Development of selection criteria for probiotic strains to assess their potential in functional foods: A Nordic and European approach

Seppo Salminen, Minna Laine, Atte von Wright, Jaana Vuopio-Varkila, Timo Korhonen, Tiina Mattila-Sandholm

Research output: Contribution to journalArticleScientificpeer-review

Abstract

The beneficial effects of probiotic bacteria have been suggested for a century, but until now mostly anecdotal evidence has been available to support these beliefs.The main emphasis has been on development of new and more effective probiotics and only recently in validation of probiotic effects in clinical studies. This review is intended to explain the Nordic and European achievements and future plans in the development of new and more effective probiotic strains. The summary includes data on assessing new and novel methodologies for strain selection, including adhesion, colonization, potential for immune effects via cytokine release, use of gastrointestinal model systems and antigenotoxic properties. Also, first results and plans for the assessment of strains and validation of novel methodologies in pilot human trials are discussed. As a conclusion, the present state of art in the projects is given with plans on future research areas and new developments.
Original languageEnglish
Pages (from-to)61-67
Number of pages7
JournalBioscience and Microflora
Volume15
Issue number2
DOIs
Publication statusPublished - 1996
MoE publication typeA1 Journal article-refereed

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Functional Food
Probiotics
Patient Selection
Cytokines
Bacteria

Cite this

Salminen, Seppo ; Laine, Minna ; Wright, Atte von ; Vuopio-Varkila, Jaana ; Korhonen, Timo ; Mattila-Sandholm, Tiina. / Development of selection criteria for probiotic strains to assess their potential in functional foods : A Nordic and European approach. In: Bioscience and Microflora. 1996 ; Vol. 15, No. 2. pp. 61-67.
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author = "Seppo Salminen and Minna Laine and Wright, {Atte von} and Jaana Vuopio-Varkila and Timo Korhonen and Tiina Mattila-Sandholm",
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Development of selection criteria for probiotic strains to assess their potential in functional foods : A Nordic and European approach. / Salminen, Seppo; Laine, Minna; Wright, Atte von; Vuopio-Varkila, Jaana; Korhonen, Timo; Mattila-Sandholm, Tiina.

In: Bioscience and Microflora, Vol. 15, No. 2, 1996, p. 61-67.

Research output: Contribution to journalArticleScientificpeer-review

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