Comparison of two-stage retention index monitoring capillary gas chromatography and selected ion monitoring capillary gas chromatography

Mass spectrometry as analytical tools

Jouni Enqvist, Maarit Enqvist

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)

Abstract

Two‐stage capillary GC with two‐stage retention index monitoring is an efficient analytical technique which can be used for detection and determination of small amounts of volatile compounds in complex mixtures of hundreds or thousands of other compounds. The system employs two capillary columns, coated with different stationary phases, connected on‐line with the aid of a micro valve; the first column acts as a pre‐separating unit from which unresolved fractions of interest are cut (transferred) into another column for final, interference‐free separation of the compounds to be determined. This technique has been compared with selected ion monitoring capillary GC‐MS using a hydrocarbon mixture as a test sample for comparing resolution, repeatability, and the practical usefulness of the techniques. Results indicate that two‐stage capillary GC is very useful for mixtures containing compounds which produce mostly non‐specific ions in the MS ion source whereas compounds producing specific ions can be easily analyzed by capillary GC – single ion monitoring MS even if they are not perfectly separated by a single capillary column.
Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalHRC Journal of High Resolution Chromatography
Volume17
Issue number3
DOIs
Publication statusPublished - 1994
MoE publication typeA1 Journal article-refereed

Fingerprint

Gas chromatography
Mass spectrometry
Ions
Monitoring
Ion sources
Hydrocarbons
Complex Mixtures

Cite this

@article{aac40ea9bed3475781c98bf30471dc0e,
title = "Comparison of two-stage retention index monitoring capillary gas chromatography and selected ion monitoring capillary gas chromatography: Mass spectrometry as analytical tools",
abstract = "Two‐stage capillary GC with two‐stage retention index monitoring is an efficient analytical technique which can be used for detection and determination of small amounts of volatile compounds in complex mixtures of hundreds or thousands of other compounds. The system employs two capillary columns, coated with different stationary phases, connected on‐line with the aid of a micro valve; the first column acts as a pre‐separating unit from which unresolved fractions of interest are cut (transferred) into another column for final, interference‐free separation of the compounds to be determined. This technique has been compared with selected ion monitoring capillary GC‐MS using a hydrocarbon mixture as a test sample for comparing resolution, repeatability, and the practical usefulness of the techniques. Results indicate that two‐stage capillary GC is very useful for mixtures containing compounds which produce mostly non‐specific ions in the MS ion source whereas compounds producing specific ions can be easily analyzed by capillary GC – single ion monitoring MS even if they are not perfectly separated by a single capillary column.",
author = "Jouni Enqvist and Maarit Enqvist",
year = "1994",
doi = "10.1002/jhrc.1240170304",
language = "English",
volume = "17",
pages = "141--144",
journal = "Journal of Separation Science",
issn = "1615-9306",
publisher = "Wiley-VCH Verlag",
number = "3",

}

Comparison of two-stage retention index monitoring capillary gas chromatography and selected ion monitoring capillary gas chromatography : Mass spectrometry as analytical tools. / Enqvist, Jouni; Enqvist, Maarit.

In: HRC Journal of High Resolution Chromatography, Vol. 17, No. 3, 1994, p. 141-144.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Comparison of two-stage retention index monitoring capillary gas chromatography and selected ion monitoring capillary gas chromatography

T2 - Mass spectrometry as analytical tools

AU - Enqvist, Jouni

AU - Enqvist, Maarit

PY - 1994

Y1 - 1994

N2 - Two‐stage capillary GC with two‐stage retention index monitoring is an efficient analytical technique which can be used for detection and determination of small amounts of volatile compounds in complex mixtures of hundreds or thousands of other compounds. The system employs two capillary columns, coated with different stationary phases, connected on‐line with the aid of a micro valve; the first column acts as a pre‐separating unit from which unresolved fractions of interest are cut (transferred) into another column for final, interference‐free separation of the compounds to be determined. This technique has been compared with selected ion monitoring capillary GC‐MS using a hydrocarbon mixture as a test sample for comparing resolution, repeatability, and the practical usefulness of the techniques. Results indicate that two‐stage capillary GC is very useful for mixtures containing compounds which produce mostly non‐specific ions in the MS ion source whereas compounds producing specific ions can be easily analyzed by capillary GC – single ion monitoring MS even if they are not perfectly separated by a single capillary column.

AB - Two‐stage capillary GC with two‐stage retention index monitoring is an efficient analytical technique which can be used for detection and determination of small amounts of volatile compounds in complex mixtures of hundreds or thousands of other compounds. The system employs two capillary columns, coated with different stationary phases, connected on‐line with the aid of a micro valve; the first column acts as a pre‐separating unit from which unresolved fractions of interest are cut (transferred) into another column for final, interference‐free separation of the compounds to be determined. This technique has been compared with selected ion monitoring capillary GC‐MS using a hydrocarbon mixture as a test sample for comparing resolution, repeatability, and the practical usefulness of the techniques. Results indicate that two‐stage capillary GC is very useful for mixtures containing compounds which produce mostly non‐specific ions in the MS ion source whereas compounds producing specific ions can be easily analyzed by capillary GC – single ion monitoring MS even if they are not perfectly separated by a single capillary column.

U2 - 10.1002/jhrc.1240170304

DO - 10.1002/jhrc.1240170304

M3 - Article

VL - 17

SP - 141

EP - 144

JO - Journal of Separation Science

JF - Journal of Separation Science

SN - 1615-9306

IS - 3

ER -