Domain function in Trichoderma reesei cellobiohydrolases

Tuula Teeri (Corresponding Author), Tapani Reinikainen, Laura Ruohonen, Alwyn Jones, Jonathan Knowles

    Research output: Contribution to journalArticleScientificpeer-review

    58 Citations (Scopus)

    Abstract

    The filamentous fungus, Trichoderma reesei produces all of the enzymatic activities required for efficient hydrolysis of highly ordered crystalline cellulose. All the principal enzymes involved in cellulose hydrolysis possess two functional domains, one directly involved in catalysis and the other in substrate recognition and binding. The availability of high-resolution three dimensional structures of the two domains allows genetic engineering to be used for detailed structure-function studies of these important enzymes.
    Original languageEnglish
    Pages (from-to)169-176
    Number of pages8
    JournalJournal of Biotechnology
    Volume24
    Issue number2
    DOIs
    Publication statusPublished - 1992
    MoE publication typeA1 Journal article-refereed

    Fingerprint

    Cellulose 1,4-beta-Cellobiosidase
    Trichoderma
    Cellulose
    Hydrolysis
    Enzymes
    Genetic engineering
    Genetic Engineering
    Fungi
    Catalysis
    Availability
    Crystalline materials
    Substrates

    Cite this

    Teeri, T., Reinikainen, T., Ruohonen, L., Jones, A., & Knowles, J. (1992). Domain function in Trichoderma reesei cellobiohydrolases. Journal of Biotechnology, 24(2), 169-176. https://doi.org/10.1016/0168-1656(92)90120-X
    Teeri, Tuula ; Reinikainen, Tapani ; Ruohonen, Laura ; Jones, Alwyn ; Knowles, Jonathan. / Domain function in Trichoderma reesei cellobiohydrolases. In: Journal of Biotechnology. 1992 ; Vol. 24, No. 2. pp. 169-176.
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    abstract = "The filamentous fungus, Trichoderma reesei produces all of the enzymatic activities required for efficient hydrolysis of highly ordered crystalline cellulose. All the principal enzymes involved in cellulose hydrolysis possess two functional domains, one directly involved in catalysis and the other in substrate recognition and binding. The availability of high-resolution three dimensional structures of the two domains allows genetic engineering to be used for detailed structure-function studies of these important enzymes.",
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    Teeri, T, Reinikainen, T, Ruohonen, L, Jones, A & Knowles, J 1992, 'Domain function in Trichoderma reesei cellobiohydrolases', Journal of Biotechnology, vol. 24, no. 2, pp. 169-176. https://doi.org/10.1016/0168-1656(92)90120-X

    Domain function in Trichoderma reesei cellobiohydrolases. / Teeri, Tuula (Corresponding Author); Reinikainen, Tapani; Ruohonen, Laura; Jones, Alwyn; Knowles, Jonathan.

    In: Journal of Biotechnology, Vol. 24, No. 2, 1992, p. 169-176.

    Research output: Contribution to journalArticleScientificpeer-review

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    AU - Teeri, Tuula

    AU - Reinikainen, Tapani

    AU - Ruohonen, Laura

    AU - Jones, Alwyn

    AU - Knowles, Jonathan

    N1 - Project code: BIO1004

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    DO - 10.1016/0168-1656(92)90120-X

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