A cryotrap membrane introduction mass spectrometry system for analysis of volatile organic compounds in water at the low parts-per-trillion level

Maria Mendes, Regina Pimpim, Tapio Kotiaho, Marcos Eberlin (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

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Abstract

Detection of volatile organic compounds (VOCs) in aqueous solution at low parts-per-trillion (ppt) levels is accomplished using a very simple and efficient on-line preconcentration cryotrap membrane introduction mass spectrometry (CT-MIMS) system. The conventional MIMS probe is modified so that the membrane interface is placed about 15 cm away from the ion source. A U-shaped trap tube is then inserted between the membrane interface and the ion source. Cryotrapping is performed with liquid nitrogen for 15 min, followed by fast heating at ∼15 °C s-1, which thermally releases the condensed VOCs almost at once into the ion source region of a quadrupole mass spectrometer. By applying electron ionization and a selective ion monitoring scan mode, a very sharp and intense peak is obtained. The performance of the CT-MIMS system was compared with that of conventional MIMS, and after reaching the best conditions for the trapping and heating cycles, an improvement factor in signal intensity of about 100 was observed for a series of VOCs. The extraordinary sensitivity of CT-MIMS system allows VOCs to be detected at very low concentrations, detection limits being typically on the order of 10−20 ppt. The results also show excellent linearity and reproducibility for the system.
Original languageEnglish
Pages (from-to)3502-3506
Number of pages5
JournalAnalytical Chemistry
Volume68
Issue number19
DOIs
Publication statusPublished - 1996
MoE publication typeA1 Journal article-refereed

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Volatile Organic Compounds
Mass spectrometry
Membranes
Ion sources
Water
Heating
Mass spectrometers
Liquid nitrogen
Ionization
Ions
Electrons
Monitoring

Cite this

Mendes, Maria ; Pimpim, Regina ; Kotiaho, Tapio ; Eberlin, Marcos. / A cryotrap membrane introduction mass spectrometry system for analysis of volatile organic compounds in water at the low parts-per-trillion level. In: Analytical Chemistry. 1996 ; Vol. 68, No. 19. pp. 3502-3506.
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title = "A cryotrap membrane introduction mass spectrometry system for analysis of volatile organic compounds in water at the low parts-per-trillion level",
abstract = "Detection of volatile organic compounds (VOCs) in aqueous solution at low parts-per-trillion (ppt) levels is accomplished using a very simple and efficient on-line preconcentration cryotrap membrane introduction mass spectrometry (CT-MIMS) system. The conventional MIMS probe is modified so that the membrane interface is placed about 15 cm away from the ion source. A U-shaped trap tube is then inserted between the membrane interface and the ion source. Cryotrapping is performed with liquid nitrogen for 15 min, followed by fast heating at ∼15 °C s-1, which thermally releases the condensed VOCs almost at once into the ion source region of a quadrupole mass spectrometer. By applying electron ionization and a selective ion monitoring scan mode, a very sharp and intense peak is obtained. The performance of the CT-MIMS system was compared with that of conventional MIMS, and after reaching the best conditions for the trapping and heating cycles, an improvement factor in signal intensity of about 100 was observed for a series of VOCs. The extraordinary sensitivity of CT-MIMS system allows VOCs to be detected at very low concentrations, detection limits being typically on the order of 10−20 ppt. The results also show excellent linearity and reproducibility for the system.",
author = "Maria Mendes and Regina Pimpim and Tapio Kotiaho and Marcos Eberlin",
year = "1996",
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A cryotrap membrane introduction mass spectrometry system for analysis of volatile organic compounds in water at the low parts-per-trillion level. / Mendes, Maria; Pimpim, Regina; Kotiaho, Tapio; Eberlin, Marcos (Corresponding Author).

In: Analytical Chemistry, Vol. 68, No. 19, 1996, p. 3502-3506.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - A cryotrap membrane introduction mass spectrometry system for analysis of volatile organic compounds in water at the low parts-per-trillion level

AU - Mendes, Maria

AU - Pimpim, Regina

AU - Kotiaho, Tapio

AU - Eberlin, Marcos

PY - 1996

Y1 - 1996

N2 - Detection of volatile organic compounds (VOCs) in aqueous solution at low parts-per-trillion (ppt) levels is accomplished using a very simple and efficient on-line preconcentration cryotrap membrane introduction mass spectrometry (CT-MIMS) system. The conventional MIMS probe is modified so that the membrane interface is placed about 15 cm away from the ion source. A U-shaped trap tube is then inserted between the membrane interface and the ion source. Cryotrapping is performed with liquid nitrogen for 15 min, followed by fast heating at ∼15 °C s-1, which thermally releases the condensed VOCs almost at once into the ion source region of a quadrupole mass spectrometer. By applying electron ionization and a selective ion monitoring scan mode, a very sharp and intense peak is obtained. The performance of the CT-MIMS system was compared with that of conventional MIMS, and after reaching the best conditions for the trapping and heating cycles, an improvement factor in signal intensity of about 100 was observed for a series of VOCs. The extraordinary sensitivity of CT-MIMS system allows VOCs to be detected at very low concentrations, detection limits being typically on the order of 10−20 ppt. The results also show excellent linearity and reproducibility for the system.

AB - Detection of volatile organic compounds (VOCs) in aqueous solution at low parts-per-trillion (ppt) levels is accomplished using a very simple and efficient on-line preconcentration cryotrap membrane introduction mass spectrometry (CT-MIMS) system. The conventional MIMS probe is modified so that the membrane interface is placed about 15 cm away from the ion source. A U-shaped trap tube is then inserted between the membrane interface and the ion source. Cryotrapping is performed with liquid nitrogen for 15 min, followed by fast heating at ∼15 °C s-1, which thermally releases the condensed VOCs almost at once into the ion source region of a quadrupole mass spectrometer. By applying electron ionization and a selective ion monitoring scan mode, a very sharp and intense peak is obtained. The performance of the CT-MIMS system was compared with that of conventional MIMS, and after reaching the best conditions for the trapping and heating cycles, an improvement factor in signal intensity of about 100 was observed for a series of VOCs. The extraordinary sensitivity of CT-MIMS system allows VOCs to be detected at very low concentrations, detection limits being typically on the order of 10−20 ppt. The results also show excellent linearity and reproducibility for the system.

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