Application of cryobiotechnologies for development of lyophilized polyenzyme complexes

M. Doneva, I. Nacheva, P. Metodieva, Yancho Todorov, D. Miteva, L. Georgieva, Tsv. Tsvetkov

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)


Good nutrition is key factor for human health. Conditions of secondary insufficiency of the gastric gland and a decreased production of digestive enzymes lead to changes in the gastric-intestinal metabolism, which imposes the intake polyenzyme products as food supplement. The created on the basis of freeze-drying complex polyenzyme product with its composition, containing the main groups digestive enzymes (chymosin, α – amylase, bromelain, lipase), incorporated in a hydrocolloid matrix and in combination with plant biologically active components is appropriate for prophylaxis in cases of gastric-intestinal tract discomfort and disturbed digestion. The obtained product was qualified by organoleptic, biochemical, physical-chemical and microbiological characteristics. The retaining of the catalytic activity of the enzyme substances and the chemical composition of the incorporated biologically active substances has been established.

Original languageEnglish
Pages (from-to)1401-1405
Number of pages5
JournalBulgarian Journal of Agricultural Science
Issue number6
Publication statusPublished - 1 Jan 2014
MoE publication typeA1 Journal article-refereed


  • Digestion
  • Freeze-drying
  • Polyenzyme product


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