Antidesmone, a novel antitrypanosomal alkaloid

G. Bringmann (Corresponding Author), J. Schlauer, Heiko Rischer, M. Wohlfarth, R. Haller, S. Bär, R. Brun

    Research output: Contribution to journalArticleScientificpeer-review

    7 Citations (Scopus)

    Abstract

    Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.
    Original languageEnglish
    Pages (from-to)47-48
    Number of pages2
    JournalPharmaceutical and pharmacological letters
    Volume11
    Issue number2
    Publication statusPublished - 2001
    MoE publication typeA1 Journal article-refereed

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