Characterization of fusion protein monolayer properties With dual-gate graphene FETs

Miika Soikkeli, Markku Kainlauri, Katri Kurppa, J. Niinistö, Sanna Arpiainen, Jussi Joensuu, Mika Prunnila, M. Ritala, M. Leskelä, M. Linder, Jouni Ahopelto

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

Abstract

Biosensing devices based on graphene and nanostructures facilitate label-free detection with sensitivities beyond traditional methods. Specific biorecognition relies on selective immobilization of analytes in the close vicinity of the sensor surface. The sensitivity of the biosensor is defined by the height and polarizability of the dielectric layer that forms at the interface of graphene and the electrolyte and this layer is strongly modified by the protein structure. Even though liquid phase analysis is based on liquid gate, additional back gate under the sensing material increases the amount of information obtainable from the system. Unstability of the traditional gate dielectric, silicon dioxide, in electrolytes has turned the interest to high-k oxides. For example, HfO2 as gate dielectric reduces the gate leakage current when compared to SiO2.
Original languageEnglish
Title of host publicationBALD2014 Abstract book
Publication statusPublished - 2014
MoE publication typeNot Eligible
Event12th International Baltic Conference on Atomic Layer Deposition, Baltic ALD 2014 - Helsinki, Finland
Duration: 12 May 201413 May 2014
Conference number: 12
http://www.aldcoe.fi/bald2014/program.pdf (Program)
http://www.aldcoe.fi/bald2014/posters.pdf (Posters)

Conference

Conference12th International Baltic Conference on Atomic Layer Deposition, Baltic ALD 2014
Abbreviated titleBaltic ALD 2014
CountryFinland
CityHelsinki
Period12/05/1413/05/14
OtherAbstracts reviewed and published.
Internet address

Fingerprint

Graphite
Gate dielectrics
Field effect transistors
Electrolytes
Monolayers
Fusion reactions
Liquids
Biosensors
Leakage currents
Silicon Dioxide
Oxides
Labels
Nanostructures
Proteins
Sensors

Keywords

  • graphene
  • hydrophobin
  • fusion protein
  • biosensor
  • HfO2

Cite this

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title = "Characterization of fusion protein monolayer properties With dual-gate graphene FETs",
abstract = "Biosensing devices based on graphene and nanostructures facilitate label-free detection with sensitivities beyond traditional methods. Specific biorecognition relies on selective immobilization of analytes in the close vicinity of the sensor surface. The sensitivity of the biosensor is defined by the height and polarizability of the dielectric layer that forms at the interface of graphene and the electrolyte and this layer is strongly modified by the protein structure. Even though liquid phase analysis is based on liquid gate, additional back gate under the sensing material increases the amount of information obtainable from the system. Unstability of the traditional gate dielectric, silicon dioxide, in electrolytes has turned the interest to high-k oxides. For example, HfO2 as gate dielectric reduces the gate leakage current when compared to SiO2.",
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author = "Miika Soikkeli and Markku Kainlauri and Katri Kurppa and J. Niinist{\"o} and Sanna Arpiainen and Jussi Joensuu and Mika Prunnila and M. Ritala and M. Leskel{\"a} and M. Linder and Jouni Ahopelto",
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Soikkeli, M, Kainlauri, M, Kurppa, K, Niinistö, J, Arpiainen, S, Joensuu, J, Prunnila, M, Ritala, M, Leskelä, M, Linder, M & Ahopelto, J 2014, Characterization of fusion protein monolayer properties With dual-gate graphene FETs. in BALD2014 Abstract book. 12th International Baltic Conference on Atomic Layer Deposition, Baltic ALD 2014, Helsinki, Finland, 12/05/14.

Characterization of fusion protein monolayer properties With dual-gate graphene FETs. / Soikkeli, Miika; Kainlauri, Markku; Kurppa, Katri; Niinistö, J.; Arpiainen, Sanna; Joensuu, Jussi; Prunnila, Mika; Ritala, M.; Leskelä, M.; Linder, M.; Ahopelto, Jouni.

BALD2014 Abstract book. 2014.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific

TY - CHAP

T1 - Characterization of fusion protein monolayer properties With dual-gate graphene FETs

AU - Soikkeli, Miika

AU - Kainlauri, Markku

AU - Kurppa, Katri

AU - Niinistö, J.

AU - Arpiainen, Sanna

AU - Joensuu, Jussi

AU - Prunnila, Mika

AU - Ritala, M.

AU - Leskelä, M.

AU - Linder, M.

AU - Ahopelto, Jouni

N1 - Project code: 73337

PY - 2014

Y1 - 2014

N2 - Biosensing devices based on graphene and nanostructures facilitate label-free detection with sensitivities beyond traditional methods. Specific biorecognition relies on selective immobilization of analytes in the close vicinity of the sensor surface. The sensitivity of the biosensor is defined by the height and polarizability of the dielectric layer that forms at the interface of graphene and the electrolyte and this layer is strongly modified by the protein structure. Even though liquid phase analysis is based on liquid gate, additional back gate under the sensing material increases the amount of information obtainable from the system. Unstability of the traditional gate dielectric, silicon dioxide, in electrolytes has turned the interest to high-k oxides. For example, HfO2 as gate dielectric reduces the gate leakage current when compared to SiO2.

AB - Biosensing devices based on graphene and nanostructures facilitate label-free detection with sensitivities beyond traditional methods. Specific biorecognition relies on selective immobilization of analytes in the close vicinity of the sensor surface. The sensitivity of the biosensor is defined by the height and polarizability of the dielectric layer that forms at the interface of graphene and the electrolyte and this layer is strongly modified by the protein structure. Even though liquid phase analysis is based on liquid gate, additional back gate under the sensing material increases the amount of information obtainable from the system. Unstability of the traditional gate dielectric, silicon dioxide, in electrolytes has turned the interest to high-k oxides. For example, HfO2 as gate dielectric reduces the gate leakage current when compared to SiO2.

KW - graphene

KW - hydrophobin

KW - fusion protein

KW - biosensor

KW - HfO2

M3 - Conference abstract in proceedings

BT - BALD2014 Abstract book

ER -