Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 10263-10267 |
| Journal | Angewandte Chemie: International Edition |
| Volume | 55 |
| Issue number | 35 |
| DOIs | |
| Publication status | Published - 2016 |
| MoE publication type | A1 Journal article-refereed |
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Keywords
- echogenicity
- fluorocarbons
- hydrophobin
- interfacial films
- ultrasound imaging
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Design of highly stable echogenic microbubbles through controlled assembly of their hydrophobin shell. / Gazzera, Lara; Milani, Roberto; Pirrie, Lisa; Schmutz, Marc; Blanck, Christian; Resnati, Giuseppe; Metrangolo, Pierangelo (Corresponding Author); Krafft, Marie Pierre (Corresponding Author).
In: Angewandte Chemie: International Edition, Vol. 55, No. 35, 2016, p. 10263-10267.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Design of highly stable echogenic microbubbles through controlled assembly of their hydrophobin shell
AU - Gazzera, Lara
AU - Milani, Roberto
AU - Pirrie, Lisa
AU - Schmutz, Marc
AU - Blanck, Christian
AU - Resnati, Giuseppe
AU - Metrangolo, Pierangelo
AU - Krafft, Marie Pierre
PY - 2016
Y1 - 2016
N2 - Dispersing hydrophobin HFBII under air saturated with perfluorohexane gas limits HFBII aggregation to nanometer-sizes. Critical basic findings include an unusual co-adsorption effect caused by the fluorocarbon gas, a strong acceleration of HFBII adsorption at the air/water interface, the incorporation of perfluorohexane into the interfacial film, the suppression of the fluid-to-solid 2D phase transition exhibited by HFBII monolayers under air, and a drastic change in film elasticity of both Gibbs and Langmuir films. As a result, perfluorohexane allows the formation of homogenous populations of spherical, narrowly dispersed, exceptionally stable, and echogenic microbubbles.
AB - Dispersing hydrophobin HFBII under air saturated with perfluorohexane gas limits HFBII aggregation to nanometer-sizes. Critical basic findings include an unusual co-adsorption effect caused by the fluorocarbon gas, a strong acceleration of HFBII adsorption at the air/water interface, the incorporation of perfluorohexane into the interfacial film, the suppression of the fluid-to-solid 2D phase transition exhibited by HFBII monolayers under air, and a drastic change in film elasticity of both Gibbs and Langmuir films. As a result, perfluorohexane allows the formation of homogenous populations of spherical, narrowly dispersed, exceptionally stable, and echogenic microbubbles.
KW - echogenicity
KW - fluorocarbons
KW - hydrophobin
KW - interfacial films
KW - ultrasound imaging
U2 - 10.1002/anie.201603706
DO - 10.1002/anie.201603706
M3 - Article
VL - 55
SP - 10263
EP - 10267
JO - Angewandte Chemie: International Edition
JF - Angewandte Chemie: International Edition
SN - 1433-7851
IS - 35
ER -