Bioreactor studies on hairy root cultures of Catharanthus roseus: Comparison of three bioreactor types

Anna-Maria Nuutila, Leena Toivonen, Veli Kauppinen

    Research output: Contribution to journalArticleScientificpeer-review

    26 Citations (Scopus)


    Hairy roots of Catharanthus roseus were cultivated in three different types of bioreactors. The best growth and indole alkaloid production was achieved in an airsparged bioreactor with no other mixing. In the stirred bioreactor or in the bioreactor with medium circulation the roots did not grow, suggesting that hairy roots of C. roseus are more sensitive to stress than root cultures of many other plant species.
    Original languageEnglish
    Pages (from-to)61-66
    Number of pages6
    JournalBiotechnology Techniques
    Issue number1
    Publication statusPublished - 1994
    MoE publication typeA1 Journal article-refereed


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