A MATLAB Toolbox for Classification and Visualization of Heterogenous Multi-Scale Human Data Using the Disease State Fingerprint Method

Luc Cluitmans, Jussi Mattila, Hilkka Runtti, Mark van Gils, Jyrki Lötjönen

    Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

    3 Citations (Scopus)

    Abstract

    As the amount of data acquired from humans is constantly increasing, efficient tools are needed for extracting relevant information from this data. This paper presents a Matlab implementation of a method to classify and visually explore (highly) multi-variate patient data. The method uses the so-called Disease State Index (DSI) which measures the fit of a test subject's data to two classes present in the data (e.g. 'controls' and 'positives'). DSI values of the different variables measured from a patient can be combined and visualized in a tree-like form using the Disease State Fingerprint (DSF) method. This allows a researcher to explore and understand the relevance of the different variables in classification problems. Moreover, the method is robust with respect to missing data. After giving an introduction to the DSF and DSI methods, the paper describes the steps required to use the methods and presents a MATLAB toolbox to perform these steps. To demonstrate the methods' versatility, the paper illustrates the usage of the toolbox in a few different contexts in which personal health data is to be classified. With this implementation, a powerful and flexible tool is made available to the biomedical research community.
    Original languageEnglish
    Title of host publicationpHealth 2013
    Subtitle of host publicationProceedings of the 10th International Conference on Wearable Micro and Nano Technologies for Personalized Health
    Place of PublicationAmsterdam
    PublisherIOS Press
    Pages77-82
    ISBN (Print)978-1-61499-267-7 , 978-1-61499-268-4
    DOIs
    Publication statusPublished - 2013
    MoE publication typeNot Eligible
    Event10th International Conference on Wearable Micro and Nano Technologies for Personalized Health, pHealth 2013 - Tallinn, Estonia
    Duration: 26 Jun 201328 Jun 2013

    Publication series

    SeriesStudies in Health Technology and Informatics
    Volume189
    ISSN0926-9630

    Conference

    Conference10th International Conference on Wearable Micro and Nano Technologies for Personalized Health, pHealth 2013
    Abbreviated titlepHealth 2013
    Country/TerritoryEstonia
    CityTallinn
    Period26/06/1328/06/13

    Keywords

    • decision support
    • multi-variate classification
    • data visualization
    • MATLAB

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