Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 817-825 |
| Number of pages | 9 |
| Journal | International Dairy Journal |
| Volume | 11 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2001 |
| MoE publication type | A1 Journal article-refereed |
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Effect of galacto-oligosaccharide supplementation on human faecal microflora and on survival and persistence of Bifidobacterium lactis Bb-12 in the gastrointestinal tract. / Alander, Minna; Mättö, Jaana; Kneifel, W.; Johansson, M.; Kögler, B.; Crittenden, Ross; Mattila-Sandholm, Tiina; Saarela, Maria (Corresponding Author).
In: International Dairy Journal, Vol. 11, No. 10, 2001, p. 817-825.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Effect of galacto-oligosaccharide supplementation on human faecal microflora and on survival and persistence of Bifidobacterium lactis Bb-12 in the gastrointestinal tract
AU - Alander, Minna
AU - Mättö, Jaana
AU - Kneifel, W.
AU - Johansson, M.
AU - Kögler, B.
AU - Crittenden, Ross
AU - Mattila-Sandholm, Tiina
AU - Saarela, Maria
PY - 2001
Y1 - 2001
N2 - Galacto-oligosaccharides (GOS) are considered to have bifidogenic properties in humans. To study the effect of GOS-containing syrup (60% GOS) alone or together with the probiotic strain Bifidobacterium lactis Bb-12 on selected components of the faecal flora, and the effect of GOS supplementation on colonisation of B. lactis Bb-12, a feeding trial on 30 healthy volunteers was performed. Mean numbers of bifidobacteria increased slightly in all study groups during the feeding period. Isolates having the identical RAPD genotype with B. lactis Bb-12 were detected in high numbers in the Bb-12 group and in the GOS-containing syrup+Bb-12 group indicating a good survival of B. lactis Bb-12 through the gastrointestinal tract. No differences in the prevalence or numbers of isolates with B. lactis Bb-12 genotype could be observed between groups suggesting that GOS-containing syrup did not enhance the survival or persistence of B. lactis Bb-12 in the gut.
AB - Galacto-oligosaccharides (GOS) are considered to have bifidogenic properties in humans. To study the effect of GOS-containing syrup (60% GOS) alone or together with the probiotic strain Bifidobacterium lactis Bb-12 on selected components of the faecal flora, and the effect of GOS supplementation on colonisation of B. lactis Bb-12, a feeding trial on 30 healthy volunteers was performed. Mean numbers of bifidobacteria increased slightly in all study groups during the feeding period. Isolates having the identical RAPD genotype with B. lactis Bb-12 were detected in high numbers in the Bb-12 group and in the GOS-containing syrup+Bb-12 group indicating a good survival of B. lactis Bb-12 through the gastrointestinal tract. No differences in the prevalence or numbers of isolates with B. lactis Bb-12 genotype could be observed between groups suggesting that GOS-containing syrup did not enhance the survival or persistence of B. lactis Bb-12 in the gut.
U2 - 10.1016/S0958-6946(01)00100-5
DO - 10.1016/S0958-6946(01)00100-5
M3 - Article
VL - 11
SP - 817
EP - 825
JO - International Dairy Journal
JF - International Dairy Journal
SN - 0958-6946
IS - 10
ER -