Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment

A. Sdobnov; A. Bykov; A. Popov; I. Lihacova; A. Lihachev; J. Spigulis; I. Meglinski

doi:10.1117/12.2526921

Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment

A. Sdobnov^*
, A. Bykov
, A. Popov
, I. Lihacova
, A. Lihachev
, J. Spigulis
, I. Meglinski

^*Corresponding author for this work

Not published at VTT

University of Oulu
University of Latvia

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

3 Citations (Scopus)

Abstract

Laser Speckle Contrast Imaging (LSCI) is a powerful low-cost method for visualization of flow, microcirculation and blood perfusion. Due to the fact that diseased and healthy tissues has different blood perfusion, LSCI can be a perspective tool for cancer diagnostics and discrimination between different types of tissues. Previously, multispectral diffuse reflectance imaging method for melanoma diagnostics has been introduced. In this work, multi-wavelength (532-, 655- and 850- nm) LSCI technique combined with hyperspectral camera and diffuse reflectance imaging method will be used for assessment of tissues with different skin perfusion properties. An in vivo experiment with occlusion in human finger was performed serving as a model of tissues with different perfusion properties. The proposed method still requires further development and improvements to become a real clinical laboratory tool for non-invasive skin cancer diagnostics.

Original language	English
Title of host publication	Novel Biophotonics Techniques and Applications V
Editors	Arjen Amelink, Seemantini K. Nadkarni
Publisher	International Society for Optics and Photonics SPIE
ISBN (Electronic)	9781510628434
ISBN (Print)	978-1-51062-843-4
DOIs	https://doi.org/10.1117/12.2526921
Publication status	Published - 1 Jan 2019
MoE publication type	A4 Article in a conference publication
Event	European Conference on Biomedical Optics, ECBO 2019 - München, Germany Duration: 23 Jun 2019 → 27 Jun 2019

Publication series

Series	Progress in Biomedical Optics and Imaging
Number	60
Volume	20
ISSN	1605-7422

Series	Proceedings of SPIE
Volume	11075
ISSN	0277-786X

Conference

Conference	European Conference on Biomedical Optics, ECBO 2019
Country/Territory	Germany
City	München
Period	23/06/19 → 27/06/19

Funding

A.S was supported by Finnish Cultural Foundation (00180998). I.L. was supported by European Regional Development Fund project “Development and clinical validation of a novel cost effective multi-modal methodology for early diagnostics of skin cancers” (No. 1.1.1.2/16/I/001, agreement No. 1.1.1.2/VIAA/1/16/052). A.B. and A.P. acknowledge support provided by the Academy of Finland (290596).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

hyperspectral imaging
skin cancer
skin perfusion
Speckle
speckle contrast
speckle imaging

Access to Document

10.1117/12.2526921

Cite this

Sdobnov, A., Bykov, A., Popov, A., Lihacova, I., Lihachev, A., Spigulis, J., & Meglinski, I. (2019). Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment. In A. Amelink, & S. K. Nadkarni (Eds.), Novel Biophotonics Techniques and Applications V Article 110751F International Society for Optics and Photonics SPIE. https://doi.org/10.1117/12.2526921

Sdobnov, A. ; Bykov, A. ; Popov, A. et al. / Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment. Novel Biophotonics Techniques and Applications V. editor / Arjen Amelink ; Seemantini K. Nadkarni. International Society for Optics and Photonics SPIE, 2019. (Progress in Biomedical Optics and Imaging; No. 60, Vol. 20). (Proceedings of SPIE, Vol. 11075).

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title = "Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment",

abstract = "Laser Speckle Contrast Imaging (LSCI) is a powerful low-cost method for visualization of flow, microcirculation and blood perfusion. Due to the fact that diseased and healthy tissues has different blood perfusion, LSCI can be a perspective tool for cancer diagnostics and discrimination between different types of tissues. Previously, multispectral diffuse reflectance imaging method for melanoma diagnostics has been introduced. In this work, multi-wavelength (532-, 655- and 850- nm) LSCI technique combined with hyperspectral camera and diffuse reflectance imaging method will be used for assessment of tissues with different skin perfusion properties. An in vivo experiment with occlusion in human finger was performed serving as a model of tissues with different perfusion properties. The proposed method still requires further development and improvements to become a real clinical laboratory tool for non-invasive skin cancer diagnostics.",

keywords = "hyperspectral imaging, skin cancer, skin perfusion, Speckle, speckle contrast, speckle imaging",

author = "A. Sdobnov and A. Bykov and A. Popov and I. Lihacova and A. Lihachev and J. Spigulis and I. Meglinski",

note = "Funding Information: A.S was supported by Finnish Cultural Foundation (00180998). I.L. was supported by European Regional Development Fund project {"}Development and clinical validation of a novel cost effective multi-modal methodology for early diagnostics of skin cancers{"} (No. 1.1.1.2/16/I/001, agreement No. 1.1.1.2/VIAA/1/16/052). A.B. and A.P. acknowledge support provided by the Academy of Finland (290596). Funding Information: A.S was supported by Finnish Cultural Foundation (00180998). I.L. was supported by European Regional Development Fund project “Development and clinical validation of a novel cost effective multi-modal methodology for early diagnostics of skin cancers” (No. 1.1.1.2/16/I/001, agreement No. 1.1.1.2/VIAA/1/16/052). A.B. and A.P. acknowledge support provided by the Academy of Finland (290596). Publisher Copyright: Copyright {\textcopyright} 2018 SPIE. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.; European Conference on Biomedical Optics, ECBO 2019 ; Conference date: 23-06-2019 Through 27-06-2019",

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Sdobnov, A, Bykov, A, Popov, A, Lihacova, I, Lihachev, A, Spigulis, J & Meglinski, I 2019, Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment. in A Amelink & SK Nadkarni (eds), Novel Biophotonics Techniques and Applications V., 110751F, International Society for Optics and Photonics SPIE, Progress in Biomedical Optics and Imaging, no. 60, vol. 20, Proceedings of SPIE, vol. 11075, European Conference on Biomedical Optics, ECBO 2019, München, Bavaria, Germany, 23/06/19. https://doi.org/10.1117/12.2526921

Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment. / Sdobnov, A.; Bykov, A.; Popov, A. et al.
Novel Biophotonics Techniques and Applications V. ed. / Arjen Amelink; Seemantini K. Nadkarni. International Society for Optics and Photonics SPIE, 2019. 110751F (Progress in Biomedical Optics and Imaging; No. 60, Vol. 20). (Proceedings of SPIE, Vol. 11075).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

TY - GEN

T1 - Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment

AU - Sdobnov, A.

AU - Bykov, A.

AU - Popov, A.

AU - Lihacova, I.

AU - Lihachev, A.

AU - Spigulis, J.

AU - Meglinski, I.

N1 - Funding Information: A.S was supported by Finnish Cultural Foundation (00180998). I.L. was supported by European Regional Development Fund project "Development and clinical validation of a novel cost effective multi-modal methodology for early diagnostics of skin cancers" (No. 1.1.1.2/16/I/001, agreement No. 1.1.1.2/VIAA/1/16/052). A.B. and A.P. acknowledge support provided by the Academy of Finland (290596). Funding Information: A.S was supported by Finnish Cultural Foundation (00180998). I.L. was supported by European Regional Development Fund project “Development and clinical validation of a novel cost effective multi-modal methodology for early diagnostics of skin cancers” (No. 1.1.1.2/16/I/001, agreement No. 1.1.1.2/VIAA/1/16/052). A.B. and A.P. acknowledge support provided by the Academy of Finland (290596). Publisher Copyright: Copyright © 2018 SPIE. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Laser Speckle Contrast Imaging (LSCI) is a powerful low-cost method for visualization of flow, microcirculation and blood perfusion. Due to the fact that diseased and healthy tissues has different blood perfusion, LSCI can be a perspective tool for cancer diagnostics and discrimination between different types of tissues. Previously, multispectral diffuse reflectance imaging method for melanoma diagnostics has been introduced. In this work, multi-wavelength (532-, 655- and 850- nm) LSCI technique combined with hyperspectral camera and diffuse reflectance imaging method will be used for assessment of tissues with different skin perfusion properties. An in vivo experiment with occlusion in human finger was performed serving as a model of tissues with different perfusion properties. The proposed method still requires further development and improvements to become a real clinical laboratory tool for non-invasive skin cancer diagnostics.

AB - Laser Speckle Contrast Imaging (LSCI) is a powerful low-cost method for visualization of flow, microcirculation and blood perfusion. Due to the fact that diseased and healthy tissues has different blood perfusion, LSCI can be a perspective tool for cancer diagnostics and discrimination between different types of tissues. Previously, multispectral diffuse reflectance imaging method for melanoma diagnostics has been introduced. In this work, multi-wavelength (532-, 655- and 850- nm) LSCI technique combined with hyperspectral camera and diffuse reflectance imaging method will be used for assessment of tissues with different skin perfusion properties. An in vivo experiment with occlusion in human finger was performed serving as a model of tissues with different perfusion properties. The proposed method still requires further development and improvements to become a real clinical laboratory tool for non-invasive skin cancer diagnostics.

KW - hyperspectral imaging

KW - skin cancer

KW - skin perfusion

KW - Speckle

KW - speckle contrast

KW - speckle imaging

UR - https://www.scopus.com/pages/publications/85074285810

U2 - 10.1117/12.2526921

DO - 10.1117/12.2526921

M3 - Conference article in proceedings

AN - SCOPUS:85074285810

SN - 978-1-51062-843-4

T3 - Progress in Biomedical Optics and Imaging

BT - Novel Biophotonics Techniques and Applications V

A2 - Amelink, Arjen

A2 - Nadkarni, Seemantini K.

PB - International Society for Optics and Photonics SPIE

T2 - European Conference on Biomedical Optics, ECBO 2019

Y2 - 23 June 2019 through 27 June 2019

ER -

Sdobnov A, Bykov A, Popov A, Lihacova I, Lihachev A, Spigulis J et al. Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment. In Amelink A, Nadkarni SK, editors, Novel Biophotonics Techniques and Applications V. International Society for Optics and Photonics SPIE. 2019. 110751F. (Progress in Biomedical Optics and Imaging; No. 60, Vol. 20). (Proceedings of SPIE, Vol. 11075). doi: 10.1117/12.2526921

Combined multi-wavelength laser speckle contrast imaging and diffuse reflectance imaging for skin perfusion assessment

Abstract

Publication series

Conference

Funding

UN SDGs

Keywords

Access to Document

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