A microfluidic droplet system for ultra-monodisperse droplet generation: A universal approach

Ali Kalantarifard, Elnaz Alizadeh-Haghighi, Caglar Elbuken (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)


Despite the importance of droplet monodispersity, a universal methodology for high monodispersity droplet generation does not exist yet. We have recently demonstrated that unlike the conventional method of droplet generation, applying an identical pressure from a single source makes the microfluidic droplet system immune to the external fluctuations that originate from the imperfection of the flow source. In this work, we show that our method is universal and applicable to other common microfluidic devices and flow sources. We applied this method to flow-focusing and coflow devices that are commonly used for high-frequency microdroplet generation. In addition to the pressure pump, we used a syringe pump to show that our method is applicable to flow rate controllable systems as well. We compared the monodispersity of droplets formed by the conventional methods and the novel method explained in this work.

Original languageEnglish
Article number117947
JournalChemical Engineering Science
Publication statusPublished - 2 Nov 2022
MoE publication typeA1 Journal article-refereed


  • Coflow
  • Flow-focusing
  • Microdroplets
  • Microfluidics
  • Monodispersity
  • Two phase flow


Dive into the research topics of 'A microfluidic droplet system for ultra-monodisperse droplet generation: A universal approach'. Together they form a unique fingerprint.

Cite this