Antidesmone, a novel antitrypanosomal alkaloid

G. Bringmann (Corresponding Author), J. Schlauer, Heiko Rischer, M. Wohlfarth, R. Haller, S. Bär, R. Brun

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)

Abstract

Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.
Original languageEnglish
Pages (from-to)47-48
Number of pages2
JournalPharmaceutical and pharmacological letters
Volume11
Issue number2
Publication statusPublished - 2001
MoE publication typeA1 Journal article-refereed

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Alkaloids
Quinolones
antidesmone
Parasites

Cite this

Bringmann, G., Schlauer, J., Rischer, H., Wohlfarth, M., Haller, R., Bär, S., & Brun, R. (2001). Antidesmone, a novel antitrypanosomal alkaloid. Pharmaceutical and pharmacological letters, 11(2), 47-48.
Bringmann, G. ; Schlauer, J. ; Rischer, Heiko ; Wohlfarth, M. ; Haller, R. ; Bär, S. ; Brun, R. / Antidesmone, a novel antitrypanosomal alkaloid. In: Pharmaceutical and pharmacological letters. 2001 ; Vol. 11, No. 2. pp. 47-48.
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Bringmann, G, Schlauer, J, Rischer, H, Wohlfarth, M, Haller, R, Bär, S & Brun, R 2001, 'Antidesmone, a novel antitrypanosomal alkaloid', Pharmaceutical and pharmacological letters, vol. 11, no. 2, pp. 47-48.

Antidesmone, a novel antitrypanosomal alkaloid. / Bringmann, G. (Corresponding Author); Schlauer, J.; Rischer, Heiko; Wohlfarth, M.; Haller, R.; Bär, S.; Brun, R.

In: Pharmaceutical and pharmacological letters, Vol. 11, No. 2, 2001, p. 47-48.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Antidesmone, a novel antitrypanosomal alkaloid

AU - Bringmann, G.

AU - Schlauer, J.

AU - Rischer, Heiko

AU - Wohlfarth, M.

AU - Haller, R.

AU - Bär, S.

AU - Brun, R.

PY - 2001

Y1 - 2001

N2 - Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.

AB - Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.

M3 - Article

VL - 11

SP - 47

EP - 48

JO - Pharmaceutical and pharmacological letters

JF - Pharmaceutical and pharmacological letters

SN - 0939-9488

IS - 2

ER -

Bringmann G, Schlauer J, Rischer H, Wohlfarth M, Haller R, Bär S et al. Antidesmone, a novel antitrypanosomal alkaloid. Pharmaceutical and pharmacological letters. 2001;11(2):47-48.