Dose calculations with SERA and JCDS treatment planning systems

H. Koivunoro, H. Kumada, T. Seppälä, Petri Kotiluoto, Iiro Auterinen, L. Kankaanranta, S. Savolainen

    Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

    Abstract

    Three treatment planning systems developed for clinical BNCT use are SERA developed by INL/Montana State University, NCTPlan developed by the HarvardMIT and the CNEA group and JCDS developed by JAEA in Japan. Previously, performance of the SERA and NCTPlan has been compared in various studies. In this preliminary study, the dose calculations performed with SERA and JCDS systems were compared in single brain cancer patient case with the FiR 1 epithermal neutron beam. A twofield brain cancer treatment plan was performed with the both codes. The dose components to normal brain, tumor and planning target volume (PTV) were calculated and compared in case of one radiation field and combined two fields. The depth dose distributions and the maximum doses in regions of interest were compared. Calculations with the treatment planning systems for the thermal neutron induced (10B and nitrogen) dose components and photon dose were in good agreement. Higher discrepancy in the fast neutron dose calculations was found. In case of combined twofield treatment plan, overall discrepancy of the total maximum weighted dose was ~3% for normal brain and PTV and ~4% for tumor dose.
    Original languageEnglish
    Title of host publicationProceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer
    EditorsA. Zonta
    PublisherENEA
    Pages583-586
    ISBN (Print)978-888-28616-7-4
    Publication statusPublished - 2008
    MoE publication typeA4 Article in a conference publication
    Event13th International Congress on Neutron Capture Therapy BNCT: A new option against cancer - Florence, Italy
    Duration: 2 Nov 20088 Nov 2008

    Conference

    Conference13th International Congress on Neutron Capture Therapy BNCT
    CountryItaly
    CityFlorence
    Period2/11/088/11/08

    Fingerprint

    planning
    dosage
    brain
    tumors
    cancer
    neutron beams
    fast neutrons
    thermal neutrons
    radiation distribution
    Japan
    nitrogen
    photons

    Keywords

    • treatment planning
    • dose calculation
    • MCNP
    • SERA
    • JCDS

    Cite this

    Koivunoro, H., Kumada, H., Seppälä, T., Kotiluoto, P., Auterinen, I., Kankaanranta, L., & Savolainen, S. (2008). Dose calculations with SERA and JCDS treatment planning systems. In A. Zonta (Ed.), Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer (pp. 583-586). ENEA.
    Koivunoro, H. ; Kumada, H. ; Seppälä, T. ; Kotiluoto, Petri ; Auterinen, Iiro ; Kankaanranta, L. ; Savolainen, S. / Dose calculations with SERA and JCDS treatment planning systems. Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer. editor / A. Zonta. ENEA, 2008. pp. 583-586
    @inproceedings{ce0f4ec068d24c1085c575ebb515a07a,
    title = "Dose calculations with SERA and JCDS treatment planning systems",
    abstract = "Three treatment planning systems developed for clinical BNCT use are SERA developed by INL/Montana State University, NCTPlan developed by the HarvardMIT and the CNEA group and JCDS developed by JAEA in Japan. Previously, performance of the SERA and NCTPlan has been compared in various studies. In this preliminary study, the dose calculations performed with SERA and JCDS systems were compared in single brain cancer patient case with the FiR 1 epithermal neutron beam. A twofield brain cancer treatment plan was performed with the both codes. The dose components to normal brain, tumor and planning target volume (PTV) were calculated and compared in case of one radiation field and combined two fields. The depth dose distributions and the maximum doses in regions of interest were compared. Calculations with the treatment planning systems for the thermal neutron induced (10B and nitrogen) dose components and photon dose were in good agreement. Higher discrepancy in the fast neutron dose calculations was found. In case of combined twofield treatment plan, overall discrepancy of the total maximum weighted dose was ~3{\%} for normal brain and PTV and ~4{\%} for tumor dose.",
    keywords = "treatment planning, dose calculation, MCNP, SERA, JCDS",
    author = "H. Koivunoro and H. Kumada and T. Sepp{\"a}l{\"a} and Petri Kotiluoto and Iiro Auterinen and L. Kankaanranta and S. Savolainen",
    year = "2008",
    language = "English",
    isbn = "978-888-28616-7-4",
    pages = "583--586",
    editor = "A. Zonta",
    booktitle = "Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer",
    publisher = "ENEA",
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    Koivunoro, H, Kumada, H, Seppälä, T, Kotiluoto, P, Auterinen, I, Kankaanranta, L & Savolainen, S 2008, Dose calculations with SERA and JCDS treatment planning systems. in A Zonta (ed.), Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer. ENEA, pp. 583-586, 13th International Congress on Neutron Capture Therapy BNCT, Florence, Italy, 2/11/08.

    Dose calculations with SERA and JCDS treatment planning systems. / Koivunoro, H.; Kumada, H.; Seppälä, T.; Kotiluoto, Petri; Auterinen, Iiro; Kankaanranta, L.; Savolainen, S.

    Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer. ed. / A. Zonta. ENEA, 2008. p. 583-586.

    Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

    TY - GEN

    T1 - Dose calculations with SERA and JCDS treatment planning systems

    AU - Koivunoro, H.

    AU - Kumada, H.

    AU - Seppälä, T.

    AU - Kotiluoto, Petri

    AU - Auterinen, Iiro

    AU - Kankaanranta, L.

    AU - Savolainen, S.

    PY - 2008

    Y1 - 2008

    N2 - Three treatment planning systems developed for clinical BNCT use are SERA developed by INL/Montana State University, NCTPlan developed by the HarvardMIT and the CNEA group and JCDS developed by JAEA in Japan. Previously, performance of the SERA and NCTPlan has been compared in various studies. In this preliminary study, the dose calculations performed with SERA and JCDS systems were compared in single brain cancer patient case with the FiR 1 epithermal neutron beam. A twofield brain cancer treatment plan was performed with the both codes. The dose components to normal brain, tumor and planning target volume (PTV) were calculated and compared in case of one radiation field and combined two fields. The depth dose distributions and the maximum doses in regions of interest were compared. Calculations with the treatment planning systems for the thermal neutron induced (10B and nitrogen) dose components and photon dose were in good agreement. Higher discrepancy in the fast neutron dose calculations was found. In case of combined twofield treatment plan, overall discrepancy of the total maximum weighted dose was ~3% for normal brain and PTV and ~4% for tumor dose.

    AB - Three treatment planning systems developed for clinical BNCT use are SERA developed by INL/Montana State University, NCTPlan developed by the HarvardMIT and the CNEA group and JCDS developed by JAEA in Japan. Previously, performance of the SERA and NCTPlan has been compared in various studies. In this preliminary study, the dose calculations performed with SERA and JCDS systems were compared in single brain cancer patient case with the FiR 1 epithermal neutron beam. A twofield brain cancer treatment plan was performed with the both codes. The dose components to normal brain, tumor and planning target volume (PTV) were calculated and compared in case of one radiation field and combined two fields. The depth dose distributions and the maximum doses in regions of interest were compared. Calculations with the treatment planning systems for the thermal neutron induced (10B and nitrogen) dose components and photon dose were in good agreement. Higher discrepancy in the fast neutron dose calculations was found. In case of combined twofield treatment plan, overall discrepancy of the total maximum weighted dose was ~3% for normal brain and PTV and ~4% for tumor dose.

    KW - treatment planning

    KW - dose calculation

    KW - MCNP

    KW - SERA

    KW - JCDS

    M3 - Conference article in proceedings

    SN - 978-888-28616-7-4

    SP - 583

    EP - 586

    BT - Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer

    A2 - Zonta, A.

    PB - ENEA

    ER -

    Koivunoro H, Kumada H, Seppälä T, Kotiluoto P, Auterinen I, Kankaanranta L et al. Dose calculations with SERA and JCDS treatment planning systems. In Zonta A, editor, Proceedings of the 13th International Congress on Neutron Capture Therapy - BNCT: a new option against cancer. ENEA. 2008. p. 583-586