Find Research Outputs

Search concepts
Selected filters
2019
1 Citation (Scopus)

Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation

Koistinen, V. M., Kärkkäinen, O., Borewicz, K., Zarei, I., Jokkala, J., Micard, V., Rosa-Sibakov, N., Auriola, S., Aura, A. M., Smidt, H. & Hanhineva, K., 10 Jul 2019, In : Microbiome. 7, 1, 103.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Betaine
Fermentation
Diet
Microbiota
Ruminococcus
5 Citations (Scopus)

Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability?

Bento-Silva, A., Koistinen, V. M., Mena, P., Bronze, M. R., Hanhineva, K., Sahlstrøm, S., Kitrytė, V., Moco, S. & Aura, A. M., 1 Jan 2019, In : European Journal of Nutrition.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
Insurance Benefits
Food
Food Handling
Microbiota
Health
2 Citations (Scopus)

Factors Explaining Interpersonal Variation in Plasma Enterolactone Concentrations in Humans

Hålldin, E., Eriksen, A. K., Brunius, C., da Silva, A. B., Bronze, M., Hanhineva, K., Aura, A. M. & Landberg, R., 28 Feb 2019, In : Molecular Nutrition and Food Research. 63, 16, 1801159.

Research output: Contribution to journalReview ArticleScientificpeer-review

lignans
intestinal microorganisms
Lignans
food composition
smoking (food products)
1 Citation (Scopus)

Mastication-induced release of compounds from rye and wheat breads to saliva

Pentikäinen, S., Koistinen, V., Kolehmainen, M., Poutanen, K., Hanhineva, K. & Aura, A. M., 1 Jan 2019, In : Food Chemistry. 270, p. 502-508 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Mastication
Bread
mastication
saliva
Saliva

Targeting the delivery of dietary plant bioactives to those who would benefit most: From science to practical applications

de Roos, B., Aura, A. M., Bronze, M., Cassidy, A., Conesa, M. T. G., Gibney, E. R., Greyling, A., Kaput, J., Kerem, Z., Knežević, N., Kroon, P., Landberg, R., Manach, C., Milenkovic, D., Rodriguez-Mateos, A., Tomás-Barberán, F. A., van de Wiele, T. & Morand, C., Nov 2019, In : European Journal of Nutrition. 58, Supplement 2, p. 65-73 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
Food
Food Industry
Diet
Food Quality
Translational Medical Research
2018
2 Citations (Scopus)

Interlaboratory coverage test on plant food bioactive compounds and their metabolites by mass spectrometry-based untargeted metabolomics

Koistinen, V. M., da Silva, A. B., Abrankó, L., Low, D., Villalba, R. G., Barberán, F. T., Landberg, R., Savolainen, O., Alvarez-Acero, I., de Pascual-Teresa, S., Van Poucke, C., Almeida, C., Petrásková, L., Valentová, K., Durand, S., Wiczkowski, W., Szawara-Nowak, D., González-Domínguez, R., Llorach, R., Andrés-Lacueva, C. & 5 others, Aura, A. M., Seppänen-Laakso, T., Hanhineva, K., Manach, C. & Bronze, M. R., 1 Sep 2018, In : Metabolites. 8, 3, 46.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Edible Plants
Metabolomics
Metabolites
Mass spectrometry
Mass Spectrometry
2 Citations (Scopus)

In Vitro Gut Metabolism of [U-13C]-Quinic Acid, The Other Hydrolysis Product of Chlorogenic Acid

Naranjo Pinta, M., Montoliu, I., Aura, A. M., Seppänen-Laakso, T., Barron, D. & Moco, S., 1 Nov 2018, In : Molecular Nutrition and Food Research. 62, 22, 1800396.

Research output: Contribution to journalArticleScientificpeer-review

Caffeic Acids
Quinic Acid
Chlorogenic Acid
quinic acid
chlorogenic acid
12 Citations (Scopus)

Metabolic profiling of sourdough fermented wheat and rye bread

Koistinen, V. M., Mattila, O., Katina, K., Poutanen, K., Aura, A. M. & Hanhineva, K., 1 Dec 2018, In : Scientific Reports. 8, 1, 5684.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
sourdough
metabolomics
rye
breads
whole grain foods
3 Citations (Scopus)
Open Access
Plant Cells
Food
Vaccinium vitis-idaea
Fruit
Hydrolysis
2017
14 Citations (Scopus)

Effect of bioprocessing on the in vitro colonic microbial metabolism of phenolic acids from rye bran fortified breads

Koistinen, V., Nordlund, E., Katina, K., Mattila, I., Poutanen, K., Hanhineva, K. & Aura, A-M., 2017, In : Journal of Agricultural and Food Chemistry. 65, 9, p. 1854-1864 11 p.

Research output: Contribution to journalArticleScientificpeer-review

rye bran
bioprocessing
Bread
phenolic acids
ferulic acid
3 Citations (Scopus)

Interactions of Insoluble Residue from Enzymatic Hydrolysis of Brewer's Spent Grain with Intestinal Microbiota in Mice

Maukonen, J., Aura, A. M., Niemi, P., Raza, G. S., Niemelä, K., Walkowiak, J., Mattila, I., Poutanen, K., Buchert, J. & Herzig, K. H., 10 May 2017, In : Journal of Agricultural and Food Chemistry. 65, 18, p. 3748-3756 9 p.

Research output: Contribution to journalArticleScientificpeer-review

spent grains
brewers grains
Enzymatic hydrolysis
enzymatic hydrolysis
Nutrition
2016
9 Citations (Scopus)

Birch pulp xylan works as a food hydrocolloid in acid milk gels and is fermented slowly in vitro

Rosa-Sibakov, N., Hakala, T., Sozer, N., Nordlund, E., Poutanen, K. & Aura, A-M., 2016, In : Carbohydrate Polymers. 154, p. 305-312

Research output: Contribution to journalArticleScientificpeer-review

Xylans
Colloids
Pulp
Gels
Acids
19 Citations (Scopus)

Metabolic transformations of dietary polyphenols: Comparison between in vitro colonic and hepatic models and in vivo urinary metabolites

Vetrani, C., Rivellese, A. A., Annuzzi, G., Adiels, M., Borén, J., Mattila, I., Oresic, M. & Aura, A-M., 2016, In : Journal of Nutritional Biochemistry. 33, p. 111-118

Research output: Contribution to journalArticleScientificpeer-review

Polyphenols
Metabolites
Colon
Liver
Metabolism

Phenolic Acids in Rye

Aura, A-M., 2016, Rye and Health. Poutanen, K. & Åman, P. (eds.). Elsevier, p. 109-119

Research output: Chapter in Book/Report/Conference proceedingChapter or book articleProfessional

10 Citations (Scopus)

Structure of brewer's spent grain lignin and its interactions with gut microbiota in vitro

Ohra-aho, T., Niemi, P., Aura, A-M., Orlandi, M., Poutanen, K., Buchert, J. & Tamminen, T., 2016, In : Journal of Agricultural and Food Chemistry. 64, 4, p. 812-820

Research output: Contribution to journalArticleScientificpeer-review

spent grains
brewers grains
Lignin
intestinal microorganisms
lignin
2015
8 Citations (Scopus)

Bilberry and bilberry press cake as sources of dietary fibre

Aura, A-M., Holopainen-Mantila, U., Sibakov, J., Kössö, T., Mokkila, M. & Kaisa, P., Jan 2015, In : Food and Nutrition Research. 59, 1 p., 28367.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Vaccinium myrtillus
oilseed cakes
bilberries
Dietary Fiber
dietary fiber

Effects of ellagitannin rich berries on blood lipid profiles, gut microbiota and metabolism of phenolic compounds in metabolic syndrome

Puupponen-Pimiä, R., Seppänen-Laakso, T., Maukonen, J., Nohynek, L., Tómas-Barberán, F. A., Törrönen, R., Kolehmainen, M., Kankainen, M., Espín, J. C., Aura, A-M., Poutanen, K., Leppänen, T., Moilanen, E. & Oksman-Caldentey, K-M., 2015, In : Dosis. 33, 3, p. 55-76

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Fruit
Lipids
Hydrolyzable Tannins
8-epi-prostaglandin F2alpha
Blood Pressure
2014
21 Citations (Scopus)

Effects of wheat and rye bread structure on mastication process and bolus properties

Pentikäinen, S., Sozer, N., Närväinen, J., Ylätalo, S., Teppola, P., Jurvelin, J., Holopainen-Mantila, U., Törrönen, R., Aura, A-M. & Poutanen, K., Dec 2014, In : Food Research International. 66, p. 356-364 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Mastication
Bread
mastication
rye
breads

In-vitro co-culture for matching Diabetes Type II changes with adipocyte lipidome

Kolari, K., Virtanen, J., Aura, A-M., Nygren, H. & Nees, M., 2014.

Research output: Contribution to conferenceOther conference contributionScientific

1 Citation (Scopus)

In vitro colon model to study metabolic syndrome

Aura, A-M., 2014, A Systems Biology Approach to Study Metabolic Syndrome. Orešič, M. & Vidal-Puig, A. (eds.). Springer, p. 251 - 278

Research output: Chapter in Book/Report/Conference proceedingChapter or book articleProfessional

Colon
Biomarkers
Diet
Food and Beverages
Metabolomics
108 Citations (Scopus)

In vitro models for studying secondary plant metabolite digestion and bioaccessibility

Alminger, M., Aura, A-M., Bohn, T., Dufour, C., El, S. N., Gomes, A., Karakaya, S., Martinez-Cuesta, M. C., Mcdougall, G. J., Requena, T. & Santos, C. N., 2014, In : Comprehensive Reviews in Food Science and Food Safety. 13, 4, p. 413-436 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Digestion
digestion
metabolites
Phytochemicals
Bile Acids and Salts
19 Citations (Scopus)

Isoenergetic diets differing in their n-3 fatty acid and polyphenol content reflect different plasma and HDL-fraction lipidomic profiles in subjects at high cardiovascular risk

Bondia-Pons, I., Pöhö, P., Bozzetto, L., Vetrani, C., Patti, L., Aura, A-M., Annuzzi, G., Hyötyläinen, T., Rivellese, A. A. & Oresic, M., 2014, In : Molecular Nutrition and Food Research. 58, 9, p. 1873-1882 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Omega-3 Fatty Acids
Polyphenols
omega-3 fatty acids
polyphenols
Diet
15 Citations (Scopus)

Phenolic metabolites as compliance biomarker for polyphenol intake in a randomized controlled human intervention

Vetrani, C., Rivellese, A. A., Annuzzi, G., Mattila, I., Meudec, E., Hyötyläinen, T., Oresic, M. & Aura, A-M., 2014, In : Food Research International. 63, Part B, p. 233-238 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Polyphenols
compliance
Compliance
biomarkers
polyphenols
2013

Cereal fractions rich in fibres and antioxidants: Does structure have an impact on health effects?

Micard, V., Rosa, N., Pekkinen, J., Dufour, C., Aura, A-M., Hanhiheva, K. & Poutanen, K., 2013.

Research output: Contribution to conferenceOther conference contributionScientific

45 Citations (Scopus)
rye bran
bioprocessing
ferulic acid
in vitro digestibility
Dietary Fiber
45 Citations (Scopus)

Characterization of microbial metabolism of Syrah grape products in an in vitro colon model using targeted and non-targeted analytical approaches

Aura, A-M., Mattila, I., Hyötyläinen, T., Gopalacharyulu, P., Cheynier, V., Souquet, J-M., Bes, M., Le Bourvellec, C., Guyot, S. & Oresic, M., 2013, In : European Journal of Nutrition. 52, 2, p. 833-846 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Vitis
Proanthocyanidins
Wine
Colon
Gas Chromatography-Mass Spectrometry
24 Citations (Scopus)

Comparison of postprandial phenolic acid excretions and glucose responses after ingestion of breads with bioprocessed or native rye bran

Lappi, J., Aura, A-M., Katina, K., Nordlund, E., Kolehmainen, M., Mykkänen, H. & Poutanen, K., 2013, In : Food and Function. 4, 6, p. 972-981 9 p.

Research output: Contribution to journalArticleScientificpeer-review

rye bran
ferulic acid
Bread
phenolic acids
breads

Detection and consequences of exposure to polyphenol-rich foods and beverages and their colonic microbial metabolites in vivo and in vitro

Aura, A-M., Vetrani, C., Mattila, I., Annuzzi, G., Rivellese, A., Cascante, M., Miranda, A., Selivanov, V., Borén, J. & Oresic, M., 2013.

Research output: Contribution to conferenceOther conference contributionScientific

Detection and consequences of exposure to polyphenol-rich foods and beverages and their colonic microbial metabolites in vivo and in vitro

Aura, A-M., Vetrani, C., Mattila, I., Annuzzi, G., Rivellese, A., Cascante, M., Miranda, A., Marin, S., Selivanov, V., Borén, J. & Oresic, M., 2013.

Research output: Contribution to conferenceOther conference contributionScientific

19 Citations (Scopus)

Effects of disintegration on in vitro fermentation and conversion patterns of wheat aleurone in a metabolical colon model

Rosa, N. N., Aura, AM., Saulnier, L., Holopainen-Mantila, U., Poutanen, K. & Micard, V., 2013, In : Journal of Agricultural and Food Chemistry. 61, p. 5805-5816 12 p.

Research output: Contribution to journalArticleScientificpeer-review

ferulic acid
Volatile Fatty Acids
Disintegration
short chain fatty acids
Fermentation
12 Citations (Scopus)

Interactions of a lignin-rich fraction from Brewer's spent grain with gut microbiota in vitro

Niemi, P., Aura, A-M., Maukonen, J., Smeds, A. I., Mattila, I., Niemelä, K., Tamminen, T., Faulds, C. B., Buchert, J. & Poutanen, K., 2013, In : Journal of Agricultural and Food Chemistry. 61, 27, p. 6754-6762 8 p.

Research output: Contribution to journalArticleScientificpeer-review

spent grains
brewers grains
Lignin
intestinal microorganisms
lignin
2012
5 Citations (Scopus)

Colon-derived microbial metabolites of dietary phenolic compounds

Aura, A-M., 2012, Flavonoids and Related Compounds: Bioavailability and Function . Spencer, J. P. E. & Crozier, A. (eds.). CRC Press, 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter or book articleProfessional

Edible Plants
Colon
Fruit
Fabaceae
Vegetables
20 Citations (Scopus)

Identification of novel lignans in the whole grain rye bran by non-targeted LC-MS metabolite profiling

Hanhineva, K., Rogachev, I., Aura, A-M., Aharoni, A., Poutanen, K. & Mykkänen, H., 2012, In : Metabolomics. 8, 3, p. 399-409

Research output: Contribution to journalArticleScientificpeer-review

Lignans
Metabolites
Health
Metabolomics
Plant Extracts

In vitro fermentation of a lignin-rich fraction extracted from brewer’s spent grain

Niemi, P., Aura, A-M., Smeds, A., Tamminen, T., Faulds, G., Poutanen, K. & Buchert, J., 2012, Lignobiotech II Symposium.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

14 Citations (Scopus)

In vitro microbiotic fermentation causes an extensive metabolite turnover of rye bran phytochemicals

Hanhineva, K., Aura, A-M., Rogachev, I., Matero, S., Skov, T., Aharoni, A., Poutanen, K. & Mykkänen, H., 2012, In : PLoS ONE. 7, 6, 10 p., e39322.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
rye bran
Phytochemicals
Metabolites
Fermentation
phytopharmaceuticals
2011
124 Citations (Scopus)

Bioprocessing of wheat bran in whole wheat bread increases the bioavailability of phenolic acids in men and exerts anti-inflammatory effects ex vivo

Mateo Anson, N., Aura, A-M., Selinheimo, E., Mattila, I., Poutanen, K., van den Bergh, R., Havenaar, R., Bast, A. & Haenen, G. R. M. M., 2011, In : Journal of Nutrition. 141, 1, p. 137-143

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Bread
Dietary Fiber
Biological Availability
Triticum
Anti-Inflammatory Agents

Brewer's grain lignin: a potential value-added product for food and non-food applications

Niemi, P., Buchert, J., Wilhelmson, A., Saarela, M., Aura, A-M., Tamminen, T. & Poutanen, K., 2011, International Congress of the European Brewery Convention 2011. p. 481

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

28 Citations (Scopus)

Drug metabolome of the Simvastatin formed by human intestinal microbiota in vitro

Aura, A-M., Mattila, I., Hyötyläinen, T., Gopalacharyulu, P., Bounsaythip, C., Oresic, M. & Oksman-Caldentey, K-M., 2011, In : Molecular bioSystems. 7, 2, p. 437-446

Research output: Contribution to journalArticleScientificpeer-review

Simvastatin
Metabolome
Colon
Metabolomics
Pharmaceutical Preparations
49 Citations (Scopus)

Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread

Bondia-Pons, I., Nordlund, E., Mattila, I., Katina, K., Aura, A-M., Kolehmainen, M., Oresic, M., Mykkänen, H. & Poutanen, K., 2011, In : Nutrition Journal. 10, 116, 116.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Endosperm
Metabolome
Bread
Triticum
Healthy Volunteers

Prediction of food-related microbial metabolome derived from polyphenol-rich foods

Aura, A-M., Mattila, I., Hyötyläinen, T., Gopalacharyulu, P. & Oresic, M., 2011, Metabomeeting 2011. p. 138-139

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientific

50 Citations (Scopus)

Qualitative characterization of benzoxazinoid derivatives in whole grain rye and wheat by LC-MS metabolite profiling

Hanhineva, K., Rogachev, I., Aura, A-M., Aharoni, A., Poutanen, K. & Mykkänen, H., 7 Jan 2011, In : Journal of Agricultural and Food Chemistry. 59, 3, p. 921-927

Research output: Contribution to journalArticleScientificpeer-review

Benzoxazines
benzoxazinoids
whole grain foods
Metabolites
rye
2010

Benefits of wheat processing on the bioavailability of phenolic acids in relation to potential health effects

Mateo Anson, A., Havenaar, R., Aura, A-M., Selinheimo, E., Bast, A. & Haenen, G., 2010, Final HEALTHGRAIN Conference Enhancing Health Benefits of Cereal Foods: Results, Perspectives and Challenges. Espoo: VTT Technical Research Centre of Finland, 37

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Comprehensive analysis of Syrah grape proanthocyanidin conversion to phenolic acids by GCXGC-TOFMS

Mattila, I., Aura, A-M., Hyötyläinen, T., Gopalacharuylu, P., Tang, J., Sysi-Aho, M. & Oresic, M., 2010, Abstract book, 34 International Symposium on Capillary Chromatography and 7th GCxGC Symposium. Kortrijk, 326

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Non-targeted metabolite profiling of the phytochemicals of rye and effects of microbiota on their composition in in vitro colon model

Hanhineva, K., Aura, A-M., Rogachev, I., Aharoni, A., Mykkänen, H. & Poutanen, K., 2010, Metabolomics 2010, abstract book: Breakthroughs in plant, microbial and human biology, clinical and nutritional research, and biomarker discovery . p. 177

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Use of xylanases and oxidative enzymes to improve gluten network properties in whole grain wheat bread

Selinheimo, E., Katina, K., Aura, A-M., Lehtinen, P. & Poutanen, K., 2010, Final HealthGrain Conference: Enhancing Health Benefits of Cereal Foods - Results, Perspectives and Challenges. Espoo: VTT Technical Research Centre of Finland, p. 101

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific