Coacervation of resilin fusion proteins containing terminal functionalities

Wenwen Fang, Nonappa, Marika Vitikainen, Pezhman Mohammadi, Salla Koskela, Miika Soikkeli, Ann Westerholm-Parvinen, Christopher P. Landowski, Merja Penttilä, Markus B. Linder, Päivi Laaksonen (Corresponding Author)

    Research output: Contribution to journalArticleScientificpeer-review

    10 Citations (Scopus)


    Liquid-liquid phase transition known as coacervation of resilin-like-peptide fusion proteins containing different terminal domains were investigated. Two different modular proteins were designed and produced and their behavior were compared to a resilin-like-peptide without terminal domains. The size of the particle-like coacervates was modulated by the protein concentration, pH and temperature. The morphology and three-dimensional (3D) structural details of the coacervate particles were investigated by cryogenic transmission electron microscopy (cryo-TEM) and tomography (cryo-ET) reconstruction. Selective adhesion of the coacervates on cellulose and graphene surfaces was demonstrated.

    Original languageEnglish
    Pages (from-to)590-596
    Number of pages7
    JournalColloids and Surfaces B: Biointerfaces
    Publication statusPublished - 1 Nov 2018
    MoE publication typeA1 Journal article-refereed


    • Coacervation
    • Resilin
    • Selective adhesion
    • Self-assembly
    • Tomography


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