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2012
Application of the predictad software tool to predict progression in patients with mild cognitive impairment
Simonsen, A. H., Mattila, J., Hejl, A. M., Frederiksen, K. S., Herukka, S. K., Hallikainen, M., van Gils, M., Lötjönen, J., Soininen, H. & Waldemar, G., 2012, In: Dementia and Geriatric Cognitive Disorders. 34, 5-6, p. 344-350Research output: Contribution to journal › Article › Scientific › peer-review
Open Access11 Citations (Scopus) -
Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome
Kolehmainen, M., Mykkänen, O., Kirjavainen, P. V., Leppänen, T., Moilanen, E., Adriaens, M., Laaksonen, D. E., Hallikainen, M., Puupponen-Pimiä, R., Pulkkinen, L., Mykkänen, H., Gylling, H., Poutanen, K. & Törrönen, R., 2012, In: Molecular Nutrition and Food Research. 56, 10, p. 1501-1510 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
99 Citations (Scopus) -
Biofabrication of cancer microenvironment mimics by inkjet printing
Ilmonen, A. & Teerinen, T., 2012, Technical Program and Proceedings : 28th International Conference on Digital Printing Technologies, NIP28 & Digital Fabrication 2012, 9-13 September 2012, Quebec City, Quebec, Canada. The Society for Imaging Science and Technology, IS&T, p. 269-272Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific
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Boron neutron capture therapy in the treatment of locally recurred head-and-neck cancer: Final analysis of a phase I/II trial
Kankaanranta, L., Seppälä, T., Koivunoro, H., Saarilahti, K., Atula, T., Collan, J., Salli, E., Kortesniemi, M., Uusi-Simola, J., Välimäki, P., Mäkitie, A., Seppänen, M., Minn, H., Revitzer, H., Kouri, M., Kotiluoto, P., Seren, T., Auterinen, I., Savolainen, S. & Joensuu, H., 1 Jan 2012, In: International Journal of Radiation Oncology Biology Physics. 82, 1, p. e67-e75 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
119 Citations (Scopus) -
Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy
Finckenberg, P., Eriksson, O., Baumann, M., Merasto, S., Lalowski, M. M., Levijoki, J., Haasio, K., Kytö, V., Muller, D. N., Luft, F. C., Orešič, M. & Mervaala, E., 2012, In: Hypertension. 59, 1, p. 76-84Research output: Contribution to journal › Article › Scientific › peer-review
Open Access42 Citations (Scopus) -
CD44 expression in oro-pharyngeal carcinoma tissues and cell lines
Rajarajan, A., Stokes, A., Bloor, B. K., Ceder, R., Desai, H., Grafström, R. & Odell, E. W., 2012, In: PLoS ONE. 7, 1, 11 p., e28776.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access23 Citations (Scopus) -
Characterization of the human predominant fecal microbiota: With special focus on the Clostridial clusters IV and XIVa: Dissertation
Maukonen, J., 2012, Espoo: VTT Technical Research Centre of Finland. 247 p.Research output: Thesis › Dissertation › Collection of Articles
Open Access -
Chemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells
Ketola, K., Kallioniemi, O. & Iljin, K., 2012, In: PLoS ONE. 7, 12, 51470.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access23 Citations (Scopus) -
C-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells
Björkblom, B., Padzik, A., Mohammad, H., Westerlund, N., Komulainen, E., Hollos, P., Parviainen, L., Papageorgiou, A. C., Iljin, K., Kallioniemi, O., Kallajoki, M., Courtney, M. J., Magar, M., James, P. & Coffey, E. T., 2012, In: Molecular and Cellular Biology. 32, 17, p. 3513-3526 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
40 Citations (Scopus) -
Colon-derived microbial metabolites of dietary phenolic compounds
Aura, A-M., 2012, Flavonoids and Related Compounds: Bioavailability and Function . Spencer, J. P. E. & Crozier, A. (eds.). CRC Press, 32 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Professional
6 Citations (Scopus) -
Current knowledge of railway suicides and trespassing accidents: RESTRAIL Working paper WP1
Silla, A., Rådbo, H., Lukaschek, K., Burkhardt, J. M. & Paran, F., 2012, European Commission EC. 48 p.Research output: Book/Report › Report
Open Access -
Detection of smell print differences between nonmalignant and malignant prostate cells with an electronic nose
Roine, A., Tolvanen, M., Sipiläinen, M., Kumpulainen, P., Helenius, M. A., Lehtimäki, T., Vepsäläinen, J., Keinänen, T. A., Häkkinen, M. R., Koskimäki, J., Veskimäe, E., Tuokko, A., Visakorpi, T., Tammela, T. L., Sioris, T., Paavonen, T., Lekkala, J., Helle, H. & Oksala, N. K. J., 2012, In: Future Oncology. 8, 9, p. 1157-1165Research output: Contribution to journal › Article › Scientific › peer-review
11 Citations (Scopus) -
Differentiation-promoting culture of competent and noncompetent keratinocytes identifies biomarkers for head and neck cancer
Ceder, R., Haig, Y., Merne, M., Hansson, A., Zheng, X., Roberg, K., Nees, M., Iljin, K., Bloor, B. K., Morgan, P. R., Fadeel, B. & Grafström, R., 2012, In: American Journal of Pathology. 180, 2, p. 457-472 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
23 Citations (Scopus) -
Dissecting the molecular mechanisms of breast cancer bone metastasis for therapeutic targeting: Dissertation
Pollari, S., 2012, Turku: University of Turku. 64 p.Research output: Thesis › Dissertation › Collection of Articles
Open Access -
Distinct recycling of active and inactive β1 integrins
Arjonen, A., Alanko, J., Veltel, S. & Ivaska, J., 2012, In: Traffic. 13, 4, p. 610-625Research output: Contribution to journal › Article › Scientific › peer-review
Open Access138 Citations (Scopus) -
Distinct roles of AKT isoforms in regulating β1-integrin activity, migration, and invasion in prostate cancer
Virtakoivu, R., Pellinen, T., Rantala, J. K., Perälä, M. & Ivaska, J., 2012, In: Molecular Biology of the Cell. 23, 17, p. 3357-3369Research output: Contribution to journal › Article › Scientific › peer-review
Open Access55 Citations (Scopus) -
Dynamic thermography, a non-invasive method for targeted evaluation of body surface temperature verified by cold gel stress test
Karhu, J., Kaarre, M., Lasanen, R. & Airaksinen, O., 2012, In: Pain Practice.Research output: Contribution to journal › Article › Scientific › peer-review
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Effects of a catalytic converter on PCDD/F, chlorophenol and PAH emissions in residential wood combustion
Kaivosoja, T., Virén, A., Tissari, J., Ruuskanen, J., Tarhanen, J., Sippula, O. & Jokiniemi, J., 2012, In: Chemosphere. 88, 3, p. 278-285Research output: Contribution to journal › Article › Scientific › peer-review
35 Citations (Scopus) -
Efficiency of log wood combustion affects the toxicological and chemical properties of emission particles
Tapanainen, M., Jalava, P. I., Mäki-Paakkanen, J., Hakulinen, P., Lamberg, H., Ruusunen, J., Tissari, J., Jokiniemi, J. & Hirvonen, M-R., 2012, In: Inhalation Toxicology. 24, 6, p. 343-355Research output: Contribution to journal › Article › Scientific › peer-review
27 Citations (Scopus) -
End-of-Waste criteria for waste-derived aggregates
Hjelmar, O., van der Sloot, H., Comans, R. & Wahlström, M., 2012, WASCON 2012 conference proceedings: Towards effective, durable and sustainable production and use of alternative materials in construction. 11 p.Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
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Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction
Ylipaasto, P., Smura, T., Gopalacharyulu, P., Paananen, A., Seppänen-Laakso, T., Kaijalainen, S., Ahlfors, H., Korsgren, O., Lakey, J. R. T., Lahesmaa, R., Piemonti, L., Oresic, M., Galama, J. & Roivainen, M., 2012, In: Diabetologia. 55, 12, p. 3273-3283 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
34 Citations (Scopus) -
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression
Rafn, B., Nielsen, C. F., Andersen, S. H., Szyniarowski, P., Corcelle-Termeau, E., Valo, E., Fehrenbacher, N., Olsen, C. J., Daugaard, M., Egebjerg, C., Bøttzauw, T., Kohonen, P., Nylandsted, J., Hautaniemi, S., Moreira, J., Jäättelä, M. & Kallunki, T., 2012, In: Molecular Cell. 45, 6, p. 764-776Research output: Contribution to journal › Article › Scientific › peer-review
Open Access82 Citations (Scopus) -
Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis
Pollari, S., Käkönen, S-M., Edgren, H., Wolf, M., Kohonen, P., Sara, H., Guise, T., Nees, M. & Kallioniemi, O., 2012, In: Breast Cancer Research and Treatment. 131, 3, p. 1085-1086 1 p.Research output: Contribution to journal › Other journal contribution › Scientific
1 Citation (Scopus) -
Evaluation of activity and combination strategies with the microtubule-targeting drug sagopilone in breast cancer cell lines
Eschenbrenner, J., Winsel, S., Hammer, S., Sommer, A., Mittelstaedt, K., Drosch, M., Klar, U., Sachse, C., Hannus, M., Seidel, M., Weiss, B., Merz, C., Siemeister, G. & Hoffmann, J., 2012, In: Frontiers in Oncology.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access6 Citations (Scopus) -
Exposure to CeO2 nanoparticles during flame spray process
Leppänen, M., Lyyränen, J., Järvelä, M., Auvinen, A., Jokiniemi, J., Pimenoff, J. & Tuomi, T., 2012, In: Nanotoxicology. 6, 6, p. 643-651 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
19 Citations (Scopus) -
ForestSpeCs findings on byproducts of forest industry: could bark be more valuable than timber?
Hokkanen, H. M. T., Ahlnäs, T., Alakurtti, S., Demidova, N., Fuchs, J., Izotov, D., Kleeberg, H., Koskimies, S., Langat, M., Lynch, J., Menzler-Hokkanen, I., Mulholland, D., Schärer, H-J., Shikov, A., Tamm, L., Tammela, P. & Yli-Kauhaluoma, J., 2012, NWBC 2012: The 4th Nordic Wood Biorefinery Conference. Niemelä, K. (ed.). Espoo: VTT Technical Research Centre of Finland, p. 56-59 (VTT Technology; No. 53).Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Professional
Open Access2 Citations (Scopus) -
Grid and pervasive computing: International Workshops, S3E, HWTS, Doctoral Colloquium, Held in Conjunction with GPC 2011, Oulu, Finland, May 11-13, 2011. Revised Selected Papers
Rautiainen, M. (ed.), Korhonen, T. (ed.), Mutafungwa, E. (ed.), Ovaska, E. (ed.), Katasonov, A. (ed.), Evesti, A. (ed.), Ailisto, H. (ed.), Quigley, A. (ed.), Häkkilä, J. (ed.), Milic-Frayling, N. (ed.) & Riekki, J. (ed.), 2012, Berlin: Springer. 195 p. (Lecture Notes in Computer Science, Vol. 7096).Research output: Book/Report › Book (editor) › Scientific › peer-review
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Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis
Pollari, S., Käkönen, R. S., Mohammad, K. S., Rissanen, J. P., Halleen, J. M., Wärri, A., Nissinen, L., Pihlavisto, M., Marjamäki, A., Perälä, M., Guise, T. A., Kallioniemi, O. & Käkönen, S-M., 2012, In: Molecular Cancer Research. 10, 5, p. 597-604Research output: Contribution to journal › Article › Scientific › peer-review
26 Citations (Scopus) -
HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation
Haapa-Paananen, S., Kiviluoto, S., Waltari, M., Puputti, M., Mpindi, J., Kohonen, P., Tynninen, O., Haapasalo, H., Joensuu, H., Perälä, M. & Kallioniemi, O., 2012, In: Oncogene. 31, 10, p. 1299-1310Research output: Contribution to journal › Article › Scientific › peer-review
19 Citations (Scopus) -
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer
Vainio, P., Mpindi, J-P., Kohonen, P., Fey, V., Mirtti, T., Alanen, K. A., Perälä, M., Kallioniemi, O. & Iljin, K., 2012, In: PLoS ONE. 7, 6, e39801.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access36 Citations (Scopus) -
How to prevent railway suicides and fatalities related to trespassing accidents?
Silla, A., 2012.Research output: Contribution to conference › Conference article › Professional
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Identification of fibroblast growth factor-8b target genes associated with early and late cell cycle events in breast cancer cells
Nilsson, E. M., Brokken, L. J. S., Narvi, E., Kallio, M. & Härkönen, P. L., 2012, In: Molecular and Cellular Endocrinology. 358, 1, p. 104-115Research output: Contribution to journal › Article › Scientific › peer-review
7 Citations (Scopus) -
Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells
Pollari, S., Leivonen, S-K., Perälä, M., Fey, V., Käkönen, S-M. & Kallioniemi, O., 2012, In: PLoS ONE. 7, 5, 9 p., e37361.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access56 Citations (Scopus) -
Identification of novel lignans in the whole grain rye bran by non-targeted LC-MS metabolite profiling
Hanhineva, K., Rogachev, I., Aura, A-M., Aharoni, A., Poutanen, K. & Mykkänen, H., 2012, In: Metabolomics. 8, 3, p. 399-409Research output: Contribution to journal › Article › Scientific › peer-review
23 Citations (Scopus) -
In-depth proteome mining of cultured Catharanthus roseus cells identifies candidate proteins involved in the synthesis and transport of secondary metabolites
Champagne, A., Rischer, H., Oksman-Caldentey, K-M. & Boutry, M., 2012, In: Proteomics. 12, 23-24, p. 3536-3547 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
25 Citations (Scopus) -
Integrated Model of Metabolism and Autoimmune Response in ß-Cell Death and Progression to Type 1 Diabetes
Marinković, T., Sysi-Aho, M. & Orešič, M., 2012, In: PLoS ONE. 7, 12, 51909.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access7 Citations (Scopus) -
Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer: Link to patient survival, hormone receptor status and metabolic profiling
Brockmöller, S. F., Bucher, E., Müller, B. M., Budczies, J., Hilvo, M., Leether Griffin, J., Oresic, M., Kallioniemi, O., Iljin, K., Loibl, S., Darb-Esfahani, S., Sinn, B. V., Klauschen, F., Prinzler, J., Bangemann, N., Ismaeel, F., Fiehn, O., Dietel, M. & Denkert, C., 2012, In: Journal of Proteome Research. 11, 2, p. 850-860 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
56 Citations (Scopus) -
Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling
Paatero, I., Jokilammi, A., Heikkinen, P. T., Iljin, K., Kallioniemi, O., Jones, F. J., Jaakkola, P. M. & Elenius, K., 2012, In: Journal of Biological Chemistry. 287, 13, p. 9659-9671 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
34 Citations (Scopus) -
In vitro microbiotic fermentation causes an extensive metabolite turnover of rye bran phytochemicals
Hanhineva, K., Aura, A-M., Rogachev, I., Matero, S., Skov, T., Aharoni, A., Poutanen, K. & Mykkänen, H., 2012, In: PLoS ONE. 7, 6, 10 p., e39322.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access14 Citations (Scopus) -
In vitro toxicological characterization of particulate emissions from residential biomass heating systems based on old and new technologies
Jalava, P. I., Happo, M. S., Kelz, J., Brunner, T., Hakulinen, P., Mäki-Paakkanen, J., Hukkanen, A., Jokiniemi, J., Obernberger, I. & Hirvonen, M-R., 2012, In: Atmospheric Environment. 50, p. 24-35Research output: Contribution to journal › Article › Scientific › peer-review
53 Citations (Scopus) -
Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models
Härmä, V., Knuuttila, M., Virtanen, J., Mirtti, T., Kohonen, P., Kovanen, P., Happonen, A., Kaewphan, S., Ahonen, I., Kallioniemi, O., Grafström, R., Lötjönen, J. & Nees, M., 2012, In: Oncogene. 31, 16, p. 2075-2089Research output: Contribution to journal › Article › Scientific › peer-review
Open Access30 Citations (Scopus) -
Main characteristics of train–pedestrian fatalities on Finnish railroads
Silla, A. & Luoma, J., 2012, In: Accident Analysis and Prevention. 45, p. 61-66 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access24 Citations (Scopus) -
Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
Jerby, L., Wolf, L., Denkert, C., Stein, G. Y., Hilvo, M., Orešič, M., Geiger, T. & Ruppin, E., 2012, In: Cancer Research. 72, 22, p. 5712-5720Research output: Contribution to journal › Article › Scientific › peer-review
88 Citations (Scopus) -
Metabolomics in the studies of islet autoimmunity and type 1 diabetes
Orešič, M., 2012, In: Review of Diabetic Studies. 9, 4, p. 236-247Research output: Contribution to journal › Article › Scientific › peer-review
15 Citations (Scopus) -
Metabolomics of human breast cancer: New approaches for tumor typing and biomarker discovery
Denkert, C., Bucher, E., Hilvo, M., Salek, R., Orešič, M., Griffin, J., Brockmöller, S., Klauschen, F., Loibl, S., Barubal, D. K., Budczies, J., Iljin, K., Nekljudova, V. & Fiehn, O., 2012, In: Genome Medicine. 4, 9 p., 37.Research output: Contribution to journal › Review Article › peer-review
Open Access73 Citations (Scopus) -
Method for the evaluation of measures targeted to prevent railway suicides and trespassing accidents: Merged RESTRAIL Deliverable D2.1 & D3.1
Kallberg, V-P., Ryan, B., Bruyelle, J-L. & El-Koursi, E-M., 2012, European Commission EC. 38 p.Research output: Book/Report › Report
Open Access -
Metrics driven security management framework for ehealth digital ecosystem focusing on chronic diseases
Savola, R. & Sihvonen, M., 2012, Proceedings of the International Conference on Management of Emergent Digital EcoSystems, MEDES 2012. New York, NY, USA: Association for Computing Machinery ACM, p. 75-79Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review
6 Citations (Scopus) -
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
Sebastián, D., Hernández-Alvarez, M. I., Segalés, J., Sorianello, E., Muñoz, J. P., Sala, D., Waget, A., Liesa, M., Paz, J. C., Gopalacharyulu, P., Orešič, M., Pich, S., Burcelin, R., Palacín, M. & Zorzano, A., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5523-5528Research output: Contribution to journal › Article in a proceedings journal › Scientific › peer-review
350 Citations (Scopus) -
Monensin Induced Oxidative Stress Reduces Prostate Cancer Cell Migration and Cancer Stem Cell Population
Ketola, K., Vuoristo, A., Oresic, M., Kallioniemi, O. & Iljin, K., 2012, Oxidative Stress and Diseases. Lushchak, V. (ed.). InTech, p. 521-540Research output: Chapter in Book/Report/Conference proceeding › Chapter or book article › Scientific › peer-review
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Multi-phase thermodynamic modelling of pulp suspensions: Application to a papermaking process
Kalliola, A., Pajarre, R., Koukkari, P., Hakala, J. & Kukkamäki, E., 2012, In: Nordic Pulp and Paper Research Journal. 27, 3, p. 613-620 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access5 Citations (Scopus)