Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment

A. Sdobnov, A. Bykov, A. Popov, I. Lihacova, A. Lihachev, J. Spigulis, I. Meglinski

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

Abstract

Laser Speckle Contrast Imaging (LSCI) is a powerful low-cost method for visualization of flow, microcirculation and blood perfusion. Due to the fact that diseased and healthy tissues has different blood perfusion, LSCI can be a perspective tool for cancer diagnostics and discrimination between different types of tissues. Previously, multispectral diffuse reflectance imaging method for melanoma diagnostics has been introduced. In this work, multi-wavelength (532-, 655- and 850- nm) LSCI technique combined with hyperspectral camera and diffuse reflectance imaging method will be used for assessment of tissues with different skin perfusion properties. An in vivo experiment with occlusion in human finger was performed serving as a model of tissues with different perfusion properties. The proposed method still requires further development and improvements to become a real clinical laboratory tool for non-invasive skin cancer diagnostics.

Original languageEnglish
Title of host publicationNovel Biophotonics Techniques and Applications V
EditorsArjen Amelink, Seemantini K. Nadkarni
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Electronic)978-1-51062-844-1
ISBN (Print)978-1-51062-843-4
DOIs
Publication statusPublished - 1 Jan 2019
MoE publication typeA4 Article in a conference publication
EventEuropean Conference on Biomedical Optics, ECBO 2019 - München, Germany
Duration: 23 Jun 201927 Jun 2019

Publication series

SeriesProgress in Biomedical Optics and Imaging
Number60
Volume20
ISSN1605-7422
SeriesProceedings of SPIE
Volume11075
ISSN0277-786X

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2019
CountryGermany
CityMünchen
Period23/06/1927/06/19

Keywords

  • hyperspectral imaging
  • skin cancer
  • skin perfusion
  • Speckle
  • speckle contrast
  • speckle imaging

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