Efficiency of TiO2 nanoparticles of different sizes as UV-B light skin-protective fraction in sunscreens

Alexey P. Popov, Alexander V. Priezzhev, Jürgen Lademann, Risto Myllylä

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

1 Citation (Scopus)


One of the acute problems of raising the life standard of people nowadays is to protect human skin against harmful UV solar radiation. The aim of this paper is to evaluate the most appropriate size of titanium dioxide (TiO2) fine particles that can be imbedded into the skin in order to achieve the maximal attenuation of the UV-B light. The in-depth distribution in the skin of TiO2 particles achieved with the topically applied sunscreens is determined experimentally by the tape-stripping technique. Computer code implementing the Monte Carlo method is used to simulate photon migration through a 20-μm thick horny layer matrix partially filled with nano-sized TiO2 spheres. Dependencies of the portions of the most harmful UV radiation with the wavelength of 290.5 nm absorbed by and reflected from, as well as transmitted through the horny layer on the concentration of TiO2 particles are obtained and analyzed.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2004
Subtitle of host publicationOptical Technologies in Biophysics and Medicine VI
EditorsValery V. Tuchin
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Print)978-0-8194-5752-3
Publication statusPublished - 7 Oct 2005
MoE publication typeA4 Article in a conference publication
EventSaratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI - Saratov, Russian Federation
Duration: 21 Sept 200424 Sept 2004

Publication series

SeriesProceedings of SPIE


ConferenceSaratov Fall Meeting 2004
Country/TerritoryRussian Federation


  • Horny layer
  • Human skin
  • Monte Carlo simulation
  • Photon migration
  • Titanium dioxide particles
  • UV radiation


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