A low-aspect-ratio, roll-to-roll hot embossed inertial microfluidic sorter

X. Wang, C. Liedert, R. Liedert, I. Papautsky (Corresponding author)

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

1 Citation (Scopus)

Abstract

This work presents a low-aspect-ratio (LAR) inertial microfluidic design compatible with roll-to-roll (R2R) hot embossing for size-based cell or microparticle separation in a low-cost and disposable format. The device consists of two segments of LAR channels in which inertial lift forces are used to differentiate lateral positions based on size for separation downstream. Separation of 18µm and 15µm diameter particles was first demonstrated in a conventional PDMS device, and further validated in a thin-film device mass-produced by R2R embossing. The described LAR inertial microfluidic separator is ideally suited as a low-cost, disposable device for point-of-care sample preparation.
Original languageEnglish
Title of host publicationProceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Pages2447-2449
Publication statusPublished - 2014
MoE publication typeA4 Article in a conference publication
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 26 Oct 201430 Oct 2014
Conference number: 18

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Abbreviated titleMicroTAS 2014
CountryUnited States
CitySan Antonio
Period26/10/1430/10/14

Fingerprint

Microfluidics
Aspect ratio
Thin film devices
Separators
Costs

Keywords

  • inertial microfluidics
  • microfluidic sorting
  • roll-to-roll hot embossing

Cite this

Wang, X., Liedert, C., Liedert, R., & Papautsky, I. (2014). A low-aspect-ratio, roll-to-roll hot embossed inertial microfluidic sorter. In Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 2447-2449)
Wang, X. ; Liedert, C. ; Liedert, R. ; Papautsky, I. / A low-aspect-ratio, roll-to-roll hot embossed inertial microfluidic sorter. Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 2014. pp. 2447-2449
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Wang, X, Liedert, C, Liedert, R & Papautsky, I 2014, A low-aspect-ratio, roll-to-roll hot embossed inertial microfluidic sorter. in Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. pp. 2447-2449, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, United States, 26/10/14.

A low-aspect-ratio, roll-to-roll hot embossed inertial microfluidic sorter. / Wang, X.; Liedert, C.; Liedert, R.; Papautsky, I. (Corresponding author).

Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 2014. p. 2447-2449.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

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N2 - This work presents a low-aspect-ratio (LAR) inertial microfluidic design compatible with roll-to-roll (R2R) hot embossing for size-based cell or microparticle separation in a low-cost and disposable format. The device consists of two segments of LAR channels in which inertial lift forces are used to differentiate lateral positions based on size for separation downstream. Separation of 18µm and 15µm diameter particles was first demonstrated in a conventional PDMS device, and further validated in a thin-film device mass-produced by R2R embossing. The described LAR inertial microfluidic separator is ideally suited as a low-cost, disposable device for point-of-care sample preparation.

AB - This work presents a low-aspect-ratio (LAR) inertial microfluidic design compatible with roll-to-roll (R2R) hot embossing for size-based cell or microparticle separation in a low-cost and disposable format. The device consists of two segments of LAR channels in which inertial lift forces are used to differentiate lateral positions based on size for separation downstream. Separation of 18µm and 15µm diameter particles was first demonstrated in a conventional PDMS device, and further validated in a thin-film device mass-produced by R2R embossing. The described LAR inertial microfluidic separator is ideally suited as a low-cost, disposable device for point-of-care sample preparation.

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Wang X, Liedert C, Liedert R, Papautsky I. A low-aspect-ratio, roll-to-roll hot embossed inertial microfluidic sorter. In Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. 2014. p. 2447-2449