Domain function in Trichoderma reesei cellobiohydrolases

Tuula Teeri (Corresponding Author), Tapani Reinikainen, Laura Ruohonen, Alwyn Jones, Jonathan Knowles

    Research output: Contribution to journalArticleScientificpeer-review

    58 Citations (Scopus)

    Abstract

    The filamentous fungus, Trichoderma reesei produces all of the enzymatic activities required for efficient hydrolysis of highly ordered crystalline cellulose. All the principal enzymes involved in cellulose hydrolysis possess two functional domains, one directly involved in catalysis and the other in substrate recognition and binding. The availability of high-resolution three dimensional structures of the two domains allows genetic engineering to be used for detailed structure-function studies of these important enzymes.
    Original languageEnglish
    Pages (from-to)169-176
    Number of pages8
    JournalJournal of Biotechnology
    Volume24
    Issue number2
    DOIs
    Publication statusPublished - 1992
    MoE publication typeA1 Journal article-refereed

      Fingerprint

    Cite this

    Teeri, T., Reinikainen, T., Ruohonen, L., Jones, A., & Knowles, J. (1992). Domain function in Trichoderma reesei cellobiohydrolases. Journal of Biotechnology, 24(2), 169-176. https://doi.org/10.1016/0168-1656(92)90120-X