Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 8 - 18 |
| Number of pages | 11 |
| Journal | Applied Microbiology and Biotechnology |
| Volume | 67 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2005 |
| MoE publication type | A1 Journal article-refereed |
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Keywords
- berries
- cranberry
- cloudberry
- raspberry
- strawberry
- bilberry
- antimicrobial effects
- antimicrobial agents
- Salmonella
- Staphylococcus
- phenolic polymers
- ellagitannins
Cite this
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Bioactive berry compounds : Novel tools against human pathogens. / Puupponen-Pimiä, Riitta (Corresponding Author); Nohynek, Liisa; Alakomi, Hanna-Leena; Oksman-Caldentey, Kirsi-Marja.
In: Applied Microbiology and Biotechnology, Vol. 67, No. 1, 2005, p. 8 - 18.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Bioactive berry compounds
T2 - Novel tools against human pathogens
AU - Puupponen-Pimiä, Riitta
AU - Nohynek, Liisa
AU - Alakomi, Hanna-Leena
AU - Oksman-Caldentey, Kirsi-Marja
PY - 2005
Y1 - 2005
N2 - Berry fruits are rich sources of bioactive compounds, such as phenolics and organic acids, which have antimicrobial activities against human pathogens. Among different berries and berry phenolics, cranberry, cloudberry, raspberry, strawberry and bilberry especially possess clear antimicrobial effects against, e.g. Salmonella and Staphylococcus. Complex phenolic polymers, like ellagitannins, are strong antibacterial agents present in cloudberry and raspberry. Several mechanisms of action in the growth inhibition of bacteria are involved, such as destabilisation of cytoplasmic membrane, permeabilisation of plasma membrane, inhibition of extracellular microbial enzymes, direct actions on microbial metabolism and deprivation of the substrates required for microbial growth. Antimicrobial activity of berries may also be related to antiadherence of bacteria to epithelial cells, which is a prerequisite for colonisation and infection of many pathogens. Antimicrobial berry compounds may have important applications in the future as natural antimicrobial agents for food industry as well as for medicine. Some of the novel approaches are discussed.
AB - Berry fruits are rich sources of bioactive compounds, such as phenolics and organic acids, which have antimicrobial activities against human pathogens. Among different berries and berry phenolics, cranberry, cloudberry, raspberry, strawberry and bilberry especially possess clear antimicrobial effects against, e.g. Salmonella and Staphylococcus. Complex phenolic polymers, like ellagitannins, are strong antibacterial agents present in cloudberry and raspberry. Several mechanisms of action in the growth inhibition of bacteria are involved, such as destabilisation of cytoplasmic membrane, permeabilisation of plasma membrane, inhibition of extracellular microbial enzymes, direct actions on microbial metabolism and deprivation of the substrates required for microbial growth. Antimicrobial activity of berries may also be related to antiadherence of bacteria to epithelial cells, which is a prerequisite for colonisation and infection of many pathogens. Antimicrobial berry compounds may have important applications in the future as natural antimicrobial agents for food industry as well as for medicine. Some of the novel approaches are discussed.
KW - berries
KW - cranberry
KW - cloudberry
KW - raspberry
KW - strawberry
KW - bilberry
KW - antimicrobial effects
KW - antimicrobial agents
KW - Salmonella
KW - Staphylococcus
KW - phenolic polymers
KW - ellagitannins
U2 - 10.1007/s00253-004-1817-x
DO - 10.1007/s00253-004-1817-x
M3 - Article
VL - 67
SP - 8
EP - 18
JO - Applied Microbiology and Biotechnology
JF - Applied Microbiology and Biotechnology
SN - 0175-7598
IS - 1
ER -