Abstract
Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy method developed to treat patients with certain malignant tumours. To date, over 300 treatments have been carried out at the Finnish BNCT facility in various on-going and past clinical trials. In this technical review, we discuss our research work in the field of medical physics to form the groundwork for the Finnish BNCT patient treatments, as well as the possibilities to further develop and optimize the method in the future. Accordingly, the following aspects are described: neutron sources, beam dosimetry, treatment planning, boron imaging and determination, and finally the possibilities to detect the efficacy and effects of BNCT on patients.
Original language | English |
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Pages (from-to) | 233-248 |
Number of pages | 16 |
Journal | Physica Medica |
Volume | 29 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 May 2013 |
MoE publication type | A1 Journal article-refereed |
Keywords
- Beam dosimetry
- Boron imaging and determination
- Diffusion imaging
- Dose calculation
- Image registration
- Neutron dosimetry
- Neutron sources
- Treatment planning