Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 941-949 |
| Number of pages | 8 |
| Journal | Clinical Nutrition |
| Volume | 32 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2013 |
| MoE publication type | A1 Journal article-refereed |
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Keywords
- cereal fibre
- clucose metabolism
- inflammatory markers
- insulin sensitivity
- metabolic syndrome
- wholegrain
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Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors : A randomised controlled two-centre. / Giacco, R. (Corresponding Author); Lappi, J.; Costabile, G.; Kolehmainen, M.; Schwab, U.; Landberg, R.; Uusitupa, M.; Poutanen, Kaisa; Pacini, G.; Rivellese, A.A.; Riccardi, G.; Mykkänen, H.
In: Clinical Nutrition, Vol. 32, No. 6, 2013, p. 941-949.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors
T2 - A randomised controlled two-centre
AU - Giacco, R.
AU - Lappi, J.
AU - Costabile, G.
AU - Kolehmainen, M.
AU - Schwab, U.
AU - Landberg, R.
AU - Uusitupa, M.
AU - Poutanen, Kaisa
AU - Pacini, G.
AU - Rivellese, A.A.
AU - Riccardi, G.
AU - Mykkänen, H.
PY - 2013
Y1 - 2013
N2 - BACKGROUND & AIMS: Intervention studies investigating the effects of wholegrain intake on glucose and insulin metabolism have provided conflicting results. Aim of this study was the evaluation of glucose and insulin metabolism in response to long-term consumption of rye and whole wheat compared with a diet containing the same amount of refined cereal foods, in individuals with metabolic syndrome from two European locations (Kuopio-Finland/Naples-Italy). METHODS: 146 individuals of both genders, age range 40-65 years with metabolic syndrome, were recruited to this study with parallel groups. After a 2-4 week run-in period, participants were assigned to a diet based on wholegrain (wholegrain group) or on refined cereal products (control group), each one for a duration of 12 weeks. Peripheral insulin sensitivity, assessed by FSIGT, lipids and inflammatory markers were measured before and at the end of intervention. RESULTS: 61 participants in the control group and 62 in the wholegrain group completed the dietary intervention. Compliance to the two diets was good. At the end of the intervention, insulin sensitivity indices and secretion (SI, QUICKI, DI, dAIRG) and lipids and inflammatory markers did not change significantly in the wholegrain and control groups as compared with baseline and no differences between the two groups were observed. CONCLUSIONS: Wholegrain cereal foods consumption compared with refined cereals for 12 weeks did not affect peripheral insulin sensitivity.
AB - BACKGROUND & AIMS: Intervention studies investigating the effects of wholegrain intake on glucose and insulin metabolism have provided conflicting results. Aim of this study was the evaluation of glucose and insulin metabolism in response to long-term consumption of rye and whole wheat compared with a diet containing the same amount of refined cereal foods, in individuals with metabolic syndrome from two European locations (Kuopio-Finland/Naples-Italy). METHODS: 146 individuals of both genders, age range 40-65 years with metabolic syndrome, were recruited to this study with parallel groups. After a 2-4 week run-in period, participants were assigned to a diet based on wholegrain (wholegrain group) or on refined cereal products (control group), each one for a duration of 12 weeks. Peripheral insulin sensitivity, assessed by FSIGT, lipids and inflammatory markers were measured before and at the end of intervention. RESULTS: 61 participants in the control group and 62 in the wholegrain group completed the dietary intervention. Compliance to the two diets was good. At the end of the intervention, insulin sensitivity indices and secretion (SI, QUICKI, DI, dAIRG) and lipids and inflammatory markers did not change significantly in the wholegrain and control groups as compared with baseline and no differences between the two groups were observed. CONCLUSIONS: Wholegrain cereal foods consumption compared with refined cereals for 12 weeks did not affect peripheral insulin sensitivity.
KW - cereal fibre
KW - clucose metabolism
KW - inflammatory markers
KW - insulin sensitivity
KW - metabolic syndrome
KW - wholegrain
U2 - 10.1016/j.clnu.2013.01.016
DO - 10.1016/j.clnu.2013.01.016
M3 - Article
VL - 32
SP - 941
EP - 949
JO - Clinical Nutrition
JF - Clinical Nutrition
SN - 0261-5614
IS - 6
ER -