Bioactivities of fish protein hydrolysates from defatted salmon backbones

Rasa Slizyte (Corresponding Author), Katariina Rommi, Revilija Mozuraityte, Peter Eck, Kathrine FIve, Turid Rustad

Research output: Contribution to journalArticleScientificpeer-review

20 Citations (Scopus)

Abstract

Bioactivities of bulk fish protein hydrolysates (FPH) from defatted salmon backbones obtained with eight different commercial enzymes and their combinations were tested. All FPH showed antioxidative activity in vitro. DPPH scavenging activity increased, while iron chelating ability decreased with increasing time of hydrolysis. All FPH showed ACE inhibiting effect which depended on type of enzyme and increased with time of hydrolysis. The highest effect was found for FPH produced with Trypsin. Bromelain + Papain hydrolysates reduced the uptake of radiolabelled glucose into CaCo-2 cells, a model of human enterocytes, indicating a potential antidiabetic effect of FPH. FPH obtained by Trypsin, Bromelain + Papain and Protamex showed the highest ACE inhibitory, cellular glucose transporter (GLUT/SGLT) inhibitory and in vitro antioxidative activities, respectively. Correlation was observed between the measured bioactivities, degree of hydrolysis and molecular weight profiles, supporting prolonged hydrolysis to obtain high bioactivities.
Original languageEnglish
Pages (from-to)99-109
JournalBiotechnology Reports
Volume11
DOIs
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed

Fingerprint

Fish Proteins
Protein Hydrolysates
Salmon
Hydrolysis
Bromelains
Papain
Trypsin
Caco-2 Cells
Facilitative Glucose Transport Proteins
Enterocytes
Enzymes
Hypoglycemic Agents
Iron
Molecular Weight
Glucose

Keywords

  • ACE-inhibition
  • antioxidant
  • fish protein hydrolysates
  • clucose transport inhibition
  • salmon backbones

Cite this

Slizyte, R., Rommi, K., Mozuraityte, R., Eck, P., FIve, K., & Rustad, T. (2016). Bioactivities of fish protein hydrolysates from defatted salmon backbones. Biotechnology Reports, 11, 99-109. https://doi.org/10.1016/j.btre.2016.08.003
Slizyte, Rasa ; Rommi, Katariina ; Mozuraityte, Revilija ; Eck, Peter ; FIve, Kathrine ; Rustad, Turid. / Bioactivities of fish protein hydrolysates from defatted salmon backbones. In: Biotechnology Reports. 2016 ; Vol. 11. pp. 99-109.
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Slizyte, R, Rommi, K, Mozuraityte, R, Eck, P, FIve, K & Rustad, T 2016, 'Bioactivities of fish protein hydrolysates from defatted salmon backbones', Biotechnology Reports, vol. 11, pp. 99-109. https://doi.org/10.1016/j.btre.2016.08.003

Bioactivities of fish protein hydrolysates from defatted salmon backbones. / Slizyte, Rasa (Corresponding Author); Rommi, Katariina; Mozuraityte, Revilija; Eck, Peter; FIve, Kathrine; Rustad, Turid.

In: Biotechnology Reports, Vol. 11, 2016, p. 99-109.

Research output: Contribution to journalArticleScientificpeer-review

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AU - Slizyte, Rasa

AU - Rommi, Katariina

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AU - FIve, Kathrine

AU - Rustad, Turid

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