Assembly of citrate gold nanoparticles on hydrophilic monolayers

Inger Vikholm-Lundin (Corresponding Author), Emil Rosqvist, Petri Ihalainen, Tony Munter, Anni Honkimaa, Varpu Marjomäki, Willem M. Albers, Jouko Peltonen

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)

Abstract

Self-assembled monolayers (SAMs) as model surfaces were linked onto planar gold films thorough lipoic acid or disulfide groups. The molecules used were polyethylene glycol (EG-S-S), N-[tris-(hydroxymethyl)methyl]acrylamide polymers with and without lipoic acid (Lipa-pTHMMAA and pTHMMAA) and a lipoic acid triazine derivative (Lipa-MF). All the layers, but Lipa-MF with a primary amino group were hydroxyl terminated. The layers were characterized by contact angle measurements and atomic force microscopy, AFM. Citrate stabilized nanoparticles, AuNPs in water and phosphate buffer were allowed to assemble on the layers for 10 min and the binding was followed in real-time with surface plasmon resonance, SPR. The SPR resonance curves were observed to shift to higher angles and become increasingly damped, while also the peaks strongly broaden when large nanoparticles assembled on the surface. Both the angular shift and the damping of the curve was largest for nanoparticles assembling on the EG-S-S monolayer. High amounts of particles were also assembled on the pTHMMAA layer without the lipoic acid group, but the damping of the curve was considerably lower with a more even distribution of the particles. Topographical images confirmed that the highest number of particles were assembled on the polyethylene glycol monolayer. By increasing the interaction time more particles could be assembled on the surface.
Original languageEnglish
Pages (from-to)519-529
JournalApplied Surface Science
Volume378
DOIs
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed

Fingerprint

Thioctic Acid
Citric Acid
Gold
Monolayers
Nanoparticles
Acids
Polyethylene glycols
Damping
Triazines
Acrylamide
Surface plasmon resonance
Self assembled monolayers
Angle measurement
Disulfides
Hydroxyl Radical
Contact angle
Atomic force microscopy
Buffers
Polymers
Phosphates

Keywords

  • Hydrophilic monolayers
  • Gold nanoparticles
  • Surface plasmon resonance (SPR)
  • Atomic force microscopy (AFM)
  • Contact angle

Cite this

Vikholm-Lundin, I., Rosqvist, E., Ihalainen, P., Munter, T., Honkimaa, A., Marjomäki, V., ... Peltonen, J. (2016). Assembly of citrate gold nanoparticles on hydrophilic monolayers. Applied Surface Science, 378, 519-529. https://doi.org/10.1016/j.apsusc.2016.03.213
Vikholm-Lundin, Inger ; Rosqvist, Emil ; Ihalainen, Petri ; Munter, Tony ; Honkimaa, Anni ; Marjomäki, Varpu ; Albers, Willem M. ; Peltonen, Jouko. / Assembly of citrate gold nanoparticles on hydrophilic monolayers. In: Applied Surface Science. 2016 ; Vol. 378. pp. 519-529.
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Vikholm-Lundin, I, Rosqvist, E, Ihalainen, P, Munter, T, Honkimaa, A, Marjomäki, V, Albers, WM & Peltonen, J 2016, 'Assembly of citrate gold nanoparticles on hydrophilic monolayers', Applied Surface Science, vol. 378, pp. 519-529. https://doi.org/10.1016/j.apsusc.2016.03.213

Assembly of citrate gold nanoparticles on hydrophilic monolayers. / Vikholm-Lundin, Inger (Corresponding Author); Rosqvist, Emil; Ihalainen, Petri; Munter, Tony; Honkimaa, Anni; Marjomäki, Varpu; Albers, Willem M.; Peltonen, Jouko.

In: Applied Surface Science, Vol. 378, 2016, p. 519-529.

Research output: Contribution to journalArticleScientificpeer-review

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T1 - Assembly of citrate gold nanoparticles on hydrophilic monolayers

AU - Vikholm-Lundin, Inger

AU - Rosqvist, Emil

AU - Ihalainen, Petri

AU - Munter, Tony

AU - Honkimaa, Anni

AU - Marjomäki, Varpu

AU - Albers, Willem M.

AU - Peltonen, Jouko

PY - 2016

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N2 - Self-assembled monolayers (SAMs) as model surfaces were linked onto planar gold films thorough lipoic acid or disulfide groups. The molecules used were polyethylene glycol (EG-S-S), N-[tris-(hydroxymethyl)methyl]acrylamide polymers with and without lipoic acid (Lipa-pTHMMAA and pTHMMAA) and a lipoic acid triazine derivative (Lipa-MF). All the layers, but Lipa-MF with a primary amino group were hydroxyl terminated. The layers were characterized by contact angle measurements and atomic force microscopy, AFM. Citrate stabilized nanoparticles, AuNPs in water and phosphate buffer were allowed to assemble on the layers for 10 min and the binding was followed in real-time with surface plasmon resonance, SPR. The SPR resonance curves were observed to shift to higher angles and become increasingly damped, while also the peaks strongly broaden when large nanoparticles assembled on the surface. Both the angular shift and the damping of the curve was largest for nanoparticles assembling on the EG-S-S monolayer. High amounts of particles were also assembled on the pTHMMAA layer without the lipoic acid group, but the damping of the curve was considerably lower with a more even distribution of the particles. Topographical images confirmed that the highest number of particles were assembled on the polyethylene glycol monolayer. By increasing the interaction time more particles could be assembled on the surface.

AB - Self-assembled monolayers (SAMs) as model surfaces were linked onto planar gold films thorough lipoic acid or disulfide groups. The molecules used were polyethylene glycol (EG-S-S), N-[tris-(hydroxymethyl)methyl]acrylamide polymers with and without lipoic acid (Lipa-pTHMMAA and pTHMMAA) and a lipoic acid triazine derivative (Lipa-MF). All the layers, but Lipa-MF with a primary amino group were hydroxyl terminated. The layers were characterized by contact angle measurements and atomic force microscopy, AFM. Citrate stabilized nanoparticles, AuNPs in water and phosphate buffer were allowed to assemble on the layers for 10 min and the binding was followed in real-time with surface plasmon resonance, SPR. The SPR resonance curves were observed to shift to higher angles and become increasingly damped, while also the peaks strongly broaden when large nanoparticles assembled on the surface. Both the angular shift and the damping of the curve was largest for nanoparticles assembling on the EG-S-S monolayer. High amounts of particles were also assembled on the pTHMMAA layer without the lipoic acid group, but the damping of the curve was considerably lower with a more even distribution of the particles. Topographical images confirmed that the highest number of particles were assembled on the polyethylene glycol monolayer. By increasing the interaction time more particles could be assembled on the surface.

KW - Hydrophilic monolayers

KW - Gold nanoparticles

KW - Surface plasmon resonance (SPR)

KW - Atomic force microscopy (AFM)

KW - Contact angle

U2 - 10.1016/j.apsusc.2016.03.213

DO - 10.1016/j.apsusc.2016.03.213

M3 - Article

VL - 378

SP - 519

EP - 529

JO - Applied Surface Science

JF - Applied Surface Science

SN - 0169-4332

ER -

Vikholm-Lundin I, Rosqvist E, Ihalainen P, Munter T, Honkimaa A, Marjomäki V et al. Assembly of citrate gold nanoparticles on hydrophilic monolayers. Applied Surface Science. 2016;378:519-529. https://doi.org/10.1016/j.apsusc.2016.03.213