Bioreactor studies on hairy root cultures of Catharanthus roseus

Comparison of three bioreactor types

Anna-Maria Nuutila, Leena Toivonen, Veli Kauppinen

    Research output: Contribution to journalArticleScientificpeer-review

    24 Citations (Scopus)

    Abstract

    Hairy roots of Catharanthus roseus were cultivated in three different types of bioreactors. The best growth and indole alkaloid production was achieved in an airsparged bioreactor with no other mixing. In the stirred bioreactor or in the bioreactor with medium circulation the roots did not grow, suggesting that hairy roots of C. roseus are more sensitive to stress than root cultures of many other plant species.
    Original languageEnglish
    Pages (from-to)61-66
    Number of pages6
    JournalBiotechnology Techniques
    Volume8
    Issue number1
    DOIs
    Publication statusPublished - 1994
    MoE publication typeA1 Journal article-refereed

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    Catharanthus
    Bioreactors
    Indole Alkaloids
    Growth

    Cite this

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    title = "Bioreactor studies on hairy root cultures of Catharanthus roseus: Comparison of three bioreactor types",
    abstract = "Hairy roots of Catharanthus roseus were cultivated in three different types of bioreactors. The best growth and indole alkaloid production was achieved in an airsparged bioreactor with no other mixing. In the stirred bioreactor or in the bioreactor with medium circulation the roots did not grow, suggesting that hairy roots of C. roseus are more sensitive to stress than root cultures of many other plant species.",
    author = "Anna-Maria Nuutila and Leena Toivonen and Veli Kauppinen",
    note = "Project code: BIO9001",
    year = "1994",
    doi = "10.1007/BF00207635",
    language = "English",
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    Bioreactor studies on hairy root cultures of Catharanthus roseus : Comparison of three bioreactor types. / Nuutila, Anna-Maria; Toivonen, Leena; Kauppinen, Veli.

    In: Biotechnology Techniques, Vol. 8, No. 1, 1994, p. 61-66.

    Research output: Contribution to journalArticleScientificpeer-review

    TY - JOUR

    T1 - Bioreactor studies on hairy root cultures of Catharanthus roseus

    T2 - Comparison of three bioreactor types

    AU - Nuutila, Anna-Maria

    AU - Toivonen, Leena

    AU - Kauppinen, Veli

    N1 - Project code: BIO9001

    PY - 1994

    Y1 - 1994

    N2 - Hairy roots of Catharanthus roseus were cultivated in three different types of bioreactors. The best growth and indole alkaloid production was achieved in an airsparged bioreactor with no other mixing. In the stirred bioreactor or in the bioreactor with medium circulation the roots did not grow, suggesting that hairy roots of C. roseus are more sensitive to stress than root cultures of many other plant species.

    AB - Hairy roots of Catharanthus roseus were cultivated in three different types of bioreactors. The best growth and indole alkaloid production was achieved in an airsparged bioreactor with no other mixing. In the stirred bioreactor or in the bioreactor with medium circulation the roots did not grow, suggesting that hairy roots of C. roseus are more sensitive to stress than root cultures of many other plant species.

    U2 - 10.1007/BF00207635

    DO - 10.1007/BF00207635

    M3 - Article

    VL - 8

    SP - 61

    EP - 66

    JO - Biotechnology Techniques

    JF - Biotechnology Techniques

    SN - 0951-208X

    IS - 1

    ER -