Abstract
A hard nut to crack: The asymmetric intermolecular Markovnikov addition of simple amines to unactivated alkenes can be achieved utilizing binaphtholate rare-earth-metal catalysts with up to 61% ee and 73% de in the case where R 2 contains a stereogenic center.
| Original language | English |
|---|---|
| Pages (from-to) | 8984-8987 |
| Number of pages | 4 |
| Journal | Angewandte Chemie: International Edition |
| Volume | 49 |
| Issue number | 47 |
| DOIs | |
| Publication status | Published - 15 Nov 2010 |
| MoE publication type | A1 Journal article-refereed |
Keywords
- alkenes
- amines
- enantioselectivity
- intermolecular hydroamination
- rare-earth metals