Projects per year
Abstract
Flexible and easy-to-use microfluidic systems are suitable options for point-of-care diagnostics. Here, we investigate liquid transport in fluidic channels produced by stencil printing on flexible substrates as a reproducible and scalable option for diagnostics and paper-based sensing. Optimal printability and flow profiles were obtained by combining minerals with cellulose fibrils of two different characteristic dimensions, in the nano- and microscales, forming channels with ideal wettability. Biomolecular ligands were easily added by inkjet printing on the channels, which were tested for the simultaneous detection of glucose and proteins. Accurate determination of clinically relevant concentrations was possible from linear calibration, confirming the potential of the introduced paper-based diagnostics. The results indicate the promise of simple but reliable fluidic channels for drug and chemical analyses, chromatographic separation, and quality control.
Original language | English |
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Pages (from-to) | 5536-5546 |
Journal | ACS Applied Polymer Materials |
Volume | 3 |
Issue number | 11 |
Early online date | 4 Oct 2021 |
Publication status | Published - 12 Nov 2021 |
MoE publication type | A1 Journal article-refereed |
Keywords
- fluidic channel
- liquid wicking materials
- multisensing assay
- paper-based microfluidics
- stencil printing
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Dive into the research topics of 'Bicomponent Cellulose Fibrils and Minerals Afford Wicking Channels Stencil-Printed on Paper for Rapid and Reliable Fluidic Platforms'. Together they form a unique fingerprint.Projects
- 1 Finished
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INNPAPER: Innovative and Smart Printed Electronics based on Multifunctionalized Paper: from Smart Labelling to Point of Care Bioplatforms
Khakalo, A. (Manager), Tammelin, T. (Owner), Orelma, H. (Participant), Solin, K. (Participant) & Mäkelä, T. (Participant)
1/02/18 → 31/12/21
Project: EU project