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2013
BIOSMHARS: Model description and validation: Deliverable 4.3
Kokkonen, E., Kulmala, I. & Lehtimäki, M., 2013, BIOSMHARS project. 51 p.Research output: Book/Report › Report
Open Access -
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Costantino, L., Sotiriou, S. K., Rantala, J. K., Magin, S., Mladenov, E., Helleday, T., Haber, J. E., Iliakis, G., Kallioniemi, O. P. & Halazonetis, T. D., 2013, In: Science. 343, 6166, p. 88-91Research output: Contribution to journal › Article › Scientific › peer-review
255 Citations (Scopus) -
Business challenges of SMEs providing ICT-solutions for wellness and healthcare domains
Jaring, P., Pikkarainen, M. & Koivumäki, T., 2013, In: Journal of Business Market Management. 6, 1, p. 38-55 18 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Cell-based functional screening of modified betulins, abietanes and resin acids as lead compounds for anti-cancer drugs (BARC)
Nees, M., Haavikko, R., Moreira, V., Alakurtti, S., Yli-Kauhaluoma, J., Rischer, H., Purev, E., Virtanen, J. & Oksman-Caldentey, K-M., 2013, TERPNET 2013: Book of Abstracts. Aristotle University of Thessaloniki, p. 88 1 p. O53Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Scientific
Open Access -
Ceramides in the pathophysiology of the anterior segment of the eye
Robciuc, A., Hyötyläinen, T., Jauhiainen, M. & Holopainen, J. M., 2013, In: Current Eye Research. 38, 10, p. 1006-1016Research output: Contribution to journal › Article › Scientific › peer-review
8 Citations (Scopus) -
Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: Alterations in glutamine and beta-alanine metabolism
Budczies, J., Brockmöller, S. F., Müller, B. M., Barupal, D. K., Richter-Ehrenstein, C., Kleine-Tebbe, A., Griffin, J. L., Orešič, M., Dietel, M., Denkert, C. & Fiehn, O., 2013, In: Journal of Proteomics. 94, p. 279-288Research output: Contribution to journal › Article › Scientific › peer-review
91 Citations (Scopus) -
Comparative nontargeted profiling of metabolic changes in tissues and biofluids in high-fat diet-fed Ossabaw pig
Hanhineva, K., Barri, T., Kolehmainen, M., Pekkinen, J., Pihlajamäki, J., Vesterbacka, A., Solano-Aguilar, G., Mykkänen, H., Dragsted, L. O., Urban, J. F. & Poutanen, K., 2013, In: Journal of Proteome Research. 12, 9, p. 3980-3992 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
20 Citations (Scopus) -
Comparison of postprandial phenolic acid excretions and glucose responses after ingestion of breads with bioprocessed or native rye bran
Lappi, J., Aura, A-M., Katina, K., Nordlund, E., Kolehmainen, M., Mykkänen, H. & Poutanen, K., 2013, In: Food and Function. 4, 6, p. 972-981 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
27 Citations (Scopus) -
Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes
Orešič, M., Gopalacharyulu, P., Mykkänen, J., Lietzen, N., Mäkinen, M., Nygren, H., Simell, S., Simell, V., Hyöty, H., Veijola, R., Ilonen, J., Sysi-Aho, M., Knip, M., Hyötyläinen, T. & Simell, O., 1 Sep 2013, In: Diabetes. 62, 9, p. 3268-3274 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access53 Citations (Scopus) -
Developing methodology in Restrail for the preliminary evaluation of preventative measures for railway suicide and trespass
Ryan, B. & Kallberg, V-P., 2013, Rail Human Factors: Supporting reliability, safety and cost reduction. Dadashi, N., Scott, A., Wilson, J. R. & Mills, A. (eds.). London: CRC Press, p. 89-98Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional
5 Citations (Scopus) -
Diabetic patient care using home user activity recognition
Son, Y-S., Jo, J., Hee Park, J. & Pulkkinen, T., 2013, Proceedings: International Conference on ICT Convergence, ICTC 2013. IEEE Institute of Electrical and Electronic Engineers, p. 191-196Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
1 Citation (Scopus) -
Do large intestinal events explain the protective effects of whole grain foods against type 2 diabetes?
Lappi, J., Kolehmainen, M., Mykkänen, H. & Poutanen, K., 2013, In: Critical Reviews in Food Science and Nutrition. 53, 6, p. 631-640 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
18 Citations (Scopus) -
EoW criteria for waste-derived aggregates
Hjelmar, O., van der Sloot, H. A., Comans, R. N. J. & Wahlström, M., 2013, In: Waste and Biomass Valorization. 4, 4, p. 809-819 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access9 Citations (Scopus) -
Expression without boundaries: Cell-free protein synthesis in pharmaceutical research
Casteleijn, M. G., Urtti, A. & Sarkhel, S., 2 Jan 2013, In: International Journal of Pharmaceutics. 440, 1, p. 39-47 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
38 Citations (Scopus) -
Feasibility of a Personal Health Technology-Based Psychological Intervention for Men with Stress and Mood Problems: Randomized Controlled Pilot Trial
Lappalainen, P., Kaipainen, K., Lappalainen, R., Hoffrén, H., Myllymäki, T., Kinnunen, M-L., Mattila, E. M., Happonen, A. P., Rusko, H. & Korhonen, I., 2013, In: JMIR Research Protocols. 2, 1Research output: Contribution to journal › Article › Scientific › peer-review
Open Access35 Citations (Scopus) -
Feasibility of collision and grounding data for probabilistic accident modeling
Hänninen, M., Sladojevic, M., Tirunagari, S. & Kujala, P., 2013, Collision and grounding of ships and offshore structures: Proceedings of the 6th International Conference. Amdahl, J., Ehlers, S. & Leira, B. J. (eds.). Boca Raton: CRC Press, p. 1-8Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
5 Citations (Scopus) -
Feasibility study of the optical imaging of a breast cancer lesion labeled with upconversion nanoparticle biocomplexes
Grebenik, E. A., Nadort, A., Generalova, A. N., Nechaev, A. V., Sreenivasan, V. K. A., Khaydukov, E. V., Semchishen, V. A., Popov, A. P., Sokolov, V. I., Akhmanov, A. S., Zubov, V. P., Klinov, D. V., Panchenko, V. Y., Deyev, S. M. & Zvyagin, A. V., 1 Jul 2013, In: Journal of Biomedical Optics. 18, 7, 076004.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access58 Citations (Scopus) -
FHOD1, a Formin Upregulated in Epithelial-Mesenchymal Transition, Participates in Cancer Cell Migration and Invasion
Gardberg, M., Kaipio, K., Lehtinen, L., Mikkonen, P., Heuser, V. D., Talvinen, K., Iljin, K., Kampf, C., Uhlen, M., Grénman, R., Koivisto, M. & Carpén, O., 2013, In: PLoS ONE. 8, 9, 74923.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access31 Citations (Scopus) -
Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation
Haapa-Paananen, S., Chen, P., Hellström, K., Kohonen, P., Hautaniemi, S., Kallioniemi, O. & Perälä, M., 2013, In: PLoS ONE. 8, 4, 10 p., e60930.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access39 Citations (Scopus) -
HeartCycle: Advanced sensors for telehealth applications
Luprano, J., De Carvalho, P., Eilebrecht, B., Kortelainen, J. M., Muehlsteff, J., Sipilä, A., Sola, J., Teichmann, D. & Ulbrich, M., 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE Institute of Electrical and Electronic Engineers, p. 6984-6987Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
4 Citations (Scopus) -
High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1breast cancer cells
Hongisto, V., Jernström, S., Fey, V., Mpindi, J-P., Kleivi Sahlberg, K., Kallioniemi, O. & Perälä, M., 2013, In: PLoS ONE. 8, 10, e77232.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access93 Citations (Scopus) -
High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion
Lehtinen, L., Ketola, K., Mäkelä, R., Mpindi, J-P., Viitala, M., Kallioniemi, O. & Iljin, K., 2013, In: Oncotarget. 4, 1, p. 48-63 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access62 Citations (Scopus) -
Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion
Costa, P., Scales, T. M. E., Ivaska, J. & Parsons, M., 2013, In: PLoS ONE. 8, 9, 74659.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access30 Citations (Scopus) -
In vitro evaluation of pulmonary deposition of airborne volcanic ash
Lähde, A., Sæunn Gudmundsdottir, S., Joutsensaari, J., Tapper, U., Ruusunen, J., Ihalainen, M., Karhunen, T., Torvela, T., Jokiniemi, J., Järvinen, K., Gíslason, S. R., Briem, H. & Gizurarson, S., 2013, In: Atmospheric Environment. 70, p. 18-27 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
14 Citations (Scopus) -
Lipidomics
Pondia Pons, I. & Hyötyläinen, T., 2013, Foodomics: Advanced Mass Spectrometry in Modern Food Science and Nutrition. Cifuentes, A. (ed.). Wiley, p. 351-379Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional
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Lipidomics in nutrition and food research
Hyötyläinen, T., Bondia-Pons, I. & Orešič, M., 2013, In: Molecular Nutrition and Food Research. 57, 8, p. 1306-1318Research output: Contribution to journal › Review Article › peer-review
42 Citations (Scopus) -
Low intrusive ehealth monitoring: Human posture and activity level detection with an intelligent furniture network
Heikkilä, T., Strömmer, E., Kivikunnas, S., Järviluoma, M., Korkalainen, M., Kyllönen, V., Sarjanoja, E-M. & Peltomaa, I., 2013, In: IEEE Wireless Communications. 20, 4, p. 57-63 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
10 Citations (Scopus) -
Mitosis as an anti-cancer drug target
Salmela, A-L. & Kallio, M., 2013, In: Chromosoma. 122, 5, p. 431-449Research output: Contribution to journal › Article › Scientific › peer-review
42 Citations (Scopus) -
Mobile mental wellness training for stress management: Feasibility and design implications based on a one-month field study
Ahtinen, A., Mattila, E. M., Välkkynen, P., Kaipainen, K., Vanhala, T., Ermes, M., Sairanen, E., Myllymäki, T. & Lappalainen, R., 2013, In: JMIR Mhealth and Uhealth. 1, 2, e11.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access74 Citations (Scopus) -
Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone
Ylilauri, M., Mattila, E., Nurminen, E. M., Käpylä, J., Niinivehmas, S. P., Määttä, J. A., Pentikäinen, U., Ivaska, J. & Pentikäinen, O. T., 2013, In: Biochimica et Biophysica Acta: Proteins and Proteomics. 1834, 10, p. 1988-1997Research output: Contribution to journal › Article › Scientific › peer-review
10 Citations (Scopus) -
Nanosize mineral fillers to replace Sb2O3 synergist in PVC flame retardant system
Härkki, O., Saarimäki, E. & Kiviranta, K., 2013, Conference proceedings: 5th international seminar Modern polymeric materials for environmental applications. Cracow, Poland: Cracow University of Technology, p. 167-174Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
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New Technologies for Cosmetics Applications
Nees, M., Rischer, H. & Oksman-Caldentey, K-M., 2013.Research output: Contribution to conference › Conference Poster › Professional
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Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases
Salmela, A-L., Pouwels, J., Mäki-Jouppila, J., Kohonen, P., Toivonen, P., Kallio, L. & Kallio, M., 2013, In: Carcinogenesis. 34, 2, p. 436-445Research output: Contribution to journal › Article › Scientific › peer-review
Open Access5 Citations (Scopus) -
Opposing effects of heat shock factors 1 and 2 on prostate cancer invasion
Åkerfelt, M., Björk, J., Mirtti, T., Fey, V., Sistonen, L. & Nees, M., 2013, In: Cancer Research. 73, 3, A46.Research output: Contribution to journal › Article › Scientific › peer-review
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Personal health technologies in employee health promotion: Usage activity, usefulness, and health-related outcomes in a 1-year randomized controlled trial
Mattila, E. M., Orsama, A-L., Ahtinen, A., Hopsu, L., Leino, T. & Korhonen, 2013, In: JMIR Mhealth and Uhealth. 1, 2, e16.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access44 Citations (Scopus) -
Plant cells as pharmaceutical factories
Rischer, H., Häkkinen, S., Ritala, A., Seppänen-Laakso, T., Miralpeix, B., Capell, T., Christou, P. & Oksman-Caldentey, K-M., 2013, In: Current Pharmaceutical Design. 19, 31, p. 5640-5660 20 p.Research output: Contribution to journal › Article › Scientific › peer-review
38 Citations (Scopus) -
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids
Orešič, M., Hyötyläinen, T., Kotronen, A., Gopalacharyulu, P., Nygren, H., Arola, J., Castillo, S., Mattila, I., Hakkarainen, A., Borra, R. J. H., Honka, M. J., Verrijken, A., Francque, S., Iozzo, P., Leivonen, M., Jaser, N., Juuti, A., Sørensen, T. I. A., Nuutila, P., Van Gaal, L. & 1 others, , 1 Oct 2013, In: Diabetologia. 56, 10, p. 2266-2274 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access67 Citations (Scopus) -
Progressive monitoring and treatment planning of diabetes mellitus in smart home environment
Pulkkinen, T., Son, Y-S., Lee, J., Lee, Y-H., Sallinen, M. & Park, J-H., 2013, Proceedings: IEEE International Conference on Consumer Electronics ICCE 2013. IEEE Institute of Electrical and Electronic Engineers, p. 206-207Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
6 Citations (Scopus) -
Remote Patient Reporting and Automated Mobile Telephone Feedback Reduce HbA1c and Weight in Individuals with Type 2 Diabetes: Results of a Pilot Study
Fisher, W., Orsama, A-L., Lähteenmäki, J., Harno, K., Kulju, M., Wintergerst, E., Schachner, H., Stenger, P., Leppänen, J., Kaijanranta, H., Salaspuro, V. & Liukko, K., 2013, In: Diabetes Technology and Therapeutics. 15, S1, p. A-8 O-21.Research output: Contribution to journal › Other journal contribution › Scientific
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Resonant biaxial 7-mm MEMS mirror for omnidirectional scanning
Hofmann, U., Aikio, M., Janes, J., Senger, F., Stenchly, V., Wiess, M., Quenzer, H-J., Wagner, B. & Benecke, W., 2013, MOEMS and Miniaturized Systems XII. Piyawattanametha, W. & Park, Y-H. (eds.). International Society for Optics and Photonics SPIE, 86160C. (Proceedings of SPIE, Vol. 8616).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
1 Citation (Scopus) -
State-of-the-art of wearable EEG for personalised health applications
Balanou, E., van Gils, M. & Vanhala, T., 2013, Proceedings of the 10th International Conference on Wearable Micro and Nano Technologies for Personalized Health: pHealth 2013. Blobel, B., Pharow, P. & Parv, L. (eds.). Amsterdam: IOS Press, p. 119-123 (Studies in Health Technology and Informatics, Vol. 189).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
9 Citations (Scopus) -
Swollenin aids in the amorphogenesis step during the enzymatic hydrolysis of pretreated biomass
Gourlay, K., Hu, J., Arantes, V., Andberg, M., Saloheimo, M., Penttilä, M. & Saddler, J., 1 Jan 2013, In: Bioresource Technology. 142, p. 498-503Research output: Contribution to journal › Article › Scientific › peer-review
Open Access64 Citations (Scopus) -
Synthesis of betulin derivatives against intracellular pathogens: Dissertation
Alakurtti, S., 2013, Espoo: VTT Technical Research Centre of Finland. 124 p.Research output: Thesis › Dissertation › Collection of Articles
Open Access -
The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells
Kleivi Sahlberg, K., Hongisto, V., Edgren, H., Mäkelä, R., Hellström, K., Due, E. U., Moen Vollan, H. K., Sahlberg, N., Wolf, M., Børresen-Dale, A-L., Perälä, M. & Kallioniemi, O., 2013, In: Molecular Oncology. 7, 3, p. 392-401Research output: Contribution to journal › Article › Scientific › peer-review
Open Access54 Citations (Scopus) -
Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics
Corchero, J. L., Gasser, B., Resina, D., Smith, W., Parrilli, E., Vázquez, F., Abasolo, I., Giuliani, M., Jäntti, J., Ferrer, P., Saloheimo, M., Mattanovich, D., Schwartz Jr, S., Tutino, M. L. & Villaverde, A., 2013, In: Biotechnology Advances. 31, 2, p. 140-153 14 p.Research output: Contribution to journal › Review Article › peer-review
82 Citations (Scopus) -
2012
15-hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition and promotes cell migration in cultured breast cancer cells
Lehtinen, L., Vainio, P., Wikman, H., Reemts, J., Hilvo, M., Issa, R., Pollari, S., Brandt, B., Oresic, M., Pantel, K., Kallioniemi, O. & Iljin, K., 2012, In: Journal of Pathology. 226, 4, p. 674-686 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
21 Citations (Scopus) -
Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model
Martinez-Garcia, C., Izquierdo, A., Velagapudi, V., Vivas, Y., Velasco, I., Campbell, M., Burling, K., Cava, F., Ros, M., Orešič, M., Vidal-Puig, A. & Medina-Gomez, G., 2012, In: Disease models & mechanisms. 5, 5, p. 636-648Research output: Contribution to journal › Article › Scientific › peer-review
Open Access28 Citations (Scopus) -
A functional genetic screen reveals new regulators of β1-integrin activity
Pellinen, T., Rantala, J. K., Arjonen, A., Mpindi, J-P., Kallioniemi, O. & Ivaska, J., 2012, In: Journal of Cell Science. 125, 3, p. 649-661Research output: Contribution to journal › Article › Scientific › peer-review
30 Citations (Scopus) -
A monitoring and feedback service as a way to reduce the greenhouse gas emissions of consumption
Hyvönen, K., Saastamoinen, M., Hongisto, M., Kallio, A. & Södergård, C., Mar 2012, In: International Journal of Consumer Studies. 36, 2, p. 221-227Research output: Contribution to journal › Article › Scientific › peer-review
2 Citations (Scopus) -
An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
Mamo, A., Cavallone, L., Tuzmen, S., Chabot, C., Ferrario, C., Hassan, S., Edgren, H., Kallioniemi, O., Aleynikova, O., Przybytkowski, E., Malcolm, K., Mousses, S., Tonin, P. N. & Basik, M., 2012, In: Oncogene. 31, 16, p. 2090-2100Research output: Contribution to journal › Article › Scientific › peer-review
91 Citations (Scopus)