Acute toxic effects of a novel cyanobacterial toxin on the crustaceans Artemia salina and Daphnia pulex

Marko Reinikainen, Jari Kiviranta, Veikko Ulvi, Marja-Leena Niku-Paavola

Research output: Contribution to journalArticleScientificpeer-review

22 Citations (Scopus)

Abstract

A strain of the cyanobacterium Oscillatoria agardhii non-toxic to mice was toxic to the crustaceans Daphnia pulex and Artemia salina.
The 48 h EC(50)-value of a water extract to D. pulex corresponded to 0.26 mg/ml of freeze-dried cyanobacteria, and the 48 h EC(50)-value of a semi-purified, freeze-dried, water extract was 0.06 mg/ml. Whole cells were also toxic, but no clear dose-effect relationship could be established, probably because the feeding of the animals was inhibited.
The toxic effect on D. pulex was reversible. Further purification of the toxin was achieved using gel filtration. A subsequent testing of the toxicity of the gel filtration fractions, using both species of crustaceans, suggests that a single compound caused the observed toxicity.
The molecular weight of this toxin was around 2,000, as detected during gel filtration.
Original languageEnglish
Pages (from-to)61-69
JournalArchiv für Hydrobiologie
Volume133
Issue number1
Publication statusPublished - 1995
MoE publication typeNot Eligible

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cyanobacterial toxins
Daphnia pulex
Artemia salina
toxin
crustacean
gel
Crustacea
gels
Cyanobacteria
cyanobacterium
toxins
Oscillatoria agardhii
toxicity
animal feeding
extracts
toxicity testing
purification
water
molecular weight
animal

Cite this

Reinikainen, M., Kiviranta, J., Ulvi, V., & Niku-Paavola, M-L. (1995). Acute toxic effects of a novel cyanobacterial toxin on the crustaceans Artemia salina and Daphnia pulex. Archiv für Hydrobiologie, 133(1), 61-69.
Reinikainen, Marko ; Kiviranta, Jari ; Ulvi, Veikko ; Niku-Paavola, Marja-Leena. / Acute toxic effects of a novel cyanobacterial toxin on the crustaceans Artemia salina and Daphnia pulex. In: Archiv für Hydrobiologie. 1995 ; Vol. 133, No. 1. pp. 61-69.
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abstract = "A strain of the cyanobacterium Oscillatoria agardhii non-toxic to mice was toxic to the crustaceans Daphnia pulex and Artemia salina. The 48 h EC(50)-value of a water extract to D. pulex corresponded to 0.26 mg/ml of freeze-dried cyanobacteria, and the 48 h EC(50)-value of a semi-purified, freeze-dried, water extract was 0.06 mg/ml. Whole cells were also toxic, but no clear dose-effect relationship could be established, probably because the feeding of the animals was inhibited. The toxic effect on D. pulex was reversible. Further purification of the toxin was achieved using gel filtration. A subsequent testing of the toxicity of the gel filtration fractions, using both species of crustaceans, suggests that a single compound caused the observed toxicity. The molecular weight of this toxin was around 2,000, as detected during gel filtration.",
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Reinikainen, M, Kiviranta, J, Ulvi, V & Niku-Paavola, M-L 1995, 'Acute toxic effects of a novel cyanobacterial toxin on the crustaceans Artemia salina and Daphnia pulex', Archiv für Hydrobiologie, vol. 133, no. 1, pp. 61-69.

Acute toxic effects of a novel cyanobacterial toxin on the crustaceans Artemia salina and Daphnia pulex. / Reinikainen, Marko; Kiviranta, Jari; Ulvi, Veikko; Niku-Paavola, Marja-Leena.

In: Archiv für Hydrobiologie, Vol. 133, No. 1, 1995, p. 61-69.

Research output: Contribution to journalArticleScientificpeer-review

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T1 - Acute toxic effects of a novel cyanobacterial toxin on the crustaceans Artemia salina and Daphnia pulex

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AB - A strain of the cyanobacterium Oscillatoria agardhii non-toxic to mice was toxic to the crustaceans Daphnia pulex and Artemia salina. The 48 h EC(50)-value of a water extract to D. pulex corresponded to 0.26 mg/ml of freeze-dried cyanobacteria, and the 48 h EC(50)-value of a semi-purified, freeze-dried, water extract was 0.06 mg/ml. Whole cells were also toxic, but no clear dose-effect relationship could be established, probably because the feeding of the animals was inhibited. The toxic effect on D. pulex was reversible. Further purification of the toxin was achieved using gel filtration. A subsequent testing of the toxicity of the gel filtration fractions, using both species of crustaceans, suggests that a single compound caused the observed toxicity. The molecular weight of this toxin was around 2,000, as detected during gel filtration.

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JO - Fundamental and Applied Limnology

JF - Fundamental and Applied Limnology

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