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2019

Development of microtiter plate scale CRISPR/Cas9 transformation method for Aspergillus niger based on in vitro assembled ribonucleoprotein complexes

Kuivanen, J., Korja, V., Holmström, S. & Richard, P., 15 Mar 2019, In : Fungal Biology and Biotechnology. 6, 3, 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Ribonucleoproteins
Aspergillus niger
Fungi
Guide RNA

Microbial hexuronate catabolism in biotechnology

Kuivanen, J., Biz, A. & Richard, P., 2019, In : AMB Express. 9, 1, 11 p., 16.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
Iduronic Acid
Glucuronic Acid
Biotechnology
Biomass
Polysaccharides
2018
3 Citations (Scopus)

NADPH-dependent 5-keto-D-gluconate reductase is a part of the fungal pathway for D-glucuronate catabolism

Kuivanen, J. & Richard, P., 1 Jan 2018, In : FEBS Letters. 592, 1, p. 71-77 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Glucuronic Acid
NADP
Fungi
Clustered Regularly Interspaced Short Palindromic Repeats
Pentoses
2017
9 Citations (Scopus)

Clustered genes encoding 2-keto-L-gulonate reductase and L-idonate 5-dehydrogenase in the novel fungal D-glucuronic acid pathway

Kuivanen, J., Arvas, M. & Richard, P., 2017, In : Frontiers in Microbiology. 8, FEB, 10 p., 225.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Glucuronic Acid
Oxidoreductases
NADP
NAD
Adhesives
3 Citations (Scopus)

Conversion of citric pectin into D-galacturonic acid with high substrate loading using a fermented solid with pectinolytic activity

Leh, D. S., Biz, A., de Paula, D. H. F., Richard, P., Gonçalves, A. G., Noseda, M. D., Mitchell, D. A. & Kriegera, N., 2017, In : Biocatalysis and Agricultural Biotechnology. 11, p. 214-219 6 p.

Research output: Contribution to journalArticleScientificpeer-review

galacturonic acid
pectins
Acids
Citrus
Pulp
2016
12 Citations (Scopus)

A novel pathway for fungal D-glucuronate catabolism contains an L-idonate forming 2-keto-L-gulonate reductase

Kuivanen, J., Sugai-Guérios, M. H., Arvas, M. & Richard, P., 2016, In : Scientific Reports. 6, 26329.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Aspergillus niger
metabolism
enzymes
gene deletion
histidine
2 Citations (Scopus)

Engineering a filamentous fungus for l-rhamnose extraction

Kuivanen, J. & Richard, P., 2016, In : AMB Express. 6, 27

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Rhamnose
Fungi
Biomass
Hesperidin
Rutin
35 Citations (Scopus)

Engineering Aspergillus niger for galactaric acid production: elimination of galactaric acid catabolism by using RNA sequencing and CRISPR/Cas9

Kuivanen, J., Wang, J. & Richard, P., 2016, In : Microbial Cell Factories. 15, 210.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
RNA Sequence Analysis
Aspergillus niger
Aspergillus
RNA
8 Citations (Scopus)

The introduction of the fungal D-galacturonate pathway enables the consumption of D-galacturonic acid by Saccharomyces cerevisiae

Biz, A., Sugai-Guérios, M. H., Kuivanen, J., Maaheimo, H., Krieger, N., Mitchell, D. A. & Richard, P., 2016, In : Microbial Cell Factories. 15, 144

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Yeast
Saccharomyces cerevisiae
Pulp
Acids
Sugar beets
2015
18 Citations (Scopus)

Metabolic engineering of the fungal D-galacturonate pathway for L-ascorbic acid production

Kuivanen, J., Richard, P. & Penttilä, M., 2015, In : Microbial Cell Factories. 14, 9 p., 2.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Metabolic engineering
Metabolic Engineering
Ascorbic acid
Ascorbic Acid
Acids
19 Citations (Scopus)

Overexpression of PAD1 and FDC1 results in significant cinnamic acid decarboxylase activity in Saccharomyces cerevisiae

Richard, P., Viljanen, K. & Penttilä, M., 2015, In : AMB Express. 5, 12, 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Styrene
Saccharomyces cerevisiae
ferulic acid
Phenylalanine Ammonia-Lyase
Coumaric Acids
2014
9 Citations (Scopus)

Categorisation of sugar acid dehydratases in Aspergillus niger

Motter, F. A., Kuivanen, J., Keränen, H., Hilditch, S., Penttilä, M. & Richard, P., 1 Mar 2014, In : Fungal Genetics and Biology. 64, p. 67-72 6 p.

Research output: Contribution to journalArticleScientificpeer-review

galactonate dehydratase
Hydro-Lyases
Sugar Acids
Aspergillus niger
Proteins
14 Citations (Scopus)

Conversion of orange peel to L-galactonic acid in a consolidated process using engineered strains of Aspergillus niger

Kuivanen, J., Dantas, H., Mojzita, D., Mallmann, E., Biz, A., Krieger, N., Mitchell, D. & Richard, P., 2014, In : AMB Express. 4, 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Aspergillus niger
Citrus
Hydrolysis
Fermentation
Industry
6 Citations (Scopus)

Effect of C-Terminal Protein Tags on Pentitol and l-Arabinose Transport by Ambrosiozyma monospora Lat1 and Lat2 Transporters in Saccharomyces cerevisiae

Londesborough, J., Richard, P., Valkonen, M. & Viljanen, K., 2014, In : Applied and Environmental Microbiology. 80, 9, p. 2737-2745

Research output: Contribution to journalArticleScientificpeer-review

Arabinose
arabinose
Protein C
Saccharomyces cerevisiae
transporters
16 Citations (Scopus)

Pectinase activity determination: An early deceleration in the release of reducing sugars throws a spanner in the works!

Biz, A., Farias, F. C., Motter, F. A., De Paula, D. H., Richard, P., Krieger, N. & Mitchell, D. A., 2014, In : PLoS ONE. 9, 10, e109529.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Polygalacturonase
Deceleration
polygalacturonase
reducing sugars
Sugars
5 Citations (Scopus)

Purification, crystallization and preliminary X-ray diffraction analysis of a novel keto-deoxy-D-galactarate (KDG) dehydratase from Agrobacterium tumefaciens

Taberman, H., Andberg, M., Parkkinen, T., Richard, P., Hakulinen, N., Koivula, A. & Rouvinen, J., 2014, In : Acta Crystallographica Section F: Structural Biology Communications. 70, p. 49-52 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Hydro-Lyases
Agrobacterium tumefaciens
Crystallization
purification
X-Ray Diffraction
2 Citations (Scopus)

The industrial potential of bio-based glycolic acid and polyglycolic acid: Short survey

Gädda, T. M., Pirttimaa, M. M., Koivistoinen, O., Richard, P., Penttilä, M. & Harlin, A., 1 Jan 2014, In : Appita Journal. 67, 1, 1 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Acids
Packaging
Fermentation
Carbon footprint
Consumer products
5 Citations (Scopus)

The yjjN of E. coli codes for an l-galactonate dehydrogenase and can be used for quantification of l-galactonate and l-gulonate

Kuivanen, J. & Richard, P., 2014, In : Applied Biochemistry and Biotechnology. 173, 7, p. 1829-1835 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Escherichia coli
Oxidoreductases
Gene encoding
Metabolic Networks and Pathways
Metabolism
2013
10 Citations (Scopus)

A novel L-xylulose reductase essential for L-arabinose catabolism in Trichoderma reesei

Metz, B., Mojzita, D., Herold, S., Kubicek, C. P., Richard, P. & Seiboth, B., 2013, In : Biochemistry. 52, 14, p. 2453-2460 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Xylulose
Arabinose
Trichoderma
Oxidoreductases
Xylitol
55 Citations (Scopus)

Glycolic acid production in the engineered yeasts Saccharomyces cerevisiae and Kluyveromyces lactis

Koivistoinen, O. M., Kuivanen, J., Barth, D., Turkia, H., Pitkänen, J. P., Penttilä, M. & Richard, P., 23 Sep 2013, In : Microbial Cell Factories. 12, 1, 82.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
glycolic acid
Kluyveromyces
Yeast
Saccharomyces cerevisiae
Yeasts

Identification and characterization of enzymes involved in the oxidative D-galacturonic acid pathway

Koivula, A., Andberg, M., Maaheimo, H., Boer, H., Mojzita, D., Wiebe, M., Richard, P., Parkkinen, T., Taberman, H., Rouvinen, J. & Penttilä, M., 2013.

Research output: Contribution to conferenceConference AbstractScientific

2012
15 Citations (Scopus)

Characterisation of the gene cluster for l-rhamnose catabolism in the yeast Scheffersomyces (Pichia) stipitis

Koivistoinen, O. M., Arvas, M., Headman, J. R., Andberg, M., Penttilä, M., Jeffries, T. W. & Richard, P., 15 Jan 2012, In : Gene. 492, 1, p. 177-185 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Rhamnose
Pichia
Multigene Family
Yeasts
Transcription Factors
24 Citations (Scopus)
Agrobacterium tumefaciens
uronate dehydrogenase
Lactones
mandelate racemase
Enzymes
34 Citations (Scopus)

Engineering filamentous fungi for conversion of d-galacturonic acid to L-galactonic acid

Kuivanen, J., Mojzita, D., Wang, Y., Hilditch, S., Penttilä, M., Richard, P. & Wiebe, M. G., 1 Dec 2012, In : Applied and Environmental Microbiology. 78, 24, p. 8676-8683

Research output: Contribution to journalArticleScientificpeer-review

Open Access
galacturonic acid
Aspergillus niger
galactonate dehydratase
engineering
Fungi

Engineering Saccharomyces cerevisiae for production of glycolic acid

Koivistoinen, O., Kuivanen, J., Penttilä, M. & Richard, P., 2012.

Research output: Contribution to conferenceConference PosterScientific

glycolic acid
Saccharomyces cerevisiae
engineering
glyoxylate cycle
NADP (coenzyme)
16 Citations (Scopus)
Aspergillus niger
Galactitol
Galactose
Oxidoreductases
Xylose
15 Citations (Scopus)

L-xylo-3-hexulose reductase is the missing link in the oxidoreductive pathway for D-galactose catabolism in filamentous fungi

Mojzita, D., Herold, S., Metz, B., Seiboth, B. & Richard, P., 2012, In : Journal of Biological Chemistry. 287, 31, p. 26010-26018 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Fungi
Galactose
Oxidoreductases
Sorbitol
Galactitol
15 Citations (Scopus)

Sorbitol dehydrogenase of Aspergillus niger, SdhA, is part of the oxido-reductive d-galactose pathway and essential for d-sorbitol catabolism

Koivistoinen, O. M., Richard, P., Penttilä, M., Ruohonen, L. & Mojzita, D., 17 Feb 2012, In : FEBS Letters. 586, 4, p. 378-383 6 p.

Research output: Contribution to journalArticleScientificpeer-review

L-Iditol 2-Dehydrogenase
Sorbitol
Aspergillus niger
Aspergillus
Galactose
2011
20 Citations (Scopus)

Cloning of two genes (LAT1,2) encoding specific l-arabinose transporters of the l-arabinose fermenting yeast ambrosiozyma monospora

Verho, R., Penttilä, M. & Richard, P., 1 Jul 2011, In : Applied Biochemistry and Biotechnology. 164, 5, p. 604-611 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Arabinose
Cloning
Yeast
Organism Cloning
Genes

Oxido-reductive metabolism of L-arabinose and D-galactose in filamentous fungi: Metabolic crosstalk versus specific enzymes

Mojzita, D., Koivistoinen, O., Vuoristo, K., Ruohonen, L., Penttilä, M. & Richard, P., 2011, 26th Fungal Genetics Conference: Program and Abstracts. 328. (Fungal Genetics Reports; No. Supplement, Vol. 58).

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Open Access
arabinose
galactose
fungi
metabolism
enzymes

Sorbitol dehydrogenase as a part of Aspergillus niger D-galactose catabolism

Koivistoinen, O., Richard, P., Penttilä, M. & Mojzita, D., 2011, 26th Fungal Genetics Conference at Asilomar March 15-20, 2011. Genetics Society of America, p. 204 359. (Fungal Genetics Reports; No. Supplement, Vol. 58).

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Open Access
L-iditol dehydrogenase
Aspergillus niger
galactose
metabolism
arabinose

The additional D-galacturonate reductase genes in Aspergillus niger and Hypocrea jecorina

Kuivanen, J., Hilditch, S., Mojzita, D., Penttilä, M. & Richard, P., 2011, 26th Fungal Genetics Conference at Asilomar March 15-20, 2011. Genetics Society of America, p. 205 362. (Fungal Genetics Reports; No. Supplement, Vol. 58).

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Trichoderma reesei
Aspergillus niger
pectins
genes
glyceraldehyde
2010

Engineering D-galacturonic acid catabolism in mold

Richard, P., 2010.

Research output: Contribution to conferenceConference articleScientific

35 Citations (Scopus)

Identification in Agrobacterium tumefaciens of the D-galacturonic acid dehydrogenase gene

Boer, H., Maaheimo, H., Koivula, A., Penttilä, M. & Richard, P., 1 Apr 2010, In : Applied Microbiology and Biotechnology. 86, 3, p. 901-909

Research output: Contribution to journalArticleScientificpeer-review

Agrobacterium tumefaciens
Oxidoreductases
NAD
uronate dehydrogenase
Lactones
31 Citations (Scopus)

Identification of an L-arabinose reductase gene in Aspergillus niger and its role in L-arabinose catabolism

Mojzita, D., Penttilä, M. & Richard, P., 30 Jul 2010, In : Journal of Biological Chemistry. 285, 31, p. 23622-23628 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Arabinose
Aspergillus niger
Aspergillus
Xylose
Oxidoreductases
47 Citations (Scopus)

Metabolie engineering of fungal strains for conversion of D-galacturonate to meso-Galactarate

Mojzita, D., Wiebe, M., Hilditch, S., Boer, H., Penttilä, M. & Richard, P., 1 Jan 2010, In : Applied and Environmental Microbiology. 76, 1, p. 169-175

Research output: Contribution to journalArticleScientificpeer-review

Aspergillus niger
catabolism
Oxidoreductases
engineering
gene

Saccharomyces cerevisiae engineered to produce D-xylonate

Toivari, M., Ruohonen, L., Richard, P., Penttilä, M. & Wiebe, M., 2010.

Research output: Contribution to conferenceConference articleScientific

38 Citations (Scopus)

Saccharomyces cerevisiae engineered to produce D-xylonate

Toivari, M. H., Ruohonen, L., Richard, P., Penttilä, M. & Wiebe, M. G., 1 Oct 2010, In : Applied Microbiology and Biotechnology. 88, 3, p. 751-760

Research output: Contribution to journalArticleScientificpeer-review

Xylose
Saccharomyces cerevisiae
NADP
Xylitol
Aldehyde Reductase
22 Citations (Scopus)

The 'true' l-xylulose reductase of filamentous fungi identified in Aspergillus niger

Mojzita, D., Vuoristo, K., Koivistoinen, O. M., Penttilä, M. & Richard, P., 1 Aug 2010, In : FEBS Letters. 584, 16, p. 3540-3544

Research output: Contribution to journalArticleScientificpeer-review

Xylulose
Aspergillus niger
Aspergillus
Fungi
Oxidoreductases