Abstract
We present a high-throughput roll-to-roll (R2R) manufacturing process
for foil-based polymethyl methacrylate (PMMA) chips of excellent optical
quality. These disposable, R2R hot embossed microfluidic chips are used
for the identification of the antibiotic resistance genemecA in Staphylococcus epidermidis. R2R hot embossing is an emerging manufacturing technology for polymer
microfluidic devices. It is based on continuous feeding of a
thermoplastic foil through a pressurized area between a heated embossing
cylinder and a blank counter cylinder. Although mass fabrication of
foil-based microfluidic chips and their use for biological applications
were foreseen already some years ago, no such studies have been
published previously.
Original language | English |
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Pages (from-to) | 333-339 |
Journal | Lab on a Chip |
Volume | 12 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2012 |
MoE publication type | A1 Journal article-refereed |