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• 2013

  BIOSMHARS: Model description and validation: Deliverable 4.3

  Kokkonen, E., Kulmala, I. & Lehtimäki, M., 2013, BIOSMHARS project. 51 p.

  Research output: Book/Report › Report

  Open Access

  • microorganisms
  • microbial contamination
  • flight
  • aircraft
  • infectious diseases

• Break-induced replication repair of damaged forks induces genomic duplications in human cells

  Costantino, L., Sotiriou, S. K., Rantala, J. K., Magin, S., Mladenov, E., Helleday, T., Haber, J. E., Iliakis, G., Kallioniemi, O. P. & Halazonetis, T. D., 2013, In: Science. 343, 6166, p. 88-91

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Cyclin E
  • DNA Replication
  • Mammals
  • Genomic Segmental Duplications
  • DNA Polymerase III
  255 Citations (Scopus)

• Business challenges of SMEs providing ICT-solutions for wellness and healthcare domains

  Jaring, P., Pikkarainen, M. & Koivumäki, T., 2013, In: Journal of Business Market Management. 6, 1, p. 38-55 18 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Wellness
  • Information and Communication Technology
  • Elderly People
  • Small and Medium-sized Enterprises (SMEs)
  • Healthcare

• Cell-based functional screening of modified betulins, abietanes and resin acids as lead compounds for anti-cancer drugs (BARC)

  Nees, M., Haavikko, R., Moreira, V., Alakurtti, S., Yli-Kauhaluoma, J., Rischer, H., Purev, E., Virtanen, J. & Oksman-Caldentey, K-M., 2013, TERPNET 2013: Book of Abstracts. Aristotle University of Thessaloniki, p. 88 1 p. O53

  Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Scientific

  Open Access

• Ceramides in the pathophysiology of the anterior segment of the eye

  Robciuc, A., Hyötyläinen, T., Jauhiainen, M. & Holopainen, J. M., 2013, In: Current Eye Research. 38, 10, p. 1006-1016

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Anterior Eye Segment
  • Ceramides
  • Eye
  • Sphingolipids
  • Lipids
  8 Citations (Scopus)

• Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: Alterations in glutamine and beta-alanine metabolism

  Budczies, J., Brockmöller, S. F., Müller, B. M., Barupal, D. K., Richter-Ehrenstein, C., Kleine-Tebbe, A., Griffin, J. L., Orešič, M., Dietel, M., Denkert, C. & Fiehn, O., 2013, In: Journal of Proteomics. 94, p. 279-288

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Metabolomics
  • beta-Alanine
  • Metabolism
  • Glutamine
  • Estrogen Receptors
  91 Citations (Scopus)

• Comparative nontargeted profiling of metabolic changes in tissues and biofluids in high-fat diet-fed Ossabaw pig

  Hanhineva, K., Barri, T., Kolehmainen, M., Pekkinen, J., Pihlajamäki, J., Vesterbacka, A., Solano-Aguilar, G., Mykkänen, H., Dragsted, L. O., Urban, J. F. & Poutanen, K., 2013, In: Journal of Proteome Research. 12, 9, p. 3980-3992 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Metabolites
  • Nutrition
  • High Fat Diet
  • Tissue
  • Swine
  20 Citations (Scopus)

• Comparison of postprandial phenolic acid excretions and glucose responses after ingestion of breads with bioprocessed or native rye bran

  Lappi, J., Aura, A-M., Katina, K., Nordlund, E., Kolehmainen, M., Mykkänen, H. & Poutanen, K., 2013, In: Food and Function. 4, 6, p. 972-981 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • rye bran
  • Secale
  • phenolic acid
  • Bread
  • phenolic acids
  27 Citations (Scopus)

• Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes

  Orešič, M., Gopalacharyulu, P., Mykkänen, J., Lietzen, N., Mäkinen, M., Nygren, H., Simell, S., Simell, V., Hyöty, H., Veijola, R., Ilonen, J., Sysi-Aho, M., Knip, M., Hyötyläinen, T. & Simell, O., 1 Sep 2013, In: Diabetes. 62, 9, p. 3268-3274 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Autoimmunity
  • Type 1 Diabetes Mellitus
  • Autoantibodies
  • Serum
  • Phospholipids
  53 Citations (Scopus)

• Developing methodology in Restrail for the preliminary evaluation of preventative measures for railway suicide and trespass

  Ryan, B. & Kallberg, V-P., 2013, Rail Human Factors: Supporting reliability, safety and cost reduction. Dadashi, N., Scott, A., Wilson, J. R. & Mills, A. (eds.). London: CRC Press, p. 89-98

  Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional

  5 Citations (Scopus)

• Diabetic patient care using home user activity recognition

  Son, Y-S., Jo, J., Hee Park, J. & Pulkkinen, T., 2013, Proceedings: International Conference on ICT Convergence, ICTC 2013. IEEE Institute of Electrical and Electronic Engineers, p. 191-196

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • Home networks
  • Domestic appliances
  • Traffic control
  • Electronic mail
  • Interfaces (computer)
  1 Citation (Scopus)

• Do large intestinal events explain the protective effects of whole grain foods against type 2 diabetes?

  Lappi, J., Kolehmainen, M., Mykkänen, H. & Poutanen, K., 2013, In: Critical Reviews in Food Science and Nutrition. 53, 6, p. 631-640 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Whole Grains
  • noninsulin-dependent diabetes mellitus
  • whole grain foods
  • Medical problems
  • Fermentation
  18 Citations (Scopus)

• EoW criteria for waste-derived aggregates

  Hjelmar, O., van der Sloot, H. A., Comans, R. N. J. & Wahlström, M., 2013, In: Waste and Biomass Valorization. 4, 4, p. 809-819 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • European Union
  • Leaching
  • limit value
  • environmental protection regulation
  • leaching
  9 Citations (Scopus)

• Expression without boundaries: Cell-free protein synthesis in pharmaceutical research

  Casteleijn, M. G., Urtti, A. & Sarkhel, S., 2 Jan 2013, In: International Journal of Pharmaceutics. 440, 1, p. 39-47 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Pharmaceutical Research
  • Protein Engineering
  • Proteins
  • Pharmaceutical Preparations
  • Protein Stability
  38 Citations (Scopus)

• Feasibility of a Personal Health Technology-Based Psychological Intervention for Men with Stress and Mood Problems: Randomized Controlled Pilot Trial

  Lappalainen, P., Kaipainen, K., Lappalainen, R., Hoffrén, H., Myllymäki, T., Kinnunen, M-L., Mattila, E. M., Happonen, A. P., Rusko, H. & Korhonen, I., 2013, In: JMIR Research Protocols. 2, 1

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Biomedical Technology
  • Randomized Controlled Trials
  • Psychology
  • Technology
  • Acceptance and Commitment Therapy
  35 Citations (Scopus)

• Feasibility of collision and grounding data for probabilistic accident modeling

  Hänninen, M., Sladojevic, M., Tirunagari, S. & Kujala, P., 2013, Collision and grounding of ships and offshore structures: Proceedings of the 6th International Conference. Amdahl, J., Ehlers, S. & Leira, B. J. (eds.). Boca Raton: CRC Press, p. 1-8

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • Electric grounding
  • Accidents
  • Highway accidents
  5 Citations (Scopus)

• Feasibility study of the optical imaging of a breast cancer lesion labeled with upconversion nanoparticle biocomplexes

  Grebenik, E. A., Nadort, A., Generalova, A. N., Nechaev, A. V., Sreenivasan, V. K. A., Khaydukov, E. V., Semchishen, V. A., Popov, A. P., Sokolov, V. I., Akhmanov, A. S., Zubov, V. P., Klinov, D. V., Panchenko, V. Y., Deyev, S. M. & Zvyagin, A. V., 1 Jul 2013, In: Journal of Biomedical Optics. 18, 7, 076004.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • lesions
  • breast
  • Nanoparticles
  • cancer
  • Imaging techniques
  58 Citations (Scopus)

• FHOD1, a Formin Upregulated in Epithelial-Mesenchymal Transition, Participates in Cancer Cell Migration and Invasion

  Gardberg, M., Kaipio, K., Lehtinen, L., Mikkonen, P., Heuser, V. D., Talvinen, K., Iljin, K., Kampf, C., Uhlen, M., Grénman, R., Koivisto, M. & Carpén, O., 2013, In: PLoS ONE. 8, 9, 74923.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Epithelial Cells
  • cell movement
  • Epithelial-Mesenchymal Transition
  • Cells
  • neoplasm cells
  31 Citations (Scopus)

• Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

  Haapa-Paananen, S., Chen, P., Hellström, K., Kohonen, P., Hautaniemi, S., Kallioniemi, O. & Perälä, M., 2013, In: PLoS ONE. 8, 4, 10 p., e60930.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • glioma
  • glioblastoma
  • microRNA
  • Glioma
  • MicroRNAs
  39 Citations (Scopus)

• HeartCycle: Advanced sensors for telehealth applications

  Luprano, J., De Carvalho, P., Eilebrecht, B., Kortelainen, J. M., Muehlsteff, J., Sipilä, A., Sola, J., Teichmann, D. & Ulbrich, M., 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE Institute of Electrical and Electronic Engineers, p. 6984-6987

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • Telemedicine
  • Life Style
  • Hospitalization
  • Cardiovascular Diseases
  • Clinical Studies
  4 Citations (Scopus)

• High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1breast cancer cells

  Hongisto, V., Jernström, S., Fey, V., Mpindi, J-P., Kleivi Sahlberg, K., Kallioniemi, O. & Perälä, M., 2013, In: PLoS ONE. 8, 10, e77232.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Cell culture
  • Cells
  • Screening
  • neoplasm cells
  • screening
  93 Citations (Scopus)

• High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion

  Lehtinen, L., Ketola, K., Mäkelä, R., Mpindi, J-P., Viitala, M., Kallioniemi, O. & Iljin, K., 2013, In: Oncotarget. 4, 1, p. 48-63 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Vimentin
  • RNA Interference
  • Cell Movement
  • Breast Neoplasms
  • Intermediate Filament Proteins
  62 Citations (Scopus)

• Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion

  Costa, P., Scales, T. M. E., Ivaska, J. & Parsons, M., 2013, In: PLoS ONE. 8, 9, 74659.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • non-specific protein-tyrosine kinase
  • integrins
  • Focal Adhesion Protein-Tyrosine Kinases
  • Integrins
  • Membranes
  30 Citations (Scopus)

• In vitro evaluation of pulmonary deposition of airborne volcanic ash

  Lähde, A., Sæunn Gudmundsdottir, S., Joutsensaari, J., Tapper, U., Ruusunen, J., Ihalainen, M., Karhunen, T., Torvela, T., Jokiniemi, J., Järvinen, K., Gíslason, S. R., Briem, H. & Gizurarson, S., 2013, In: Atmospheric Environment. 70, p. 18-27 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • volcanic ash
  • ash
  • particle
  • evaluation
  • volcanic eruption
  14 Citations (Scopus)

• Lipidomics

  Pondia Pons, I. & Hyötyläinen, T., 2013, Foodomics: Advanced Mass Spectrometry in Modern Food Science and Nutrition. Cifuentes, A. (ed.). Wiley, p. 351-379

  Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional

  • Nutrition
  • Lipids
  • Metabolomics
  • Food safety
  • Mass spectrometry

• Lipidomics in nutrition and food research

  Hyötyläinen, T., Bondia-Pons, I. & Orešič, M., 2013, In: Molecular Nutrition and Food Research. 57, 8, p. 1306-1318

  Research output: Contribution to journal › Review Article › peer-review

  • nutrition research
  • food research
  • Food
  • Lipids
  • lipids
  42 Citations (Scopus)

• Low intrusive ehealth monitoring: Human posture and activity level detection with an intelligent furniture network

  Heikkilä, T., Strömmer, E., Kivikunnas, S., Järviluoma, M., Korkalainen, M., Kyllönen, V., Sarjanoja, E-M. & Peltomaa, I., 2013, In: IEEE Wireless Communications. 20, 4, p. 57-63 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • eHealth
  • Proximity sensors
  • Capacitive sensors
  • IIR filters
  • Monitoring
  10 Citations (Scopus)

• Mitosis as an anti-cancer drug target

  Salmela, A-L. & Kallio, M., 2013, In: Chromosoma. 122, 5, p. 431-449

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Mitosis
  • Aurora Kinases
  • polo-like kinase 1
  • Pharmaceutical Preparations
  • Neoplasms
  42 Citations (Scopus)

• Mobile mental wellness training for stress management: Feasibility and design implications based on a one-month field study

  Ahtinen, A., Mattila, E. M., Välkkynen, P., Kaipainen, K., Vanhala, T., Ermes, M., Sairanen, E., Myllymäki, T. & Lappalainen, R., 2013, In: JMIR Mhealth and Uhealth. 1, 2, e11.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Mobile Applications
  • Acceptance and Commitment Therapy
  • Psychology
  • Problem-Based Learning
  • Occupational Stress
  74 Citations (Scopus)

• Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone

  Ylilauri, M., Mattila, E., Nurminen, E. M., Käpylä, J., Niinivehmas, S. P., Määttä, J. A., Pentikäinen, U., Ivaska, J. & Pentikäinen, O. T., 2013, In: Biochimica et Biophysica Acta: Proteins and Proteomics. 1834, 10, p. 1988-1997

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Non-Receptor Type 2 Protein Tyrosine Phosphatase
  • Mitoxantrone
  • Chemical activation
  • Molecules
  • Spermidine
  10 Citations (Scopus)

• Nanosize mineral fillers to replace Sb2O3 synergist in PVC flame retardant system

  Härkki, O., Saarimäki, E. & Kiviranta, K., 2013, Conference proceedings: 5th international seminar Modern polymeric materials for environmental applications. Cracow, Poland: Cracow University of Technology, p. 167-174

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • flame retardant
  • hydrotalcite
  • antimony
  • nanocomposite
  • mineral

• New Technologies for Cosmetics Applications

  Nees, M., Rischer, H. & Oksman-Caldentey, K-M., 2013.

  Research output: Contribution to conference › Conference Poster › Professional

  • cosmetics
  • stem cells
  • biotechnology
  • cell culture
  • screening

• Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases

  Salmela, A-L., Pouwels, J., Mäki-Jouppila, J., Kohonen, P., Toivonen, P., Kallio, L. & Kallio, M., 2013, In: Carcinogenesis. 34, 2, p. 436-445

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Aurora Kinases
  • Diamines
  • M Phase Cell Cycle Checkpoints
  • pyrimidine
  • Cell Survival
  5 Citations (Scopus)

• Opposing effects of heat shock factors 1 and 2 on prostate cancer invasion

  Åkerfelt, M., Björk, J., Mirtti, T., Fey, V., Sistonen, L. & Nees, M., 2013, In: Cancer Research. 73, 3, A46.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Heat-Shock Response
  • Prostatic Neoplasms
  • Neoplasms
  • Castration
  • Podosomes

• Personal health technologies in employee health promotion: Usage activity, usefulness, and health-related outcomes in a 1-year randomized controlled trial

  Mattila, E. M., Orsama, A-L., Ahtinen, A., Hopsu, L., Leino, T. & Korhonen, 2013, In: JMIR Mhealth and Uhealth. 1, 2, e16.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Biomedical Technology
  • Occupational Health
  • Health Promotion
  • Randomized Controlled Trials
  • Technology
  44 Citations (Scopus)

• Plant cells as pharmaceutical factories

  Rischer, H., Häkkinen, S., Ritala, A., Seppänen-Laakso, T., Miralpeix, B., Capell, T., Christou, P. & Oksman-Caldentey, K-M., 2013, In: Current Pharmaceutical Design. 19, 31, p. 5640-5660 20 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Plant Cells
  • Pharmaceutical Preparations
  • Secologanin Tryptamine Alkaloids
  • Viridiplantae
  • Tropanes
  38 Citations (Scopus)

• Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids

  Orešič, M., Hyötyläinen, T., Kotronen, A., Gopalacharyulu, P., Nygren, H., Arola, J., Castillo, S., Mattila, I., Hakkarainen, A., Borra, R. J. H., Honka, M. J., Verrijken, A., Francque, S., Iozzo, P., Leivonen, M., Jaser, N., Juuti, A., Sørensen, T. I. A., Nuutila, P., Van Gaal, L. & 1 others, Yki-Järvinen, H., 1 Oct 2013, In: Diabetologia. 56, 10, p. 2266-2274 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Non-alcoholic Fatty Liver Disease
  • Fats
  • Lipids
  • Liver
  • Serum
  67 Citations (Scopus)

• Progressive monitoring and treatment planning of diabetes mellitus in smart home environment

  Pulkkinen, T., Son, Y-S., Lee, J., Lee, Y-H., Sallinen, M. & Park, J-H., 2013, Proceedings: IEEE International Conference on Consumer Electronics ICCE 2013. IEEE Institute of Electrical and Electronic Engineers, p. 206-207

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • Medical problems
  • Planning
  • Monitoring
  6 Citations (Scopus)

• Remote Patient Reporting and Automated Mobile Telephone Feedback Reduce HbA1c and Weight in Individuals with Type 2 Diabetes: Results of a Pilot Study

  Fisher, W., Orsama, A-L., Lähteenmäki, J., Harno, K., Kulju, M., Wintergerst, E., Schachner, H., Stenger, P., Leppänen, J., Kaijanranta, H., Salaspuro, V. & Liukko, K., 2013, In: Diabetes Technology and Therapeutics. 15, S1, p. A-8 O-21.

  Research output: Contribution to journal › Other journal contribution › Scientific

  • Cell Phone
  • Self-Management
  • Type 2 Diabetes Mellitus
  • Weights and Measures
  • Health Promotion

• Resonant biaxial 7-mm MEMS mirror for omnidirectional scanning

  Hofmann, U., Aikio, M., Janes, J., Senger, F., Stenchly, V., Wiess, M., Quenzer, H-J., Wagner, B. & Benecke, W., 2013, MOEMS and Miniaturized Systems XII. Piyawattanametha, W. & Park, Y-H. (eds.). International Society for Optics and Photonics SPIE, 86160C. (Proceedings of SPIE, Vol. 8616).

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • Mirrors
  • MEMS
  • Scanning
  • Lasers
  • Wafer bonding
  1 Citation (Scopus)

• State-of-the-art of wearable EEG for personalised health applications

  Balanou, E., van Gils, M. & Vanhala, T., 2013, Proceedings of the 10th International Conference on Wearable Micro and Nano Technologies for Personalized Health: pHealth 2013. Blobel, B., Pharow, P. & Parv, L. (eds.). Amsterdam: IOS Press, p. 119-123 (Studies in Health Technology and Informatics, Vol. 189).

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

  • Health
  • Wearable sensors
  • Brain
  • Costs
  9 Citations (Scopus)

• Swollenin aids in the amorphogenesis step during the enzymatic hydrolysis of pretreated biomass

  Gourlay, K., Hu, J., Arantes, V., Andberg, M., Saloheimo, M., Penttilä, M. & Saddler, J., 1 Jan 2013, In: Bioresource Technology. 142, p. 498-503

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Enzymatic hydrolysis
  • Cellulose
  • cellulose
  • hydrolysis
  • Biomass
  64 Citations (Scopus)

• Synthesis of betulin derivatives against intracellular pathogens: Dissertation

  Alakurtti, S., 2013, Espoo: VTT Technical Research Centre of Finland. 124 p.

  Research output: Thesis › Dissertation › Collection of Articles

  Open Access

  • betulin
  • Pathogens
  • Derivatives
  • Viruses
  • Macrophages

• The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells

  Kleivi Sahlberg, K., Hongisto, V., Edgren, H., Mäkelä, R., Hellström, K., Due, E. U., Moen Vollan, H. K., Sahlberg, N., Wolf, M., Børresen-Dale, A-L., Perälä, M. & Kallioniemi, O., 2013, In: Molecular Oncology. 7, 3, p. 392-401

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Breast Neoplasms
  • Survival
  • Growth
  • Genes
  • Trastuzumab
  54 Citations (Scopus)

• Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics

  Corchero, J. L., Gasser, B., Resina, D., Smith, W., Parrilli, E., Vázquez, F., Abasolo, I., Giuliani, M., Jäntti, J., Ferrer, P., Saloheimo, M., Mattanovich, D., Schwartz Jr, S., Tutino, M. L. & Villaverde, A., 2013, In: Biotechnology Advances. 31, 2, p. 140-153 14 p.

  Research output: Contribution to journal › Review Article › peer-review

  • Proteins
  • Biological Availability
  • Pharmacokinetics
  • Costs and Cost Analysis
  • Biocompatibility
  82 Citations (Scopus)
• 2012

  15-hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition and promotes cell migration in cultured breast cancer cells

  Lehtinen, L., Vainio, P., Wikman, H., Reemts, J., Hilvo, M., Issa, R., Pollari, S., Brandt, B., Oresic, M., Pantel, K., Kallioniemi, O. & Iljin, K., 2012, In: Journal of Pathology. 226, 4, p. 674-686 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • 15-hydroxyprostaglandin dehydrogenase
  • Epithelial-Mesenchymal Transition
  • Cell Movement
  • Breast Neoplasms
  • Arachidonic Acid
  21 Citations (Scopus)

• Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model

  Martinez-Garcia, C., Izquierdo, A., Velagapudi, V., Vivas, Y., Velasco, I., Campbell, M., Burling, K., Cava, F., Ros, M., Orešič, M., Vidal-Puig, A. & Medina-Gomez, G., 2012, In: Disease models & mechanisms. 5, 5, p. 636-648

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  • Metabolic Syndrome
  • Blood pressure
  • Lipid Metabolism
  • Kidney
  • Insulin
  28 Citations (Scopus)

• A functional genetic screen reveals new regulators of β1-integrin activity

  Pellinen, T., Rantala, J. K., Arjonen, A., Mpindi, J-P., Kallioniemi, O. & Ivaska, J., 2012, In: Journal of Cell Science. 125, 3, p. 649-661

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Integrins
  • adhesion receptor
  • Neoplasms
  • Cell Line
  • Regulator Genes
  30 Citations (Scopus)

• A monitoring and feedback service as a way to reduce the greenhouse gas emissions of consumption

  Hyvönen, K., Saastamoinen, M., Hongisto, M., Kallio, A. & Södergård, C., Mar 2012, In: International Journal of Consumer Studies. 36, 2, p. 221-227

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Greenhouse Gases
  • Greenhouse Gas Emissions
  • Monitoring
  • Climate
  • Acceptability
  2 Citations (Scopus)

• An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer

  Mamo, A., Cavallone, L., Tuzmen, S., Chabot, C., Ferrario, C., Hassan, S., Edgren, H., Kallioniemi, O., Aleynikova, O., Przybytkowski, E., Malcolm, K., Mousses, S., Tonin, P. N. & Basik, M., 2012, In: Oncogene. 31, 16, p. 2090-2100

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Breast Neoplasms
  • Nonsense Codon
  • RNA Stability
  • Cell Line
  • Phenotype
  91 Citations (Scopus)