Abstract
The addition of Barton's base has a dramatic effect on the classic rhodium(III)-mediated hydrogenations promoted by Wilkinson′s catalyst. Following the initial oxidative addition, a barrierless reductive elimination of HCl from the traditional rhodium(III) intermediates instantly produces a rhodium(I) monohydride species, which is remarkably reactive in the hydrogenation of several internal alkynes and functionalized trisubstituted alkenes. The direct formation of this species is unprecedented upon addition of molecular hydrogen and its catalytic potential has been hitherto barely explored.
Original language | English |
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Pages (from-to) | 14321-14325 |
Number of pages | 5 |
Journal | Angewandte Chemie: International Edition |
Volume | 54 |
Issue number | 48 |
DOIs | |
Publication status | Published - 23 Nov 2015 |
MoE publication type | A1 Journal article-refereed |
Keywords
- density functional calculations
- homogeneous hydrogenation
- reaction mechanisms
- rhodium(I)
- Wilkinson's catalyst