Antidesmone, a novel antitrypanosomal alkaloid

G. Bringmann; J. Schlauer; Heiko Rischer; M. Wohlfarth; R. Haller; S. Bär; R. Brun

Antidesmone, a novel antitrypanosomal alkaloid

G. Bringmann (Corresponding Author), J. Schlauer, Heiko Rischer, M. Wohlfarth, R. Haller, S. Bär, R. Brun

Research output: Contribution to journal › Article › Scientific › peer-review

Abstract

Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.

Original language	English
Pages (from-to)	47-48
Number of pages	2
Journal	Pharmaceutical and pharmacological letters
Volume	11
Issue number	2
Publication status	Published - 2001
MoE publication type	A1 Journal article-refereed

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title = "Antidesmone, a novel antitrypanosomal alkaloid",

abstract = "Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.",

author = "G. Bringmann and J. Schlauer and Heiko Rischer and M. Wohlfarth and R. Haller and S. B{\"a}r and R. Brun",

year = "2001",

language = "English",

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TY - JOUR

T1 - Antidesmone, a novel antitrypanosomal alkaloid

AU - Bringmann, G.

AU - Schlauer, J.

AU - Rischer, Heiko

AU - Wohlfarth, M.

AU - Haller, R.

AU - Bär, S.

AU - Brun, R.

PY - 2001

Y1 - 2001

N2 - Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.

AB - Antidesmone, a novel acetogenic quinolone alkaloid from the African shrub Antidesma membranaceum, has been found to exhibit potent antitrypanosomal activity against Trypanasoma cruzi, the pathogenic agent of Chagas disease. The activity seems to be highly selective, being much larger than that towards other protozoan parasites causing tropical diseases.

M3 - Article

SN - 0939-9488

VL - 11

SP - 47

EP - 48

JO - Pharmaceutical and pharmacological letters

JF - Pharmaceutical and pharmacological letters

IS - 2

ER -

Antidesmone, a novel antitrypanosomal alkaloid

Abstract

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