EEG reactivity in coma: Comparing stimuli

Antti Tolonen, B Young, M Särkelä

Research output: Contribution to journalOther journal contributionScientific


Background: EEG reactivity has prognostic utility in coma. However, the relative effectiveness of various stimuli has not been systematically explored. Methods: We chose 200 adult patients with in coma in ICU and excluded patients who were brain dead or on anesthetic doses of sedative medication. EEGs were recorded while applying stimuli randomly: vocal stimulus (vS): calling of the patient's first name; "noisy stimulus" (NS): tone of 120 dB into both ears; nasal stimulus (NaS): tissue paper inserted into the nares; nailbed stimulus (NBS): pressure on the nailbed of index finger. Results: The percentage in which reactivity to one stimulus was associated with reactivity to another stimulus is shown in Table: Conclusions: It is best to apply more than one stimulus modality when assessing EEG reactivity. With respect to associations, NS is the least effective stimulus
Original languageEnglish
Pages (from-to)S17
JournalCanadian Journal of Neurological Sciences
Issue number3 (Suppl. 1)
Publication statusPublished - 2014
MoE publication typeNot Eligible
Event49th Annual Congress of the Canadian Neurological Sciences Federation, Banff, Alberta, Canada, 3 - 6 June 2014 -
Duration: 1 Jan 2014 → …


  • EEG
  • coma
  • reactivity

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