TY - JOUR
T1 - Effect of deterpenated origanum majorana l. Essential oil on the physicochemical and biological properties of chitosan/β-chitin nanofibers nanocomposite films
AU - Fernández-Marín, Rut
AU - Mujtaba, Muhammad
AU - Cansaran-Duman, Demet
AU - Salha, Ghada Ben
AU - Sánchez, Ma Ángeles Andrés
AU - Labidi, Jalel
AU - Fernandes, Susana C.M.
N1 - Funding Information:
Acknowledgments: R.F.-M. would like to express her gratitude to the Department of Economic Development and Infrastructures of the Basque Government (scholarship of young researchers training and IT 1008-16) for supporting financially this research. The authors would like to give thanks for technical and human support provided by SGIker (UPV/EHU/ERDF, EU). S.C.M.F. is the recipient of an E2S UPPA Partnership Chair MANTA (Marine Materials) supported by the ‘Investissements d’Avenir’ French programme managed by the French National Research Agency (ANR-16-IDEX-0002), by the Region Nouvelle-Aquitaine and by the Communaute d’Agglomeration du Pays Basque, France.
Funding Information:
This research was funded by the Basque Country Government (IT 1008-16). R.F.-M. would like to express her gratitude to the Department of Economic Development and Infrastructures of the Basque Government (scholarship of young researchers training and IT 1008-16) for supporting financially this research. The authors would like to give thanks for technical and human support provided by SGIker (UPV/EHU/ERDF, EU). S.C.M.F. is the recipient of an E2S UPPA Partnership Chair MANTA (Marine Materials) supported by the ?Investissements d?Avenir? French programme managed by the French National Research Agency (ANR-16-IDEX-0002), by the Region Nouvelle-Aquitaine and by the Communaute d?Agglomeration du Pays Basque, France.
Funding Information:
Funding: This research was funded by the Basque Country Government (IT 1008-16).
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/5/7
Y1 - 2021/5/7
N2 - Herein, the effect of three deterpenated fractions from Origanum majorana L. essential oil on the physicochemical, mechanical and biological properties of chitosan/β-chitin nanofibers-based nanocomposite films were investigated. In general, the incorporation of Origanum majorana L. original essential oil or its deterpenated fractions increases the opacity of the nanocomposite films and gives them a yellowish color. The water solubility decreases from 58% for chitosan/β-chitin nanofibers nanocomposite film to around 32% for the nanocomposite films modified with original essential oil or its deterpenated fractions. Regarding the thermal stability, no major changes were observed, and the mechanical properties decreased. Interestingly, data show differences on the biological properties of the materials depending on the incorporated deterpenated fraction of Origanum majorana L. essential oil. The nanocomposite films prepared with the deterpenated fractions with a high concentration of oxygenated terpene derivatives show the best antifungal activity against Aspergillus niger, with fungal growth inhibition of around 85.90%. Nonetheless, the only nanocomposite film that does not present cytotoxicity on the viability of L929 fibroblast cells after 48 and 72 h is the one prepared with the fraction presenting the higher terpenic hydrocarbon content (87.92%). These results suggest that the composition of the deterpenated fraction plays an important role in determining the biological properties of the nanocomposite films.
AB - Herein, the effect of three deterpenated fractions from Origanum majorana L. essential oil on the physicochemical, mechanical and biological properties of chitosan/β-chitin nanofibers-based nanocomposite films were investigated. In general, the incorporation of Origanum majorana L. original essential oil or its deterpenated fractions increases the opacity of the nanocomposite films and gives them a yellowish color. The water solubility decreases from 58% for chitosan/β-chitin nanofibers nanocomposite film to around 32% for the nanocomposite films modified with original essential oil or its deterpenated fractions. Regarding the thermal stability, no major changes were observed, and the mechanical properties decreased. Interestingly, data show differences on the biological properties of the materials depending on the incorporated deterpenated fraction of Origanum majorana L. essential oil. The nanocomposite films prepared with the deterpenated fractions with a high concentration of oxygenated terpene derivatives show the best antifungal activity against Aspergillus niger, with fungal growth inhibition of around 85.90%. Nonetheless, the only nanocomposite film that does not present cytotoxicity on the viability of L929 fibroblast cells after 48 and 72 h is the one prepared with the fraction presenting the higher terpenic hydrocarbon content (87.92%). These results suggest that the composition of the deterpenated fraction plays an important role in determining the biological properties of the nanocomposite films.
KW - Beta-chitin nanofibers
KW - Biological properties
KW - Chitosan
KW - Deterpenated fractions
KW - Nanocomposite films
KW - Origanum majorana L. essential oil
UR - http://www.scopus.com/inward/record.url?scp=85106158299&partnerID=8YFLogxK
U2 - 10.3390/polym13091507
DO - 10.3390/polym13091507
M3 - Article
C2 - 34067109
AN - SCOPUS:85106158299
SN - 2073-4360
VL - 13
JO - Polymers
JF - Polymers
IS - 9
M1 - 1507
ER -