygrén, H., Seppänen-Laakso, T. E., Poutanen, K. S., Hyötyläinen, T., Risérus, U., Savolainen, M. J., Hukkanen, J. & Brader, L., 2016, In : Journal of Nutrition. 146, 4, p. 662-672

Research output: Contribution to journalArticleScientificpeer-review

Plasmalogens
Diet
Fruit
Lipids
Ceramides
3 Citations (Scopus)

Whole-genome metabolic model of Trichoderma reesei built by comparative reconstruction

Castillo, S., Barth, D., Arvas, M., Pakula, T. M., Pitkänen, E., Blomberg, P., Seppänen-Laakso, T., Nygren, H., Sivasiddarthan, D., Penttilä, M. & Oja, M., 2016, In : Biotechnology for Biofuels. 9, 252, 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2015
4 Citations (Scopus)

Analysis of Beers from an 1840s’ Shipwreck

Londesborough, J., Dresel, M., Gibson, B., Juvonen, R., Holopainen, U., Mikkelson, A., Seppänen-Laakso, T., Viljanen, K., Virtanen, H., Wilpola, A., Hofmann, T. & Wilhelmson, A., 2015, In : Journal of Agricultural and Food Chemistry. 63, 9, p. 2525-2536

Research output: Contribution to journalArticleScientificpeer-review

Beer
beers
Acids
Humulus
Bottles
4 Citations (Scopus)

Analysis of indole alkaloids from Rhazya stricta hairy roots by ultra-performance liquid chromatography-mass spectrometry

Akhgari, A., Laakso, I., Seppänen-Laakso, T., Yrjönen, T., Vuorela, H., Oksman-Caldentey, K-M. & Rischer, H., 2015, In : Molecules. 20, 12, p. 22621-22634

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Secologanin Tryptamine Alkaloids
Apocynaceae
Indole Alkaloids
alkaloids
Liquid chromatography
12 Citations (Scopus)

Bioactivity and chemical characterization of gonads of green sea urchin Strongylocentrotus droebachiensis from Barents Sea

Pozharitskaya, O. N., Shikov, A. N., Laakso, I., Seppänen-Laakso, T., Makarenko, I. E., Faustova, N. M., Makarova, M. N. & Makarov, V. G., 2015, In : Journal of Functional Foods. 17, p. 227-234

Research output: Contribution to journalArticleScientificpeer-review

Strongylocentrotus
Strongylocentrotus nudus
Barents Sea
Sea Urchins
Gonads
2 Citations (Scopus)

Bioconversion to Raspberry Ketone is Achieved by Several Non-related Plant Cell Cultures

Häkkinen, S., Seppänen-Laakso, T., Oksman-Caldentey, K-M. & Rischer, H., 24 Nov 2015, In : Frontiers in Plant Science. 6, p. 1-9 9 p., 1035.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
raspberries
biotransformation
ketones
cell culture
flavor compounds
7 Citations (Scopus)

Determination of terpenoid indole alkaloids in hairy roots of Rhazya stricta (Apocynaceae) by GC-MS

Akhgari, A., Laakso, I., Seppänen-Laakso, T., Yrjönen, T., Vuorela, H., Oksman-Caldentey, K-M. & Rischer, H., 2015, In : Phytochemical Analysis. 26, 5, p. 331-338

Research output: Contribution to journalArticleScientificpeer-review

Rhazya stricta
Secologanin Tryptamine Alkaloids
Apocynaceae
indole alkaloids
Rhazya

Effects of ellagitannin rich berries on blood lipid profiles, gut microbiota and metabolism of phenolic compounds in metabolic syndrome

Puupponen-Pimiä, R., Seppänen-Laakso, T., Maukonen, J., Nohynek, L., Tómas-Barberán, F. A., Törrönen, R., Kolehmainen, M., Kankainen, M., Espín, J. C., Aura, A-M., Poutanen, K., Leppänen, T., Moilanen, E. & Oksman-Caldentey, K-M., 2015, In : Dosis. 33, 3, p. 55-76

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Fruit
Lipids
Hydrolyzable Tannins
8-epi-prostaglandin F2alpha
Blood Pressure
1 Citation (Scopus)

Physicochemical characterization of sahti, an 'ancient' beer style indigenous to Finland

Ekberg, J., Gibson, B., Joensuu, J. J., Krogerus, K., Magalhães, F., Mikkelson, A., Seppänen-Laakso, T. & Wilpola, A., 2015, In : Journal of the Institute of Brewing. 121, 4, p. 464-473

Research output: Contribution to journalArticleScientificpeer-review

Finland
beers
brewing
alcohols
Alcohols
6 Citations (Scopus)

Polyketide synthases from poison hemlock (Conium maculatum L.)

Hotti, H., Seppänen-Laakso, T., Arvas, M., Teeri, T. H. & Rischer, H., 2015, In : FEBS Journal. 282, 21, p. 4141-4156

Research output: Contribution to journalArticleScientificpeer-review

Conium
Polyketide Synthases
Poisons
Starters
Biosynthesis
67 Citations (Scopus)

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

Van Moerkercke, A., Steensma, P., Schweizer, F., Pollier, J., Gariboldi, I., Payne, R., Vanden Bossche, R., Miettinen, K., Espoz, J., Purnama, P. C., Kellner, F., Seppänen-Laakso, T., O'Connor, S. E., Rischer, H., Memelink, J. & Goossens, A., 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 26, p. 8130-8135

Research output: Contribution to journalArticleScientificpeer-review

Open Access
basic helix-loop-helix transcription factors
indole alkaloids
Catharanthus roseus
monoterpenoids
Catharanthus
2014
8 Citations (Scopus)
Open Access
15 Citations (Scopus)

Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway

Ritala, A., Dong, L., Imseng, N., Seppänen-Laakso, T., Vasilev, N., van der Krol, S., Rischer, H., Maaheimo, H., Virkki, A., Brändli, J., Schillerberg, S., Eibl, R., Bouwmeester, H. & Oksman-Caldentey, K-M., 2014, In : Journal of Biotechnology. 176, p. 20-28 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Secologanin Tryptamine Alkaloids
Alkaloids
Tobacco
Fragrances
Glycosides
14 Citations (Scopus)

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients

Hilvo, M., Gade, S., Hyötyläinen, T., Nekljudova, V., Seppänen-Laakso, T., Sysi-Aho, M., Untch, M., Huober, J., von Minckwitz, G., Denkert, C., Oresic, M. & Loibl, S., 2014, In : International Journal of Cancer. 134, 7, p. 1725-1733 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Monounsaturated Fatty Acids
Triglycerides
Breast Neoplasms
Drug Therapy
Serum

Ultrahigh-performance liquid chromatography-mass spectrometry in Lipidomics

Nygren, H., Pöhö, P., Seppänen-Laakso, T., Lahtinen, U., Oresic, M. & Hyötyläinen, T., 2014, In : LC-GC North America. 32, 4, p. 286-293 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Liquid chromatography
Mass spectrometry
Lipids
Plasmalogens
2013
39 Citations (Scopus)

Effects of ellagitannin-rich berries on blood lipids, gut microbiota, and urolithin production in human subjects with symptoms of metabolic syndrome

Puupponen-Pimiä, R., Seppänen-Laakso, T., Kankainen, M., Maukonen, J., Törrönen, R., Kolehmainen, M., Leppänen, T., Moilanen, E., Nohynek, L., Aura, A-M., Poutanen, K., Tómas-Barberán, F. A., Espín, J. C. & Oksman-Caldentey, K-M., 2013, In : Molecular Nutrition and Food Research. 57, 12, p. 2258-2263 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Hydrolyzable Tannins
metabolic syndrome
intestinal microorganisms
blood lipids
signs and symptoms (animals and humans)
33 Citations (Scopus)

Plant cells as pharmaceutical factories

Rischer, H., Häkkinen, S., Ritala, A., Seppänen-Laakso, T., Miralpeix, B., Capell, T., Christou, P. & Oksman-Caldentey, K-M., 2013, In : Current Pharmaceutical Design. 19, 31, p. 5640-5660 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Plant Cells
Pharmaceutical Preparations
Secologanin Tryptamine Alkaloids
Tropanes
Viridiplantae

Rasvainen kala muokkaa HDL-hiukkaskokoa ja lipidipitoisuuksia

Joukamo, L., Lankinen, M., Schwab, U., Soininen, P., Kangas, A. J., Kolehmainen, M., Paananen, J., Poutanen, K., Mykkänen, H., Seppänen-Laakso, T., Gylling, H., Oresic, M., Ala-Korpela, M. & Uusitupa, M., 2013, In : Duodecim. 129, 24, p. 2661-70 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2012
29 Citations (Scopus)

Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction

Ylipaasto, P., Smura, T., Gopalacharyulu, P., Paananen, A., Seppänen-Laakso, T., Kaijalainen, S., Ahlfors, H., Korsgren, O., Lakey, J. R. T., Lahesmaa, R., Piemonti, L., Oresic, M., Galama, J. & Roivainen, M., 2012, In : Diabetologia. 55, 12, p. 3273-3283 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Enterovirus
Islets of Langerhans
Transcriptome
Enterovirus Infections
Viruses
47 Citations (Scopus)

Insulin signaling regulates fatty acid catabolism at the level of CoA activation

Xu, X., Gopalacharyulu, P., Seppänen-Laakso, T., Ruskeepää, A-L., Cho Aye, C., Carson, A., Mora, S., Orešič, M. & Teleman, A. A., 2012, In : PLoS Genetics. 8, 1, 14 p., e1002478.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
catabolism
Coenzyme A
insulin
Fatty Acids
fatty acid

Metaboliikka mahdollistaa Alzheimerin taudin toteamisen jo varhaisvaiheessa

Oresic, M., Hyötyläinen, T., Herukka, S-K., Sysi-Aho, M., Mattila, I., Seppänen-Laakso, T., Julkunen, V., Hallikainen, M., Koikkalainen, J., Kivipelto, M., Helisalmi, S., Lötjönen, J., Soininen, H., Gopalacharyulu, P. & Koikkalainen, J., 2012, In : Duodecim. 2012-3

Research output: Contribution to journalArticleProfessional

Open Access
55 Citations (Scopus)

Phospholipids and insulin resistance in psychosis: A lipidomics study of twin pairs discordant for schizophrenia

Orešič, M., Seppänen-Laakso, T., Sun, D., Tang, J., Therman, S., Viehman, R., Mustonen, U., van Erp, T. G. M., Hyötyläinen, T., Thompson, P., Toga, A. W., Huttunen, M. O., Suvisaari, J., Kaprio, J., Lönnqvist, J. & Cannon, T. D., 2012, In : Genome Medicine. 4, 11 p., 1.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Twin Studies
Psychotic Disorders
Insulin Resistance
Phospholipids
Schizophrenia
2011
67 Citations (Scopus)

Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes

Pflueger, M., Seppänen-Laakso, T., Suortti, T., Hyötyläinen, T., Achenbach, P., Bonifacio, E., Oresic, M. & Ziegler, A-G., 2011, In : Diabetes. 60, 11, p. 2740-2747 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
Lipids
Amino Acids
132 Citations (Scopus)

Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans

Pietiläinen, K. H., Róg, T., Seppänen-Laakso, T., Virtue, S., Gopalacharyulu, P., Tang, J., Rodriguez-Cuenca, S., Maciejewski, A., Naukkarinen, J., Ruskeepää, A-L., Niemelä, P., Yetukuri, L., Tan, C. Y., Velagapudi, V., Castillo, S., Nygren, H., Hyötyläinen, T., Rissanen, A., Kaprio, J., Yki-Järvinen, H. & 3 others, Vattulainen, I., Vidal-Puig, A. & Orešič, M., 2011, In : PLoS Biology. 9, 6, 14 p., e1000623.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
adipocytes
Adipocytes
adipose tissue
Adipose Tissue
obesity
68 Citations (Scopus)

Human tear fluid lipidome: From composition to function

Rantamäki, A. H., Seppänen-Laakso, T., Orešič, M., Jauhiainen, M. & Holopainen, J. M., 2011, In : PLoS ONE. 6, 5, 7 p., e19553.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Tears
Lipids
Fluids
lipids
Chemical analysis
74 Citations (Scopus)

Metabolic regulation in progression to autoimmune diabetes

Sysi-Aho, M., Erlomov, A., Gopalacharyulu, P., Tripathi, A., Seppänen-Laakso, T., Maukonen, J., Mattila, I., Ruohonen, S. T., Vähätalo, L., Yetukuri, L., Härkönen, T., Lindfors, E., Nikkilä, J., Ilonen, J., Simell, O., Saarela, M., Knip, M., Kaski, S., Savontaus, E. & Orešič, M., 2011, In : PLoS Computational Biology. 7, 10, 16 p., e1002257.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
insulin-dependent diabetes mellitus
diabetes
Diabetes
Medical problems
Type 1 Diabetes Mellitus
22 Citations (Scopus)

Metabolome in progression to Alzheimer's disease

Orešič, M., Hyötyläinen, T., Herukka, S-K., Sysi-Aho, M., Mattila, I., Seppänen-Laakso, T., Julkunen, V., Gopalacharyulu, P., Hallikainen, M., Koikkalainen, J., Kivipelto, M., Helisalmi, S., Lötjönen, J. & Soininen, H., 2011, In : Translational Psychiatry. 1, 9 p., e57.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Metabolome
Alzheimer Disease
Metabolomics
Phospholipid Ethers
Pentose Phosphate Pathway
82 Citations (Scopus)

Metabolome in schizophrenia and other psychotic disorders: A general population-based study

Oresic, M., Tang, J., Seppänen-Laakso, T., Mattila, I., Saarni, S. E., Saarni, S. I., Lönnqvist, J., Sysi-Aho, M., Hyötyläinen, T., Perälä, J. & Suvisaari, J., 2011, In : Genome Medicine. 3, 19

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Metabolome
Psychotic Disorders
Schizophrenia
Metabolomics
Proline
253 Citations (Scopus)

Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression

Hilvo, M., Denkert, C., Lehtinen, L., Muller, B., Brockmoller, S., Seppänen-Laakso, T., Budczies, J., Bucher, E., Yetukuri, L., Castillo, S., Berg, E., Nygren, H., Sysi-Aho, M., Griffin, J. L., Fiehn, O., Loibl, S., Richter-Ehrenstein, C., Radke, C., Hyötyläinen, T., Kallioniemi, O. & 2 others, Iljin, K. & Oresic, M., 2011, In : Cancer Research. 71, 9, p. 3236-3245 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Membrane Lipids
Lipid Metabolism
Breast Neoplasms
Lipids
Genes
51 Citations (Scopus)

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins

Vainio, P., Lehtinen, L., Mirtti, T., Hilvo, M., Seppänen-Laakso, T., Virtanen, J., Sankila, A., Nordling, S., Lundin, J., Rannikko, A., Orešič, M., Kallioniemi, O. & Iljin, K., 2011, In : Oncotarget. 2, 12, p. 1176-1190 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Phospholipases
Cell Movement
Prostatic Neoplasms
Biomarkers

Rasvasolujen solukalvo mukautuu ylimääräiseen rasvaan

Pietiläinen, K. H., Róg, T., Seppänen-Laakso, T., Virtue, S., Gopalacharyulu, P., Tang, J., Rodriguez-Cuenca, S., Maciejewski, A., Naukkarinen, J., Ruskeepää, A-L., Niemelä, P., Yetukuri, L., Tan, C. Y., Velagapudi, V., Castillo, S., Nygren, H., Hyötyläinen, T., Rissanen, A., Kaptio, J., Yki-Järvinen, H. & 3 others, Vattulainen, I., Vidal-Puig, A. & Oresic, M., 2011, In : Duodecim. 127, 14, 1493.

Research output: Contribution to journalArticleScientific

Open Access
21 Citations (Scopus)

Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy

Sysi-Aho, M., Koikkalainen, J., Seppänen-Laakso, T., Kaartinen, M., Kuusisto, J., Peuhkurinen, K., Kärkkäinen, S., Antila, M., Lauerma, K., Reissell, E., Jurkko, R., Lötjönen, J., Heliö, T. & Oresic, M., 2011, In : PLoS ONE. 6, 1, 9 p., e15744.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Lamin Type A
cardiomyopathy
Dilated Cardiomyopathy
Magnetic resonance
magnetic resonance imaging
57 Citations (Scopus)

Whole grain products, fish and bilberries alter glucose and lipid metabolism in a randomized, controlled trial: The Sysdimet study

Lankinen, M., Schwab, U., Kolehmainen, M., Paananen, J., Poutanen, K., Mykkänen, H., Seppänen-Laakso, T., Gylling, H., Uusitupa, M. & Orešič, M., 2011, In : PLoS ONE. 6, 8, 13 p., e22646.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Fish products
Vaccinium myrtillus
Fish Products
bilberries
grain products
2010
94 Citations (Scopus)

Comparison of lipid and fatty acid composition of the liver, subcutaneous and intra-abdominal adipose tissue, and serum

Kotronen, A., Seppänen-Laakso, T., Westerbacka, J., Kiviluoto, T., Arola, J., Ruskeepää, A-L., Yki-Järvinen, H. & Orešič, M., 2010, In : Obesity. 18, 5, p. 937-944 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Intra-Abdominal Fat
Ceramides
Fatty Acids
Lipids
Liver
77 Citations (Scopus)

Composition and lipid spatial distribution of HDL particles in subjects with low and high HDL-cholesterol

Yetukuri, L., Söderlund, S., Koivuniemi, A., Seppänen-Laakso, T., Niemelä, P., Hyvönen, M., Taskinen, M-R., Vattulainen, I., Jauhiainen, M. & Oresic, M., 2010, In : Journal of Lipid Research. 51, 8, p. 2341-2351 11 p.

Research output: Contribution to journalArticleScientificpeer-review

HDL Cholesterol
Spatial distribution
LDL Cholesterol
Lipids
Chemical analysis
41 Citations (Scopus)

Dietary carbohydrate modification alters serum metabolic profiles in individuals with the metabolic syndrome

Lankinen, M., Schwab, U., Gopalacharyulu, P., Seppänen-Laakso, T., Yetukuri, L., Sysi-Aho, M., Kallio, P., Suortti, T., Laaksonen, D. E., Gylling, H., Poutanen, K., Kolehmainen, M. & Orešič, M., 2010, In : Nutrition, Metabolism and Cardiovascular Diseases. 20, 4, p. 249-257 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Dietary Carbohydrates
Diet Therapy
Metabolome
Bread
Adipose Tissue