Biodegradable and bioactive hybrid organic-inorganic PEG-siloxane fibers. Preparation and characterization

B. Granqvist, A. Helminen, M. Vehviläinen, V. Ääritalo, J. Seppälä, Mika Lindén (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)

Abstract

A mixture of triethoxysilanefunctionalized poly(ethylene glycol), f-PEG, and tetraethoxysilane, TEOS, was used as precursors in the preparation of continuous hybrid f-PEG-siloxane sol-gel derived fibers. The fibers were spun by extrusion through a spinneret. The thus prepared fibers had a diameter of 20-50 μm. 29Si-CPMAS NMR measurements confirmed that the functionalized PEG is incorporated into the siloxane network through covalent bonds. The hybrid fiber elasticity was much higher than that of fibers spun from sols with TEOS as the only source for silica. However, the f-PEG chain length plays a crucial role for the spinnability of the sol, since, as a result of bridging flocculation, macroscopic phase separation occurred readily with increasing chain length of the f-PEG. The fibers were shown to be effective substrates for the nucleation and growth of bone-like hydroxyapatite.

Original languageEnglish
Pages (from-to)495-501
Number of pages7
JournalColloid and Polymer Science
Volume282
Issue number5
DOIs
Publication statusPublished - 1 Mar 2004
MoE publication typeA1 Journal article-refereed

Keywords

  • Bioactivce
  • Biodegradable
  • Fiber
  • Hybrid
  • Silica

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