Comparative study of dose calculations with SERA and JCDS treatment planning systems

H. Koivunoro; H. Kumada; Tiina Seppälä; Petri Kotiluoto; Iiro Auterinen; Leena Kankaanranta; S. Savolainen

doi:10.1016/j.apradiso.2009.03.092

Comparative study of dose calculations with SERA and JCDS treatment planning systems

H. Koivunoro (Corresponding Author), H. Kumada, Tiina Seppälä, Petri Kotiluoto, Iiro Auterinen, Leena Kankaanranta, S. Savolainen

VTT Technical Research Centre of Finland

Research output: Contribution to journal › Article › Scientific › peer-review

1 Citation (Scopus)

Abstract

Three treatment planning systems developed for clinical boron neutron capture therapy (BNCT) use are SERA developed by INL/Montana State University, NCTPlan developed by the Harvard-MIT and the CNEA group and JAEA computational dosimetry system (JCDS) developed by Japan Atomic Energy Agency (JAEA) in Japan. Previously, performance of the SERA and NCTPlan has been compared in various studies. In this preliminary study, the dose calculations performed with SERA and JCDS systems were compared in single brain cancer patient case with the FiR 1 epithermal neutron beam. A two-field brain cancer treatment plan was performed with the both codes. The dose components to normal brain, tumor and planning target volume (PTV) were calculated and compared in case of one radiation field and combined two fields. The depth dose distributions and the maximum doses in regions of interest were compared. Calculations with the treatment planning systems for the thermal neutron induced (¹⁰B and nitrogen) dose components and photon dose were in good agreement. Higher discrepancy in the fast neutron dose calculations was found. In case of combined two-field treatment plan, overall discrepancy of the maximum weighted dose was ∼3% for normal brain and PTV and ∼4% for tumor dose.

Original language	English
Pages (from-to)	S126-S129
Number of pages	4
Journal	Applied Radiation and Isotopes
Volume	67
Issue number	7-8 Supplement
DOIs	https://doi.org/10.1016/j.apradiso.2009.03.092
Publication status	Published - 1 Jul 2009
MoE publication type	A1 Journal article-refereed
Event	13th International Congress on Neutron Capture Therapy BNCT: A new option against cancer - Florence, Italy Duration: 2 Nov 2008 → 8 Nov 2008

Keywords

Boron neutron capture therapy (BNCT)
Dose calculation
JCDS
MCNP
SERA
Treatment planning

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title = "Comparative study of dose calculations with SERA and JCDS treatment planning systems",

abstract = "Three treatment planning systems developed for clinical boron neutron capture therapy (BNCT) use are SERA developed by INL/Montana State University, NCTPlan developed by the Harvard-MIT and the CNEA group and JAEA computational dosimetry system (JCDS) developed by Japan Atomic Energy Agency (JAEA) in Japan. Previously, performance of the SERA and NCTPlan has been compared in various studies. In this preliminary study, the dose calculations performed with SERA and JCDS systems were compared in single brain cancer patient case with the FiR 1 epithermal neutron beam. A two-field brain cancer treatment plan was performed with the both codes. The dose components to normal brain, tumor and planning target volume (PTV) were calculated and compared in case of one radiation field and combined two fields. The depth dose distributions and the maximum doses in regions of interest were compared. Calculations with the treatment planning systems for the thermal neutron induced (10B and nitrogen) dose components and photon dose were in good agreement. Higher discrepancy in the fast neutron dose calculations was found. In case of combined two-field treatment plan, overall discrepancy of the maximum weighted dose was ∼3% for normal brain and PTV and ∼4% for tumor dose.",

keywords = "Boron neutron capture therapy (BNCT), Dose calculation, JCDS, MCNP, SERA, Treatment planning",

author = "H. Koivunoro and H. Kumada and Tiina Sepp{\"a}l{\"a} and Petri Kotiluoto and Iiro Auterinen and Leena Kankaanranta and S. Savolainen",

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Comparative study of dose calculations with SERA and JCDS treatment planning systems. / Koivunoro, H. (Corresponding Author); Kumada, H.; Seppälä, Tiina; Kotiluoto, Petri ; Auterinen, Iiro; Kankaanranta, Leena; Savolainen, S.

In: Applied Radiation and Isotopes, Vol. 67, No. 7-8 Supplement, 01.07.2009, p. S126-S129.

Research output: Contribution to journal › Article › Scientific › peer-review

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