Abstract
Aims: To investigate the antimicrobial properties of phenolic compounds present in Finnish berries against probiotic bacteria and other intestinal bacteria, including pathogenic species.
Methods and Results: Antimicrobial activity of pure phenolic compounds representing flavonoids and phenolic acids, and eight extracts from common Finnish berries, was measured against selected Gram‐positive and Gram‐negative bacterial species, including probiotic bacteria and the intestinal pathogen Salmonella. Antimicrobial activity was screened by an agar diffusion method and bacterial growth was measured in liquid culture as a more accurate assay. Myricetin inhibited the growth of all lactic acid bacteria derived from the human gastrointestinal tract flora but it did not affect the Salmonella strain. In general, berry extracts inhibited the growth of Gram‐negative but not Gram‐positive bacteria. These variations may reflect differences in cell surface structures between Gram‐negative and Gram‐positive bacteria. Cloudberry, raspberry and strawberry extracts were strong inhibitors of Salmonella. Sea buckthorn berry and blackcurrant showed the least activity against Gram‐negative bacteria.
Conclusions: Different bacterial species exhibit different sensitivities towards phenolics.
Significance and Impact of the Study: These properties can be utilized in functional food development and in food preservative purposes.
Methods and Results: Antimicrobial activity of pure phenolic compounds representing flavonoids and phenolic acids, and eight extracts from common Finnish berries, was measured against selected Gram‐positive and Gram‐negative bacterial species, including probiotic bacteria and the intestinal pathogen Salmonella. Antimicrobial activity was screened by an agar diffusion method and bacterial growth was measured in liquid culture as a more accurate assay. Myricetin inhibited the growth of all lactic acid bacteria derived from the human gastrointestinal tract flora but it did not affect the Salmonella strain. In general, berry extracts inhibited the growth of Gram‐negative but not Gram‐positive bacteria. These variations may reflect differences in cell surface structures between Gram‐negative and Gram‐positive bacteria. Cloudberry, raspberry and strawberry extracts were strong inhibitors of Salmonella. Sea buckthorn berry and blackcurrant showed the least activity against Gram‐negative bacteria.
Conclusions: Different bacterial species exhibit different sensitivities towards phenolics.
Significance and Impact of the Study: These properties can be utilized in functional food development and in food preservative purposes.
| Original language | English |
|---|---|
| Pages (from-to) | 494-507 |
| Number of pages | 14 |
| Journal | Journal of Applied Microbiology |
| Volume | 90 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2001 |
| MoE publication type | A1 Journal article-refereed |
Keywords
- antimicrobial activity
- antimicrobial properties
- berries
- phenolic compounds
- phenolics
- human health
