Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans

Soile Gråsten, Kirsi-Helena Liukkonen, Angeliki Chrevatidis, Hani El-Nezami, Kaisa Poutanen, Hannu Mykkänen (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

62 Citations (Scopus)

Abstract

The effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function were compared in healthy humans. In a parallel study 14 subjects consumed daily for three weeks 13 g of wheat pentosan or inulin baked in wheat bread. Activities of bacterial enzymes (β-glucuronidase, β-glucosidase, urease) and concentrations of bacterial metabolites (short chain fatty acids, phenol, p-cresol) in feces, bowel function and intestinal symptoms were measured at the beginning and end of the intervention period. Changes in most parameters studied were similar in subjects receiving pentosan or inulin bread, but pentosan increased total SCFA (P = 0.048) and butyrate (P = 0.009) concentrations in feces more than inulin. Pentosan also increased the occurrence of flatulence (P < 0.05). Pentosan appears to be more easily fermented than inulin, and due to the increase in the fecal butyrate concentration may have favourable effects on colonic health.
Original languageEnglish
Pages (from-to)1503-1514
Number of pages12
JournalNutrition Research
Volume23
Issue number11
DOIs
Publication statusPublished - 2003
MoE publication typeA1 Journal article-refereed

Fingerprint

Inulin
Microbiota
Triticum
Butyrates
Bread
Feces
Glucosidases
Flatulence
Urease
Volatile Fatty Acids
Glucuronidase
Phenol
Health
Enzymes

Keywords

  • inulin
  • pentosan
  • microbiota
  • intestinal metabolism
  • bowel function
  • human
  • health
  • health-effects
  • human health
  • wheat

Cite this

Gråsten, Soile ; Liukkonen, Kirsi-Helena ; Chrevatidis, Angeliki ; El-Nezami, Hani ; Poutanen, Kaisa ; Mykkänen, Hannu. / Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. In: Nutrition Research. 2003 ; Vol. 23, No. 11. pp. 1503-1514.
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Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. / Gråsten, Soile; Liukkonen, Kirsi-Helena; Chrevatidis, Angeliki; El-Nezami, Hani; Poutanen, Kaisa; Mykkänen, Hannu (Corresponding Author).

In: Nutrition Research, Vol. 23, No. 11, 2003, p. 1503-1514.

Research output: Contribution to journalArticleScientificpeer-review

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AU - Gråsten, Soile

AU - Liukkonen, Kirsi-Helena

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AU - Poutanen, Kaisa

AU - Mykkänen, Hannu

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