Conversion of hexuronic acid to hexaric acid

Harry Boer (Inventor), Satu Hildich (Inventor), Peter Richard (Inventor), Merja Penttilä (Inventor)

Research output: PatentPatent


The present invention relates to a method and microbial host strain for converting a hexuronic acid to a hexaric acid. In particular, the invention relates to the con-version of D-galacturonic acid to meso-galactaric acid (mucic acid). The invention also concerns an isolated nucleotide sequence. According to the present method a microbial host strain genetically modified to express uronate dehydrogenase enzyme (EC is contacted with a biomaterial comprising hexuronic acid and the con-version products are recovered. By using the recombinant microorganisms of the present invention it is possible to treat biomaterials comprising hexuronic acids and thereby decrease the amount of hexuronic acids released to the environment.

Patent family as of 9.9.2021
BRPI0923653 A2 20150811 BR2009PI23653 20091222      
BRPI0923653 B1 20201013 BR2009PI23653 20091222      
DE602009034383 D1 20151203 DE200960034383T 20091222      
EP2376620 A1 20111019 EP20090796407 20091222      
EP2376620 B1 20151021 EP20090796407 20091222      
FI20086236 A0 20081223 FI20080006236 20081223      
PL2376620 T3 20160831 PL20090796407T 20091222      
US2012045804 AA 20120223 US20090141736 20091222      
US8895273 BB 20141125 US20090141736 20091222      
WO10072902 A1 20100701 WO2009FI51029 20091222

Link to current patent family on right 

Original languageEnglish
Patent numberEP2376620
IPCC12P 7/ 44 A I
Priority date22/12/09
Publication statusPublished - 19 Oct 2011
MoE publication typeH1 Granted patent


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