Antidesmone, a novel antitrypanosomal alkaloid

G. Bringmann (Corresponding Author), J. Schlauer, Heiko Rischer, M. Wohlfarth, R. Haller, S. Bär, R. Brun

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Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.
Original languageEnglish
Pages (from-to)47-48
Number of pages2
JournalPharmaceutical and pharmacological letters
Issue number2
Publication statusPublished - 2001
MoE publication typeA1 Journal article-refereed


Cite this

Bringmann, G., Schlauer, J., Rischer, H., Wohlfarth, M., Haller, R., Bär, S., & Brun, R. (2001). Antidesmone, a novel antitrypanosomal alkaloid. Pharmaceutical and pharmacological letters, 11(2), 47-48.