An integrated approach to bioprocess recipe design

Juho Rousu (Corresponding Author), Robert Aarts

Research output: Contribution to journalArticleScientificpeer-review

4 Citations (Scopus)

Abstract

Biotechnical and food process industries have a need for tools that support the implementation of modern manufacturing practice. Flexible production strategies and total quality management require efficient design of the process recipes. This paper presents the approach used in Sophist, an adaptive recipe planning system. The system integrates case-based reasoning and a semi-qualitative process model for the design and optimisation of bioprocess recipes. In particular, we introduce a novel revision selection algorithm that improve the system's adaptivity. The behavior of the planner is exemplified by a batch fermentation planning experiment.
Original languageEnglish
Pages (from-to)363-373
Number of pages11
JournalIntegrated Computer-Aided Engineering
Volume8
Issue number4
DOIs
Publication statusPublished - 2001
MoE publication typeA1 Journal article-refereed

Fingerprint

Planning
Total quality management
Case based reasoning
Fermentation
Process Industry
Quality Management
Case-based Reasoning
Adaptivity
Tool Support
Process Model
Batch
Manufacturing
Integrate
Industry
Optimization
Experiments
Experiment
Design
Strategy

Cite this

Rousu, Juho ; Aarts, Robert. / An integrated approach to bioprocess recipe design. In: Integrated Computer-Aided Engineering. 2001 ; Vol. 8, No. 4. pp. 363-373.
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An integrated approach to bioprocess recipe design. / Rousu, Juho (Corresponding Author); Aarts, Robert.

In: Integrated Computer-Aided Engineering, Vol. 8, No. 4, 2001, p. 363-373.

Research output: Contribution to journalArticleScientificpeer-review

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