Designing inorganic light-protective skin nanotechnology products

Alexey P. Popov; Andrei V. Zvyagin; Juergen Lademann; Michael S. Roberts; Washington Sanchez; Alexander V. Priezzhev; Risto Myllylä

doi:10.1166/jbn.2010.1144

Designing inorganic light-protective skin nanotechnology products

Alexey P. Popov, Andrei V. Zvyagin, Juergen Lademann, Michael S. Roberts, Washington Sanchez, Alexander V. Priezzhev, Risto Myllylä

Not published at VTT

Research output: Contribution to journal › Review Article › peer-review

60 Citations (Scopus)

Abstract

In this review, we discuss the use of inorganic nanoparticles, mainly zinc oxide (ZnO) and titanium dioxide (TiO₂), for sunscreen applications considering their intrinsic physical properties and the Mie theory. These properties cause, from one side, attenuation of the ultraviolet light by absorption and scattering (dependent on a particle size), which is the purpose sunscreens are designed for, and formation of free radicals (i.e., phototoxicity) during this process-from the other. Particle penetration into skin is also an important issue addressed in this review due to possible adverse effects associated with interaction between nanoparticles and skin living cells.

Original language	English
Pages (from-to)	432-451
Number of pages	20
Journal	Journal of Biomedical Nanotechnology
Volume	6
Issue number	5
DOIs	https://doi.org/10.1166/jbn.2010.1144
Publication status	Published - 1 Oct 2010
MoE publication type	A2 Review article in a scientific journal

Keywords

Absorption
Mie theory
Monte Carlo simulation
Nanoparticles
Penetration
Scattering
Skin
Stratum corneum
Sunscreen
TiO
Toxicity
UV
ZnO

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10.1166/jbn.2010.1144

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title = "Designing inorganic light-protective skin nanotechnology products",

abstract = "In this review, we discuss the use of inorganic nanoparticles, mainly zinc oxide (ZnO) and titanium dioxide (TiO2), for sunscreen applications considering their intrinsic physical properties and the Mie theory. These properties cause, from one side, attenuation of the ultraviolet light by absorption and scattering (dependent on a particle size), which is the purpose sunscreens are designed for, and formation of free radicals (i.e., phototoxicity) during this process-from the other. Particle penetration into skin is also an important issue addressed in this review due to possible adverse effects associated with interaction between nanoparticles and skin living cells.",

keywords = "Absorption, Mie theory, Monte Carlo simulation, Nanoparticles, Penetration, Scattering, Skin, Stratum corneum, Sunscreen, TiO, Toxicity, UV, ZnO",

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AU - Popov, Alexey P.

AU - Zvyagin, Andrei V.

AU - Lademann, Juergen

AU - Roberts, Michael S.

AU - Sanchez, Washington

AU - Priezzhev, Alexander V.

AU - Myllylä, Risto

PY - 2010/10/1

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AB - In this review, we discuss the use of inorganic nanoparticles, mainly zinc oxide (ZnO) and titanium dioxide (TiO2), for sunscreen applications considering their intrinsic physical properties and the Mie theory. These properties cause, from one side, attenuation of the ultraviolet light by absorption and scattering (dependent on a particle size), which is the purpose sunscreens are designed for, and formation of free radicals (i.e., phototoxicity) during this process-from the other. Particle penetration into skin is also an important issue addressed in this review due to possible adverse effects associated with interaction between nanoparticles and skin living cells.

KW - Absorption

KW - Mie theory

KW - Monte Carlo simulation

KW - Nanoparticles

KW - Penetration

KW - Scattering

KW - Skin

KW - Stratum corneum

KW - Sunscreen

KW - TiO

KW - Toxicity

KW - UV

KW - ZnO

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Designing inorganic light-protective skin nanotechnology products

Abstract

Keywords

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