Crystalline cellulose degradation: New insight into the function of cellobiohydrolases

Tuula Teeri

Research output: Contribution to journalArticleScientificpeer-review

556 Citations (Scopus)


Cellulose is an important industrial raw material and a source of renewable energy. The crystalline structure of cellulose is biodegradable by the combined activities of many different enzymes. Cellobiohydrolases, the key cellulases, have extended tunnel-shaped active sites. Owing to the design of their active-site tunnels, they do not make cuts within cellulose chains but release cellobiose from the chain ends. Cellobiohydrolases may therefore prove to be useful for achieving subtle modifications of fiber properties in paper or textiles without the loss of fiber strength commonly observed with other cellulases.

Original languageEnglish
Pages (from-to)160-167
JournalTrends in Biotechnology
Issue number5
Publication statusPublished - 1997
MoE publication typeA1 Journal article-refereed


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