Abstract
Pharmaceutical biotechnology is big business; it currently consists of 1/6 of the total volume of the pharmaceutical market and continues to grow steadily. Expression of therapeutic proteins is mainly done in living cells, although ‘cell free protein synthesis’ (CFPS) or ‘in-vitro transcription translation’ (IVTT) is beginning to emerge as an alternative for commercial production. In this article we will highlight some of the more recent advances in protein expression systems for the production of pharmaceutical proteins. We will also discuss current trends in the engineering of pharmaceutical proteins with improved properties.
| Original language | English |
|---|---|
| Journal | European Pharmaceutical Review |
| Volume | 2014 |
| Issue number | 4 |
| Publication status | Published - 5 Sept 2014 |
| MoE publication type | B1 Article in a scientific magazine |