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2015
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma
Duffy, D. J., Krstic, A., Halász, M., Schwarzl, T., Fey, D., Iljin, K., Mehta, J. P. R., Killick, K. E., Whilde, J., Turriziani, B., Haapa-Paananen, S., Fey, V. & et al., 2015, In: Oncotarget. 6, 41, p. 43182-43201Research output: Contribution to journal › Article › Scientific › peer-review
Open Access24 Citations (Scopus) -
Integrin endosomal signalling suppresses anoikis
Alanko, J., Mai, A., Jacquemet, G., Schauer, K., Kaukonen, R., Saari, M., Goud, B. & Ivaska, J., 2015, In: Nature Cell Biology. 17, p. 1412-1421Research output: Contribution to journal › Article › Scientific › peer-review
102 Citations (Scopus) -
Investigation of photothermolysis therapy of human skin diseases using optical phantoms
Jędrzejewska-Szczerska, M., Wróbel, M. S., Galla, S., Popov, A. P., Bykov, A. V., Tuchin, V. V. & Cenian, A., 1 Jan 2015, 18th International School on Quantum Electronics: Laser Physics and Applications. Dreischuh, T., Gateva, S. & Serafetinides, A. (eds.). International Society for Optics and Photonics SPIE, 944715. (Proceedings of SPIE, Vol. 9447).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
15 Citations (Scopus) -
Large-aperture MOEMS Fabry-Perot interferometer for miniaturized spectral imagers
Rissanen, A., Langner, A., Viherkanto, K. & Mannila, R., 27 Feb 2015, MOEMS and Miniaturized Systems XIV. International Society for Optics and Photonics SPIE, 93750J. (Proceedings of SPIE, Vol. 9375).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
8 Citations (Scopus) -
Learning from disaster and experience: Evolving software professionalism
Fraser, S., Järvinen, J., Lundh, E., Power, K., Rising, L., Wild, W. & Wirfs-Brock, R., 2015, Agile Processes, in Software Engineering, and Extreme Programming: 16th International Conference, XP 2015, Proceedings. Dingsoyr, T., Lassenius, C. & Paasivaara, M. (eds.). Springer, p. 334-338 5 p. (Lecture Notes in Business Information Processing, Vol. 212).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
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Liikenteen energiatehokkuustoimenpiteet osana EU:n 2030 ilmasto- ja energiatavoitteiden saavuttamista: vaikutukset, kustannukset ja työnjako
Tuominen, A., Tervonen, J., Järvi, T., Mäkelä, K., Liimatainen, H., Nykänen, L. & Rehunen, A., 2015, 61 p. (Valtioneuvoston selvitys- ja tutkimustoiminnan julkaisusarja, Vol. 14/2015).Research output: Book/Report › Report
Open Access -
Microfluidic sampling system for tissue analytics
Hokkanen, A., Stuns, I., Schmidt, P., Kokkonen, A., Gao, F., Steinecker, A., Budczies, J., Heimala, P. & Hakalahti, L., 2015, In: Biomicrofluidics. 9, 5, 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
3 Citations (Scopus) -
MicroRNA-135b regulates ERa, AR and HIF1AN and affects breast and prostate cancer cell growth
Anna, A., Leivonen, S-K., Hintsanen, P., Aittokallio, T., Ceder, Y., Børresen-Dale, A-L., Perälä, M., Östling, P. & Kallioniemi, O., 2015, In: Molecular Oncology. 9, 7, p. 1287-1300Research output: Contribution to journal › Article › Scientific › peer-review
32 Citations (Scopus) -
MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase
Mäki-Jouppila, J. H. E., Pruikkonen, S., Tambe, M. B., Aure, M. R., Halonen, T., Salmela, A-L., Laine, L., Børresen-Dale, A-L. & Kallio, M. J., 2015, In: Molecular Oncology. 9, 6, p. 1056-1070Research output: Contribution to journal › Article › Scientific › peer-review
14 Citations (Scopus) -
Mind the gap-deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites-a position paper focusing on carotenoids and polyphenols
Bohn, T., Mcdougall, G. J., Alegría, A., Alminger, M., Arrigoni, E., Aura, A. M., Brito, C., Cilla, A., El, S. N., Karakaya, S., Martínez-Cuesta, M. C. & Santos, C. N., Jul 2015, In: Molecular Nutrition and Food Research. 59, 7, p. 1307-1323 17 p.Research output: Contribution to journal › Review Article › peer-review
Open Access120 Citations (Scopus) -
Novel test approach for evaluating barrier properties of food contact materials against mineral oil contaminants
Laine, C., Pitkänen, M., Ohra-aho, T., Gestranius, M. & Ketoja, J., 2015, Book of Abstracts: 7th International Symposium on Recent Advances in Food Analysis. Pulkrabová, J., Tomaniová, M., Nielen, M. & Hajšlová, J. (eds.). University of Chemistry and Technology, Prague, 145Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Scientific
Open Access -
One compartment fermentation model
Aura, A. M. & Maukonen, J., 1 Jan 2015, The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models. Verhoeckx, K. & E. A. (eds.). Springer, p. 281-292 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Scientific › peer-review
Open Access4 Citations (Scopus) -
Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development
Härmä, V., Haavikko, R., Virtanen, J., Ahonen, I., Schukov, H-P., Alakurtti, S., Purev, E., Rischer, H., Yli-Kauhaluoma, J., Moreira, V. M., Nees, M. & Oksman-Caldentey, K-M., 2015, In: PLoS ONE. 10, 5, 22 p., e0126111.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access14 Citations (Scopus) -
Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions
Oeder, S., Kanashova, T., Sippula, O., Sapcariu, S. C., Streibel, T., Arteaga-Salas, J. M., Passig, J., Dilger, M., Paur, H-R., Schlager, C., Mülhopt, S., Diabaté, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H., Torvela, T., Jokiniemi, J. K., Hirvonen, M-R. & al, E., 2015, In: PLoS ONE. 10, 6, e0126536.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access70 Citations (Scopus) -
Patient-specific induced pluripotent stem cell-derived RPE cells: Understanding the pathogenesis of retinopathy in long-chain 3-hydroxyacyl-CoA dehydrogenase deiciency
Polinati, P. P., Ilmarinen, T., Trokovic, R., Hyötyläinen, T., Otonkoski, T., Suomalainen, A., Skottman, H. & Tyni, T., 2015, In: Investigative Ophthalmology and Visual Science. 56, 5, p. 3371-3382Research output: Contribution to journal › Article › Scientific › peer-review
17 Citations (Scopus) -
Roux-en-Y gastric bypass surgery induces early plasma metabolomic and lipidomic alterations in humans associated with diabetes remission
Arora, T., Velagapudi, V., Pournaras, D. J., Welbourn, R., Le Roux, C. W., Oresic, M. & Bäckhed, F., 2015, In: PLoS ONE. 10, 5, e0126401.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access38 Citations (Scopus) -
Seeking a new route for trespass prevention
Silla, A. & Kallberg, V-P., 2015, In: International Railway Journal. 55, 7, p. 40-43Research output: Contribution to journal › Article › Professional
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Segmentation of image data from complex organotypic 3D models of cancer tissues with Markov random fields
Robinson, S., Guyon, L., Nevalainen, J., Toriseva, M., Åkerfelt, M. & Nees, M., 2015, In: PLoS ONE. 10, 12, e143798.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access8 Citations (Scopus) -
Semi-automatic segmentation of prostate by directional search for edge boundaries
Kortelainen, J. M., Antila, K. J., Schmitt, A., Mougenot, C., Ehnholm, G. J. & Chopra, R., 1 Jan 2015, 22nd International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision, WSCG 2014: Communication Papers Proceedings. Skala, V. (ed.). Vaclav Skala Union Agency, p. 285-292 8 p.Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
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Serum lipid and serum metabolite components in relation to anthropometric parameters in EPIC-Potsdam participants
Foerster, J., Hyötyläinen, T., Oresic, M., Nygren, H. & Boeing, H., 2015, In: Metabolism: Clinical and Experimental. 64, 10, p. 1348-1358Research output: Contribution to journal › Article › Scientific › peer-review
8 Citations (Scopus) -
Service business model canvas: A boundary object operating as a business development tool
Hakanen, T. & Murtonen, M., 2015, In: International Journal of Industrial and Systems Engineering. 9, 8, p. 2687-2692Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Systematic review and meta-analysis of human studies to support a quantitative recommendation for whole grain intake in relation to type 2 diabetes
Chanson-Rolle, A., Meynier, A., Aubin, F., Lappi, J., Poutanen, K., Vinoy, S. & Braesco, V., 2015, In: PLoS ONE. 10, 6, e0131377.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access54 Citations (Scopus) -
Talviajan nopeusrajoitusten liikenneturvallisuusvaikutukset: Vuosien 2010-2014 onnettomuuksien tarkastelu
Peltola, H., 2015, Helsinki: Liikennevirasto. 27 p. (Liikenneviraston tutkimuksia ja selvityksiä; No. 61).Research output: Book/Report › Report
Open Access -
Telemonitoring and mobile phone-based health coaching among finnish diabetic and heart disease patients: a randomized controlled trial
Karhula, T., Vuorinen, A-L., Rääpysjärvi, K., Pakanen, M., Itkonen, P., Tepponen, M., Junno, U-M., Jokinen, T., van Gils, M., Lähteenmäki, J., Kohtamäki, K. & Saranummi, N., 2015, In: Journal of Medical Internet Research. 17, 6, e153.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access56 Citations (Scopus) -
The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes
Kostic, A. D., Gevers, D., Siljander, H., Vatanen, T., Hyötyläinen, T., Hämäläinen, A-M., Peet, A., Tillmann, V., Pöhö, P., Mattila, I., Lähdesmäki, H., Franzosa, E. A., Vaarala, O., de Goffau, M., Harmsen, H., Ilonen, J., Virtanen, S. M., Clish, C. B., Oresic, M., Huttenhower, C. & 3 others, , 2015, In: Cell Host and Microbe. 17, 2, p. 260-273Research output: Contribution to journal › Article › Scientific › peer-review
491 Citations (Scopus) -
The effect of physical adhesion promotion treatments on interfacial adhesion in cellulose-epoxy
Siljander, S., Lehmonen, J., Tanaka, A., Ketoja, J., Heikkilä, P., Putkonen, M., Lahti, J., Sarlin, E. & Vuorinen, J., 2015, Proceedings of 20th International Conference on Composite Material. 10 p.Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific
Open Access -
Tools for food chain protection
Alakomi, H-L., Hakola, L., Maukonen, J., Tsitko, I., Storgårds, E. & Sipiläinen-Malm, T., 2015, p. 98-102.Research output: Contribution to conference › Conference Poster › Scientific
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User experience of mobile coaching for stress-management to tackle prevalent health complaints
Harjumaa, M., Halttu, K., Koistinen, K. & Oinas-Kukkonen, H., 2015, Nordic Contributions in IS Research: SCIS 2015. Springer, p. 152-164 (Lecture Notes in Business Information Processing, Vol. 223).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
3 Citations (Scopus) -
User experiences of a mobile mental well-being intervention among pregnant women
Muuraiskangas, S., Mattila, E., Kyttälä, P., Koreasalo, M. & Lappalainen, R., 9 Apr 2015, Pervasive Computing Paradigms for Mental Health: MindCare 2015. Springer, p. 140-149 (Communications in Computer and Information Science, Vol. 604).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
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User experiences of a mobile mental well-being intervention among pregnant women
Muuraiskangas, S., Mattila, E. M., Kyttälä, P., Koreasalo, M. & Lappalainen, R., 24 Sep 2015, Pervasive Computing Paradigms for Mental Health: MindCare 2015. Serino, S., Matic, A., Lopez, G. & Cipresso, P. (eds.). Springer, p. 140-149 (Communications in Computer and Information Science, Vol. 604).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
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Vimentin-ERK signaling uncouples Slug gene regulatory function
Virtakoivu, R., Mai, A., Mattila, E., De Franceschi, N., Imanishi, S. Y., Corthals, G., Kaukonen, R., Saari, M., Cheng, F., Torvaldson, E., Kosma, V-M., Mannermaa, A., Muharram, G., Gilles, C., Eriksson, J., Soini, Y., Lorens, J. B. & Ivaska, J., 2015, In: Cancer Research. 75, 11, p. 2349-2362Research output: Contribution to journal › Article › Scientific › peer-review
62 Citations (Scopus) -
2014
A model of suicide and trespassing processes to support the analysis and decision related to preventing railway suicides and trespassing accidents at railways
Burkhardt, J-M., Rådbo, H., Silla, A. & Paran, F., 2014, Transport Research Arena (TRA) 2014 Proceedings. 9 p.Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific
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Anaerobic carbon metabolism of saccharomyces cerevisiae
Jouhten, P. & Penttilä, M., 1 Apr 2014, Molecular Mechanisms in Yeast Carbon Metabolism. Springer, p. 57-82 26 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional
3 Citations (Scopus) -
Application of cryobiotechnologies for development of lyophilized polyenzyme complexes
Doneva, M., Nacheva, I., Metodieva, P., Todorov, Y., Miteva, D., Georgieva, L. & Tsvetkov, T., 1 Jan 2014, In: Bulgarian Journal of Agricultural Science. 20, 6, p. 1401-1405 5 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Applying IDPSA in PSA level 3 - a pilot study
Karanta, I., Tyrväinen, T. & Rossi, J., 2014, VTT Technical Research Centre of Finland. 23 p. (VTT Research Report, Vol. VTT-R-05661-14).Research output: Book/Report › Report
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Bayesian network modeling of Port State Control inspection findings and ship accident involvement
Hänninen, M. & Kujala, P., 2014, In: Expert Systems with Applications. 41, 4 Part 2, p. 1632-1646 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
54 Citations (Scopus) -
Bayesian networks for maritime traffic accident prevention: Benefits and challenges
Hänninen, M., Dec 2014, In: Accident Analysis and Prevention. 73, p. 305-312 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
97 Citations (Scopus) -
Betulin derivatives impair Leishmania braziliensis viability and host-parasite interaction
Alcazar, W., López, A. S., Alakurtti, S., Tuononen, M-L., Yli-Kauhaluoma, J. & Ponte-Sucre, A., 2014, In: Bioorganic & Medicinal Chemistry. 22, 21, p. 6220-6226Research output: Contribution to journal › Article › Scientific › peer-review
10 Citations (Scopus) -
Cancer biology, toxicology and alternative methods development go hand-in-hand
Kohonen, P., Ceder, R., Smit, I., Hongisto, V., Myatt, G., Hardy, B., Spjuth, O. & Grafström, R., 2014, In: Basic and Clinical Pharmacology and Toxicology. 115, 1, p. 50-58Research output: Contribution to journal › Article › Scientific › peer-review
20 Citations (Scopus) -
Characterising metabolically healthy obesity in weight-discordant monozygotic twins
Naukkarinen, J., Heinonen, S., Hakkarainen, A., Lundbom, J., Vuolteenaho, K., Saarinen, L., Hautaniemi, S., Rodriguez, A., Frühbeck, G., Pajunen, P., Hyötyläinen, T., Oresic, M., Moilanen, E., Suomalainen, A., Lundbom, N., Kaprio, J., Rissanen, A. & Pietiläinen, K. H., 2014, In: Diabetologia. 57, 1, p. 167-176Research output: Contribution to journal › Article › Scientific › peer-review
93 Citations (Scopus) -
Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues
Gardberg, M., Heuser, V. D., Iljin, K., Kampf, C., Uhlen, M. & Carpén, O., 2014, In: Journal of Histochemistry and Cytochemistry. 62, 6, p. 460-470Research output: Contribution to journal › Article › Scientific › peer-review
Open Access14 Citations (Scopus) -
Circulating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity
Hyysalo, J., Gopalacharyulu, P., Bian, H., Hyötyläinen, T., Leivonen, M., Jaser, N., Juuti, A., Honka, M-J., Nuutila, P., Olkkonen, V. M., Oresic, M. & Yki-Järvinen, H., 2014, In: Diabetes. 63, 1, p. 312-322Research output: Contribution to journal › Article › Scientific › peer-review
44 Citations (Scopus) -
Complex in vitro and in vivo prostate cancer models for the PREDECT consortium: Abstract
Vidic, S., Esser, N., de Hoogt, R., Verberne, I., Kogan-Sakin, I., Yan Stein, Y., Rotter, V., Barbier, M., Chong, Y., Breucker, S. D., Smans, K., Akerfelt, M., Nees, M., King, P., Hickson, I., van Weerden, W. & Graeser, R., 2014, In: Cancer Research. 74, 19 Supplement, 2023.Research output: Contribution to journal › Review Article
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Crowdsourcing novel childhood predictors of adult obesity
Bevelander, K. E., Kaipainen, K., Swain, R., Dohle, S., Bongard, J. C., Hines, P. D. H. & Wansink, B., 2014, In: PLoS ONE. 9, 2, e87756.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access24 Citations (Scopus) -
Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
Tahiri, A., Leivonen, S-K., Lüders, T., Steinfeld, I., Aure, M. R., Geisler, J., Mäkelä, R., Nord, S., Riis, M. L. H., Yakhini, Z., Sahlberg, K. K., Børressen-Dale, A-L., Perälä, M., Bukholm, I. R. K. & Kristensen, V. N., 2014, In: Carcinogenesis. 35, 1, p. 76-85Research output: Contribution to journal › Article › Scientific › peer-review
Open Access85 Citations (Scopus) -
Dipeptidyl peptidase IV as a potential target for selective prodrug activation and chemotherapeutic action in cancers
Landowski, C., Dahan, A., Wolk, O., Yang, P., Mittal, S., Wu, Z., Landowski, C. P. & Amidon, G. L., Dec 2014, In: Molecular Pharmaceutics. 11, 12, p. 4385-94Research output: Contribution to journal › Article › Scientific › peer-review
5 Citations (Scopus) -
Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1
Mai, A., Muharram, G., Barrow-McGee, R., Baghirov, H., Rantala, J., Kermorgant, S. & Ivaska, J., 2014, In: Journal of Cell Science. 127, 9, p. 1938-1952Research output: Contribution to journal › Article › Scientific › peer-review
23 Citations (Scopus) -
Evaluation of measures, recommendations and guidelines for further implementation: RESTRAIL Deliverable D5.2
Plaza, J., Bernard, V., Burkhardt, J-M., Abbott, P., Elmadagli, B., Hedvist, M., Hoogcarspel, B., Kallberg, V-P., Ladwig, K-H., Lukaschek, K., Rådbo, H., Rafaeli, G., Ryan, B., Silla, A., Whalley, S. & Van der Veer, A., 2014, 164 p.Research output: Book/Report › Report
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Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo
Winsel, S., Mäki-Jouppila, J., Tambe, M., Aure, M. R., Pruikkonen, S-M., Salmela, A., Halonen, T., Leivonen, S., Kallio, L., Børresen-Dale, A-L. & Kallio, M. J., 2014, In: British Journal of Cancer. 111, p. 2142-2151Research output: Contribution to journal › Article › Scientific › peer-review
Open Access18 Citations (Scopus) -
Foam forming-the effects of surfactant type on characteristics of fiber-foam suspension and properties of formed fiber network
Salminen, K., Lappalainen, T., Kinnunen-Raudaskoski, K., Andersson, M., Carlsson, G. & Mira, I., 2014, Tappi Proceedings: PaperCon 2014 . TAPPI Press, Vol. 1-3. p. 758-765Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review